Publications

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Publications

Representative publications (396 publication in total)
1. Molecular nanocarbon chemistry
(A28) “Methylene-bridged [6]-, [8]-, and [10]cycloparaphenylenes: Size-dependent properties and paratropic belt currents” H. Kono et al., J. Am. Chem. Soc. 2023, 145, ASAP.
(A27) “Synthesis, properties, and material hybridization of bare aromatic polymers enabled by dendrimer support” S. Fujiki et al., Nature Commun. 2022, 13, 5358.
(A26) “Perfluorocycloparaphenylenes” H. Shudo et al., Nature Commun. 2022, 13, 3713.
(A25) “Synthesis of a Möbius carbon nanobelt” Y. Segawa et al., Nature Synth. 2022,1, 535-541.
(A24) “Infinitene: A helically twisted figure-eight [12]circulene topoisomer” M. Krzeszewski et al., J. Am. Chem. Soc. 2022, 144, 862-871.
(A23) “Diversity-oriented synthesis of nanographenes enabled by dearomative annulative π-extension” W. Matsuoka et al., Nature Commun. 2021, 12, 3940.
(A22) “Double-helix supramolecular nanofibers assembled from negatively curved nanographenes” K. Kato et al., J. Am. Chem. Soc. 2021, 143, 5465-5469.
(A21) “Synthesis of a zigzag carbon nanobelt” K. Y. Cheung et al., Nature Chem. 2021, 13, 255-259.
(A20) “Chemical synthesis of carbon nanorings and nanobelts” Y. Li et al., Acc. Mater. Res. 2021, 2, 681-691.
(A19) “Creation of negatively curved polyaromatics enabled by annulative coupling that forms an eight-membered ring” S. Matsubara et al., Nature Catal. 2020, 3, 710-718.
(A18) “A nonalternant aromatic belt: Methylene-bridged [6]cycloparaphenylene synthesized from pillar[6]arene” Y. Li et al., J. Am. Chem. Soc. 2020, 142, 12850-12856.
(A17) “Topologically unique molecular nanocarbons” Y. Segawa et al., Acc. Chem. Res. 2019, 52, 2760-2767.
(A16) “Topological molecular nanocarbons: all-benzene catenane and trefoil knot” Y. Segawa et al., Science 2019, 365, 272-276.
(A15) “Strength of carbon nanotubes depends on their chemical structures” A. Takakura et al., Nature Commun. 2019, 10, 3040.
(A14) “Polycyclic arene synthesis by annulative π-extension” H. Ito et al., J. Am. Chem. Soc. 2019, 141, 3-10.
(A13) “Ultra-narrow-band thermal exciton radiation in intrinsic one-dimensional semiconductors” T. Nishihara et al., Nature Commun. 2018, 9, 3144. 05598-3
(A12) “A water-soluble warped nanographene: Synthesis and applications for photo-induced cell death” H.-A. Lin et al., Angew. Chem. Int. Ed. 2018, 57, 2874-2878.
(A11) “Synthesis of partially and fully fused polyaromatics by annulative chlorophenylene dimerization” Y. Koga et al., Science 2018, 359, 435-439.
(A10) “Electrically activated conductivity and white light emission of a hydrocarbon nanoring-iodine assembly” N. Ozaki et al., Angew. Chem. Int. Ed. 2017, 56, 11196-11202.
(A9)    “Synthesis of a carbon nanobelt” G. Povie et al., Science 2017, 356, 172-175.
(A8)    “Synthesis and structural features of quadruple helicenes: Highly distorted π systems enabled by accumulation of helical repulsions” T. Fujikawa et al., J. Am. Chem. Soc. 2016, 138, 3587-3595.
(A7)    “Structurally uniform and atomically precise carbon nanostructures” Y. Segawa et al., Nature Rev. Mat. 2016, 1, 15002.
(A6)    “One-shot K-region-selective annulative π-extension for nanographene synthesis and functionalization” K. Ozaki et al., Nature Commun. 2015, 6, 6251.
(A5)    “All-benzene carbon nanocages: Size-selective synthesis, photophysical properties, and crystal structure” K. Matsui et al., J. Am. Chem. Soc. 2014, 136, 16452-16458.
(A4)    “A grossly warped nanographene and the consequences of multiple odd-membered-ring defects” K. Kawasumi et al., Nature Chem. 2013, 5, 739-744.
(A3)    “Initiation of carbon nanotube growth by well-defined carbon nanorings” H. Omachi et al., Nature Chem. 2013, 5, 572-576.
(A2)    “Synthesis of cycloparaphenylenes and related carbon nanorings: A step toward the controlled synthesis of carbon nanotubes” H. Omachi et al., Acc. Chem. Res. 2012, 45, 1378-1389.
(A1)    “Selective synthesis of [12]cycloparaphenylene” H. Takaba et al., Angew. Chem. Int. Ed. 2009, 48, 6112-6116.

2. Synthetic methodology
(B23) “Lithium-mediated mechanochemical cyclodehydrogenation” K. Fujishiro et al., J. Am. Chem. Soc. 2023, 145, 8163-8175.
(B22) “π-Extended rubrenes via dearomative annulative π-extension reaction” W. Matsuoka et al., J. Am. Chem. Soc. 2023, 145, 658-666.
(B21) “Selective transformation of strychnine and 1,2-disubstituted benzenes by C-H borylation” Y. Saito et al., Chem 2020, 6, 985-993.
(B20) “Rapid access to nanographenes and fused heteroaromatics by palladium-catalyzed annulative π-extension reaction of unfunctionalized aromatics with diiodobiaryls” W. Matsuoka et al., Angew. Chem. Int. Ed. 2017, 56, 12224-12228.
(B19) “Annulative π-extension (APEX): An enabling reaction for rapid access to fused aromatics, heteroaromatics, and nanographenes” H. Ito et al., Angew. Chem. Int. Ed. 2017, 56, 11144-11164.
(B18) “Catalytic dehydrogenative C-H imidation of arenes enabled by photo-generated hole donation to sulfonimide” E. Ito et al., Chem 2017, 2, 383-392.
(B17) “Decarbonylative organoboron cross-coupling of esters by nickel catalysis” K. Muto et al., Nature Commun. 2015, 6, 7508.
(B16) “para-C-H borylation of benzene derivatives by a bulky iridium catalyst” Y. Saito et al., J. Am. Chem. Soc. 2015, 137, 5193-5198.
(B15) “Catalytic C-H imidation of aromatic cores of functional molecules: Ligand-accelerated Cu catalysis and application to materials- and biology-oriented aromatics” T. Kawakami et al., J. Am. Chem. Soc. 2015, 137, 2460-2463.
(B14) “Synthesis and characterization of hexaarylbenzenes with five or six different substituents enabled by programmed synthesis” S. Suzuki et al., Nature Chem. 2015, 7, 227-233.
(B13) “Concise syntheses of dictyodendrins A and F by a sequential C-H functionalization strategy” A. D. Yamaguchi et al., J. Am. Chem. Soc. 2015, 137, 644-647.
(B12) “C-H bond functionalization: Emerging synthetic tools for natural products and pharmaceuticals” J. Yamaguchi et al., Angew. Chem. Int. Ed. 2012, 51, 8960-9009.
(B11) “Decarbonylative C-H coupling of azoles and aryl esters: Unprecedented nickel catalysis and application to the synthesis of muscoride A” K. Amaike et al., J. Am. Chem. Soc. 2012, 134, 13573-13576.
(B10) “Nickel-catalyzed C-H/C-O coupling of azoles with phenol derivatives” K. Muto et al., J. Am. Chem. Soc. 2012, 134, 169-172.
(B9)    “Direct aylation of polycyclic aromatic hydrocarbons through palladium catalysis” K. Mochida et al., J. Am. Chem. Soc. 2011, 133, 10716-10719.
(B8) “A general catalyst for the beta-selective C-H bond arylation of thiophenes with iodoarenes” K. Ueda et al., Angew. Chem. Int. Ed. 2010, 49, 8946-8949.
(B7) “Programmed synthesis of tetraarylthiophenes through sequential C-H arylation” S. Yanagisawa et al., J. Am. Chem. Soc. 2009, 131, 14622-14623.
(B6) “Potassium t-butoxide alone can promote the biaryl coupling of electron-deficient nitrogen heterocycles and haloarenes” S. Yanagisawa et al., Org. Lett. 2008, 10, 4673-4676.
(B5) “Rh-catalyzed arylation and alkenylation of C₆₀ using organoboron compounds” M. Nambo et al., J. Am. Chem. Soc. 2007, 129, 8080-8081.
(B4) “Direct C-H arylation of (hetero)arenes with aryl iodides via rhodium catalysis” S. Yanagisawa et al., J. Am. Chem. Soc. 2006, 128, 11748-11749.
(B3) “Triarylethene-based extended π-systems: Programmable synthesis and photophysical properties” K. Itami et al., J. Org. Chem. 2005, 70, 2778-2792.
(B2) “Sequential assembly strategy for tetrasubstituted olefin synthesis using vinyl 2-pyrimidyl sulfide as a platform” K. Itami et al., J. Am. Chem. Soc. 2004, 126, 11778-11779.
(B1) “Diversity-oriented synthesis of multisubstituted olefins through the sequential integration of palladium-catalyzed cross-coupling reactions. 2-Pyridyldimethyl(vinyl)silane as a versatile platform for olefin synthesis” K. Itami et al., J. Am. Chem. Soc. 2001, 123, 11577-11585.

3. Chemical chronobiology
(C7)    “Reversible modulation of circadian time with chronophotopharmacology” D. Kolarski et al., Nature Commun. 2021, 12, 3164.
(C6)    “Photopharmacological manipulation of mammalian CRY1 for regulation of the circadian clock” D. Kolarski et al., J. Am. Chem. Soc. 2021, 143, 2078-2087.
(C5)    “Small molecules modulating mammalian biological clocks: Exciting new opportunities for synthetic chemistry” K. Amaike et al., Chem 2020, 6, 2186-2198.
(C4)    “Isoform-selective regulation of mammalian cryptochromes” S. Miller et al., Nature Chem. Biol. 2020, 16, 676-685.
(C3)    “Controlling the circadian clock with high temporal resolution through photodosing” J. Am. Chem. Soc. 2019, 141, 15784-15791.
(C2)    “Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth” T. Oshima et al., Science Adv. 2019, 5, eau9060.
(C1)    “C-H activation generates period-shortening molecules that target Cryptochrome in the mammalian circadian clock” T. Oshima et al., Angew. Chem. Int. Ed. 2015, 54, 7193-7197.

4. Plant chemical biology
(D9)    “Discovery of 2,6-dihalopurines as stomata opening inhibitors: Implication of an LRX-mediated H⁺-ATPase phosphorylation pathway” A. Ueda et al., ACS Chem. Biol. 2023, 18, 347-355.
(D8)    “Identification of stomatal-regulating molecules from de novo arylamine collection through aromatic C-H amination” Y. Toda et al., Sci. Rep. 2022, 12, 949.
(D7)    “Casein kinese 1 family regulates PRR5 and TOC1 in the Arabidopsis circadian clock” T. N Uehara et al., Proc. Nat. Acad. Sci. 2019, 116, 11528-11536.
(D6)    “Discovery of plant growth stimulants by C-H arylation of 2-azahypoxanthine” H. Kitano et al., Org. Lett. 2018, 20, 5684-5687.
(D5)    “Discovery of shoot branching regulator targeting strigolactone receptor DWARF14” M. Yoshimura et al., ACS Cent. Sci. 2018, 4, 230-234.
(D4)    “Chemical hijacking of auxin signaling with an engineered auxin-TIR1 pair” N. Uchida et al., Nature Chem. Biol. 2018, 14, 299-305.
(D3)    “Discovery of synthetic small molecules that enhance the number of stomata: C-H functionalization chemistry for plant biology” A. Ziadi et al., Chem. Commun. 2017, 53, 9632-9635.
(D2)    “The AMOR arabinogalactan sugar chain induces pollen-tube competency to respond to ovular guidance” A. G. Mizukami et al., Curr. Biol. 2016, 26, 1091-1097.
(D1)    “Probing strigolactone receptors in Striga hermonthica with fluorescence” Y. Tsuchiya et al., Science 2015, 349, 864-868.

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Publications (all list)

[Preprints or submitted]
(P9) The first synthesis of carbon nanobelts: The ‘belt’ festival and the drama behind
Kenichiro Itami
Moving Moments of Scientists, Kagaku Dojin, 2023, submitted.

(P8) Photoredox-catalyzed decarboxylative coupling of aryl bromides with N-protected glycine as aminomethyl source
Jaehyun Jung, Takumi Kinoshita, Yuta Makihara, Yota Sakakibara, Kazuma Amaike, Kei Murakami, Kenichiro Itami
Submitted

(P7) Development of a novel PET ligand, [¹¹C]GO289 targeting casein kinase 2 expressed in the brain
Aya Ogata, Takashi Yamada, Saori Hattori, Hiroshi Ikenuma, Junichiro Abe, Masanori Ichise, Masaaki Suzuki, Kengo Ito, Takashi Kato, Kazuma Amaike, Tsuyoshi Hirota, Kenichiro Itami, Yasuyuki Kimura
Submitted.

(P6) Half-substituted fluorocycloparaphenylenes with high symmetry: Synthesis, properties and derivatization to densely substituted carbon nanorings
Hiroki Shudo, Motonobu Kuwayama, Yasutomo Segawa, Akiko Yagi, Kenichiro Itami^[ChemRxiv, DOI: 10.26434/chemrxiv-2023-zsvnt

(P5) Adamantane-annulation to arenes: A simple strategy for property modulation of aromatic π-systems
Takaku Yoshihara, Hiroki Shudo, Akiko Yagi, Kenichiro Itami
ChemRxiv, DOI: 10.26434/chemrxiv-2023-1jsp4

(P4) Expanded [2,1][n]carbohelicenes with 15- and 17-benzene rings
Michihisa Toya, Takuya Omine, Fumitaka Ishiwari, Akinori Saeki, Hideto Ito, Kenichiro Itami
ChemRxiv, DOI: 10.26434/chemrxiv-2023-k9pzj

(P3) Switchable decarboxylation by energy- or electron-transfer photocatalysis
Yota Sakakibara, Kenichiro Itami, Kei Murakami
ChemRxiv, DOI: 10.26434/chemrxiv-2022-drf9p

(P2) A unique small molecule pair controls the plant circadian clock
Takahiro N. Uehara, Saori Takao, Hiromi Matsuo, Ami N. Saito, Eisuke Ota, Azusa Ono, Kenichiro Itami, Toshinori Kinoshita, Junichiro Yamaguchi, Norihito Nakamichi
bioRxiv, DOI: 10.1101/2020.05.25.113746

(P1) Effect of nanocarbon molecules on the Arabidopsis thaliana transcriptome
Norihito Nakamichi, Ayato Sato, Yusuke Aihara, Toshinori Kinoshita, Yasutomo Segawa, Kazuma Amaike, Kenichiro Itami
bioRxiv, DOI: 10.1101/2020.05.22.110171v1

[Papers]

(396) Noncovalent modification of cycloparaphenylene by catenane formation using an active metal template strategy
Hisayasu Ishibashi, Manuel Rondelli, Hiroki Shudo, Takehisa Maekawa, Hideto Ito, Kiichi Mizukami, Nobuo Kimizuka, Akiko Yagi, Kenichiro Itami
Angew. Chem. Int. Ed. 2023, 62, Accepted Article. DOI: 10.1002/anie.202310613 Selected as Hot Paper.
ChemRxiv, DOI: 10.26434/chemrxiv-2023-3rq4x

(395) Divergent transformation of carboxylic acids through photocatalytic decarboxylation with hypervalent iodine reagents
Yota Sakakibara, Kenichiro Itami, Kei Murakami
Synth. Org. Chem. Jpn., in press.

(394) A small compound, HYGIC, promotes hypocotyl growth through ectopic ethylene response
Mizuki Murao, Rika Kato, Rina Hisamatsu, Hitoshi Endo, Yasuki Kawabata, Seisuke Kimura, Ayato Sato, Kenichiro Itami, Keiko U. Torii, Shinya Hagihara, Naoyuki Uchida
Plant Cell Physiol., Accepted Article.
DOI: 10.1093/pcp/pcad083

(393) Nickel/photoredox-catalyzed decarboxylative coupling of aryl bromides with N-protected glycine as an aminomethyl source
Jaehyun Jung, Takumi Kinoshita, Yuta Makihara, Yota Sakakibara, Kazuma Amaike, Kei Murakami, Kenichiro Itami
Synlett 2023, 34, Accepted Article. DOI: 10.1055/s-0041-1738444

(392) The first synthesis of carbon nanobelts: The ‘belt’ festival and the drama behind (account in Japanese)
Kenichiro Itami
Dramatic Synthetic Organic Chemistry, Kagaku Dojin, 2023, 74-75. https://www.ssocj.jp/symposium/80th/80th_book.pdf

(391) Adamantane annulation to arenes: A strategy for property modulation of aromatic π-systems
Takaku Yoshihara, Hiroki Shudo, Akiko Yagi, Kenichiro Itami
J. Am. Chem. Soc. 2023, 145, 11754-11763. DOI: 10.1021/jacs.3c02788
Featured in Chem-Station.
Highlighted in EE Times Japan, ITmedia, Yahoo! Japan, Synfacts.
ChemRxiv, DOI: 10.26434/chemrxiv-2023-1jsp4

(390) Expanded [2,1][n]carbohelicenes with 15- and 17-benzene rings
Michihisa Toya, Takuya Omine, Fumitaka Ishiwari, Akinori Saeki, Hideto Ito, Kenichiro Itami
J. Am. Chem. Soc. 2023, 145, 11553-11565. DOI: 10.1021/jacs.3c00109
ChemRxiv, DOI: 10.26434/chemrxiv-2023-k9pzj

(389) Identification and improvement of isothiocyanate-based inhibitors on stomatal opening to act as drought tolerance-conferring agrochemicals
Yusuke Aihara, Bumpei Maeda, Kanna Goto, Koji Takahashi, Mika Nomoto, Shigeo Toh, Wenxiu Ye, Yosuke Toda, Mami Uchida_,Eri Asai_, Yasuomi Tada, Kenichiro Itami_,Ayato Sato_, Kei Murakami, Toshinori Kinoshita
Nature Commun. 2023, 14, 2665. DOI: 10.1038/s41467-023-38102-7
Highlighted in Chunichi Shimbun, Asahi Shimbun, Kyodo Tsushin, Kagaku Shimbun.

(388) Development of a novel PET ligand, [¹¹C]GO289 targeting CK2 expressed in the brain
Aya Ogata, Takashi Yamada, Saori Hattori, Hiroshi Ikenuma, Junichiro Abe, Mari Tada, Masanori Ichise, Masaaki Suzuki, Kengo Ito, Takashi Kato, Kazuma Amaike, Tsuyoshi Hirota, Akiyoshi Kakita, Kenichiro Itami, Yasuyuki Kimura
Bioorg. Med. Chem. Lett. 2023, 90, 129327.DOI: 10.1016/j.bmcl.2023.129327

(387) Methylene-bridged [6]-, [8]-, and [10]cycloparaphenylenes: Size-dependent properties and paratropic belt currents
Hideya Kono, Yuanming Li, Riccardo Zanasi, Guglielmo Monaco, Francesco F. Summa, Lawrence T. Scott, Akiko Yagi, Kenichiro Itami
J. Am. Chem. Soc. 2023, 145, ASAP. DOI: 10.1021/jacs.2c13208

(386) Lithium-mediated mechanochemical cyclodehydrogenation
Kanna Fujishiro, Yuta Morinaka, Yohei Ono, Tsuyoshi Tanaka, Lawrence T. Scott, Hideto Ito, Kenichiro Itami
J. Am. Chem. Soc. 2023, 145, 8163-8175. DOI: 10.1021/jacs.3c01185
ChemRxiv, DOI: 10.26434/chemrxiv-2023-k4z34

(385) Identification of a pluripotency-inducing small compound, PLU, that induces callus formation via Heat Shock Protein 90-mediated activation of auxin signaling
Yuki Nakashima, Yuka Kobayashi, Mizuki Murao, Rika Kato, Hitoshi Endo, Asuka Higo, Rie Iwasaki, Mikiko Kojima, Yumiko Takebayashi, Ayato Sato, Mika Nomoto, Hitoshi Sakakibara, Yasuomi Tada, Kenichiro Itami, Seisuke Kimura, Shinya Hagihara, Keiko U. Torii, Naoyuki Uchida
Front. Plant Sci. 2023, 14, 1099587. DOI: 10.3389/fpls.2023.1099587

(384) One-step synthesis of polycyclic thianthrenes from unfunctionalized aromatics by thia-APEX reaction
Kou P. Kawahara, Hideto Ito, Kenichiro Itami
Org. Chem. Front. 2023, 10, 1880-1889. DOI: 10.1039/D2QO02058K
Selected as a cover of the journal.

(383) Synthesis and properties of methylene-bridged [6]cyclo-2,6-naphthylene
Nobushige Kai, Hideya Kono, Akiko Yagi, Kenichiro Itami
Synlett 2023, 18, online. DOI: 10.1055/a-2009-8219
Special issue honoring Masahiro Murakami’s contributions to science

(382) Discovery of 2,6-dihalopurines as stomata opening inhibitors: Implication of an LRX-mediated H⁺-ATPase phosphorylation pathway
Ayaka Ueda, Yusuke Aihara, Shinya Sato, Keiko Kano, Emi Mishiro-Sato, Hiroyuki Kitano, Ayato Sato, Kazuhiro J. Fujimoto, Takeshi Yanai, Kazuma Amaike, Toshinori Kinoshita, Kenichiro Itami
ACS Chem. Biol. 2023, 18, 347-355. DOI: 10.1021/acschembio.2c00771
Selected as a cover of the journal.
Highlighted in PhysOrg, EurekAlert!
ChemRxiv, DOI: 10.26434/chemrxiv-2022-6s89g

(381) Rapid access to polycyclic thiopyrylium compounds from unfunctionalized aromatics by thia-APEX reaction
Kou P. Kawahara, Hideto Ito, Kenichiro Itami
Chem. Commun. 2023, 59, 1157-1160. DOI: 10.1039/D2CC06706D

(380) π-Extended rubrenes via dearomative annulative π-extension reaction
Wataru Matsuoka, Kou P. Kawahara, Hideto Ito, David Sarlah, Kenichiro Itami
J. Am. Chem. Soc. 2023, 145, 658-666. DOI: 10.1021/jacs.2c11338 [detail]

(379) Making new forms of molecular nanocarbons
Kenichiro Itami
Toward Innovation in Organic Chemistry, Tokyo Kagaku Dojin, 2023, 171-182.

(378) C-H arylation enables synthesis of imidazole-4-carboxamide (ICA) based fairy chemicals with plant growth promoting activity
Ayaka Ueda, Kazuma Amaike, Yoko Shirotani, Robin Warstat, Hideto Ito, Jae-Hoon Choi, Hirokazu Kawagishi, Kenichiro Itami
Can. J. Chem. 2022, 100, Just-In article. DOI:10.1139/cjc-2022-0256
Special issue for Prof. Cathleen M. Crudden.

(377) Synthesis of Möbius carbon nanobelt: Construction of topological molecular nanocarbons
Yasutomo Segawa, Kenichiro Itami
Journal of Society of Automotive Engineers of Japan 2022, 77, 110-111.

(376) Synthesis, properties, and material hybridization of bare aromatic polymers enabled by dendrimer support
Shusei Fujiki, Kazuma Amaike, Akiko Yagi, Kenichiro Itami
Nature Commun. 2022, 13, 5358. DOI: 10.1038/s41467-022-33100-7
Featured in ChemStation.
Highlighted in ScienMag, EurekAlert!, Phys.org, True Viral News, Mirage News, Bioengineer.org, Swift Telecast.

(375) C-H borylation of arenes: Steric-controlled para-selectivity and application to molecular nanocarbons
Yasutomo Segawa, Mai nagase, Yutaro saito, Kenta Kato, Kenichiro Itami
J. Synth. Org. Chem. Jpn. 2022, 80, 994-999. DOI: 10.5059/yukigoseikyokaishi.80.994

(374) N-doped nonalternant aromatic belt via a six-fold annulative double N-arylation
Hiroki Sato, Rie Suizu, Tomoki Kato, Akiko Yagi, Yasutomo Segawa, Kunio Awaga, Kenichiro Itami
Chem. Sci. 2022,13, 9947-9951. DOI: 10.1039/D2SC02647C
ChemRxiv, DOI 10.26434/chemrxiv-2022-jqvv2

(373) New paradigms in molecular nanocarbon science
Iain A. Stepek, Mai Nagase, Akiko Yagi, Kenichiro Itami
Tetrahedron 2022, 123, 132907. DOI: 10.1016/j.tet.2022.132907
Special issue for the 65^th anniversary of Tetrahedron.

(372) Statistical verification of anomaly in chiral angle distribution of air-suspended carbon nanotubes
Taishi Nishihara, Akira Takakura, Keisuke Matsui, Kenichiro Itami, Yuhei Miyauchi
Nano Lett. 2022, 22, 5818-5824. DOI: 10.1021/acs.nanolett.2c01473

(371) Perfluorocycloparaphenylenes
Hiroki Shudo, Motonobu Kuwayama, Masafumi Shimasaki, Taishi Nishihara, Youhei Takeda, Takuya Kuwabara, Akiko Yagi, Yasutomo Segawa, Kenichiro Itami
Nature Commun. 2022, 13, 3713. DOI: 10.1038/s41467-022-31530-x
Highlighted in Chemical & Engineering News (ACS) and Chemistry Today.
Featured as Editors’ Highlights in Nature Commun.
ChemRxiv, DOI 10.33774/chemrxiv-2021-7kd63

(370) Synthesis of a Möbius carbon nanobelt
Yasutomo Segawa, Tsugunori Watanabe, Kotono Yamanoue, Motonobu Kuwayama, Kosuke Watanabe, Jenny Pirillo, Yuh Hijikata, Kenichiro Itami
Nature Synth. 2022, 1, 535-541. DOI: 10.1038/s44160-022-00075-8 [detail]
Selected as a Cover.
Highlighted in Nature, Nature Synth., and Chem (Cell Press).
Highlighted in Kyodo Tsushin and many other newspapers, Yahoo! News, Phys.org., EurekAlert!, Cosmos magazine, ScienMag, New Scientist, Bioengineer.org, Science Daily, Today UK News, Mirage News, Nanowerk, Azonano, Alert Breaking News, Tek Deeps, Scientific Russia, PhysicsWorld, Science and Life Russia, Mycom.
ChemRxiv, DOI 10.26434/chemrxiv-2021-w09lc

(369) Identification of stomatal-regulating molecules from de novo arylamine collection through aromatic C-H amination
Yosuke Toda, Gregory J. P. Perry, Shimpei Inoue, Eri Ito, Takahiro Kawakami, Mina R. Narouz, Koji Takahashi, Yusuke Aihara, Bumpei Maeda, Toshinori Kinoshita, Kenichiro Itami, Kei Murakami
Sci. Rep. 2022, 12, 949. DOI: 10.1038/s41598-022-04947-z

(368) C-H acyloxylation of polycyclic aromatic hydrocarbons
Yota Sakakibara, Kei Murakami, Kenichiro Itami
Org. Lett. 2022, 24, 602-607. DOI: 10.1021/acs.orglett.1c04030

(367) Phosphorylation of RNA polymerase II by CDKC;2 maintains the Arabidopsis circadian clock period
Takahiro N. Uehara, Takashi Nonoyama, Kyomi Taki, Keiko Kuwata, Ayato Sato, Kazuhiro J Fujimoto, Tsuyoshi Hirota, Hiromi Matsuo, Akari E Maeda, Azusa Ono, Tomoaki T Takahara, Hiroki Tsutsui, Takamasa Suzuki, Takeshi Yanai, Steve A Kay, Kenichiro Itami, Toshinori Kinoshita, Junichiro Yamaguchi, Norihito Nakamichi
Plant Cell Physiol. 2022, 63, 450-462. https://doi.org/10.1093/pcp/pcac011

(366) Synthesis of octagon-containing molecular nanocarbons
Greco González Miera, Satoshi Matsubara, Hideya Kono, Kei Murakami, Kenichiro Itami
Chem. Sci. 2022, 12, 1848-1868. DOI: 10.1039/D1SC05586K

(365) Infinitene: A helically twisted figure-eight [12]circulene topoisomer
Maciej Krzeszewski, Hideto Ito, Kenichiro Itami
J. Am. Chem. Soc. 2022, 144, 862-871. DOI: 10.1021/jacs.1c10807
Selected as “The Molecules of The Year 2021” by C&En News, ACS [link] [detail]
Highlighted in Chemistry Views [link], C&En News [link]
Selected as a Supplementary Cover Picture.
ChemRxiv DOI: 10.33774/chemrxiv-2021-pcwcc [link]

(364) Molecular nanocarbons add new dimensions to organic chemistry
Kenichiro Itami, Takehisa Maekawa
J. Org. Chem. 2021, 86, 14239-14241. DOI: 10.1021/acs.joc.1c02389
Org. Lett. 2021, 23, 8119-8121. DOI: 10.1021/acs.orglett.1c03331
Editorial for Virtual Issue “Molecular Nanocarbons: Organic Chemistry with Atomic Precision”.

(363) Stepwise generation of mono-, di-, and triply-reduced warped nanographenes: Charge-dependent aromaticity, surface nonequivalence, swing distortion and metal binding sites
Sarah N. Spisak, Zheng Zhou, Shuyang Liu, Qi Xu, Zheng Wei, Kenta Kato, Yasutomo Segawa, Kenichiro Itami, Andrey Yu. Rogachev, Marina A. Petrukhina
Angew. Chem. Int. Ed. 2021, 60, 25445-25453. DOI: 10.1002/anie.202110748

(362) Chemical synthesis of carbon nanorings and nanobelts
Yuanming Li, Hideya Kono, Takehisa Maekawa, Yasutomo Segawa, Akiko Yagi, Kenichiro Itami
Acc. Mater. Res. 2021, 2, 8, 681–691. https://pubs.acs.org/doi/10.1021/accountsmr.1c00105
Selected as a Cover.

(361) Photoredox-catalyzed benzylic esterification via radical-polar crossover
Bumpei Maeda, Yota Sakakibara, Kei Murakami, Kenichiro Itami
Org. Lett. 2021, 23, 5113-5117.

(360) Diversity-oriented synthesis of nanographenes enabled by dearomative annulative π-extension
Wataru Matsuoka, Hideto Ito, David Sarlah, Kenichiro Itami
Nature Commun. 2021, 12, 3940. DOI: 10.1038/s41467-021-24261-y [detail]
Highlighted in Chunichi Shimbun, Phys.org, Bioengineer.org, Nanowerk, Azom.com, Azonano, Science Daily

(359) Reversible modulation of circadian time with chronophotopharmacology
Dušan Kolarski, Carla Miró-Vinyals, Akiko Sugiyama, Ashutosh Srivastava, Daisuke Ono, Yoshiko Nagai, Mui Iida, Kenichiro Itami, Florence Tama, Wiktor Szymanski, Tsuyoshi Hirota, Ben L. Feringa
Nature Commun. 2021, 12, 3164. DOI: 10.1038/s41467-021-23301-x
Highlighted in Nature Commun., C&EN (ACS), Scitech Daily, Phys.org, ScienMag, infosurhoy, Bioengineer.org, AZO Life Sciences, ScienceNewsNet, Science Daily, The Medical News, Wikipedia (2021 in science)

(358) Synthesis and properties of helically-folded poly(arylenediethynylene)s
Michihisa Toya, Hideto Ito, Kenichiro Itami
Polym. Chem. 2021, 12, 3290-3298. [detail] DOI: 10.1039/D1PY00144B

(357) Construction of heptagon-containing molecular nanocarbons
Chaolumen, Iain A. Stepek, Keigo E. Yamada, Hideto Ito, Kenichiro Itami
Angew. Chem. Int. Ed. 2021, 60, 23508-23532. https://doi.org/10.1002/anie.202100260 [detail]

(356) Photo-induced arylation of carbazoles with aryldiazonium salts
Bumpei Maeda, Genki Mori, Yota Sakakibara, Akiko Yagi, Kei Murakami, Kenichiro Itami
Asian J. Org. Chem. 2021, 10, 1428-1431.

(355) Double-helix supramolecular nanofibers assembled from negatively curved nanographenes
Kenta Kato, Kiyofumi Takaba, Saori Maki-Yonekura, Nobuhiko Mitoma, Yusuke Nakanishi, Taishi Nishihara, Taito Hatakeyama, Takuma Kawada, Yuh Hijikata, Jenny Pirillo, Lawrence T. Scott, Koji Yonekura, Yasutomo Segawa, Kenichiro Itami
J. Am. Chem. Soc. 2021, 143, 5465-5469. DOI: 10.1021/jacs.1c00863
Selected as Cover.
Highlighted in Science, Nanotechnology Now, ScienMag, Bioengineer.org, Nanowerk.
ChemRxiv 2020, DOI: 10.26434/chemrxiv.13270607.v1

(354) Reductive stability evaluation of 6-azopurine photoswitches for the regulation of CKIα activity and circadian rhythm
Dušan Kolarski, Akiko Sugiyama, Theo Rodat, Albert Schulte, Christian Peifer, Kenichiro Itami, Tsuyoshi Hirota, Ben L. Feringa, Wiktor Szymanski
Org. Biomol. Chem. 2021, 19, 2312-2321.

(353) Synthesis of a zigzag carbon nanobelt
Kwan Yin Cheung, Kosuke Watanabe, Yasutomo Segawa, Kenichiro Itami
Nature Chem. 2021, 13, 255-259. https://www.nature.com/articles/s41557-020-00627-5
Highlighted in Nature Chem. and Synfatcs.
Highlighted in EurekAlert!, Bioengineer.org, ScienMag, Nanowerk, Phys.org, Azonano, Science Bulletin.
ChemRxiv, DOI 10.26434/chemrxiv.12324353.v2.

(352) Photopharmacological manipulation of mammalian CRY1 for regulation of the circadian clock
Dušan Kolarski, Simon Miller, Tsuyoshi Oshima, Yoshiko Nagai, Yugo Aoki, Piermichele Kobauri, Ashutosh Srivastava, Akiko Sugiyama, Kazuma Amaike, Ayato Sato, Florence Tama, Wiktor Szymanski, Ben Feringa, Kenichiro Itami, Tsuyoshi Hirota
J. Am. Chem. Soc. 2021, 143, 2078-2087. DOI: 10.1021/jacs.0c12280
Highlighted in Bionity, Naked Science, The Medical News.

(351) Exciton spatial dynamics and self-trapping in carbon nanocages
Beatriz Rodríguez-Hernández, Tammie Nelson, Nicolas Oldani, Aliezer Martínez-Mesa, Llinersy Uranga-Piña, Yasutomo Segawa, Sergei Tretiak, Kenichiro Itami, Sebastian Fernandez-Alberti
J. Phys. Chem. Lett. 2021, 12, 224-231.

(350) A theoretical study on the strain energy of helicene-containing carbon nanobelts
Kosuke Watanabe, Yasutomo Segawa, Kenichiro Itami
Chem. Commun. 2020, 56, 15044-15047. DOI: 10.1039/D0CC06373H

(349) Development of potent inhibitors for strigolactone receptor DWARF 14
Masahiko Yoshimura, Sojung F. Kim, Ryosuke Takise, Shuhei Kusano, Sakuya Nakamura, Masanori Izumi, Akiko Yagi, Kenichiro Itami, Shinya Hagihara
Chem. Commun. 2020, 56, 14917-14919. DOI: 10.1039/d0cc01989e

(348) Small molecules modulating mammalian biological clocks: Exciting new opportunities for synthetic chemistry
Kazuma Amaike, Tsuyoshi Oshima, Nicola Stephanie Skoulding, Yoshifumi Toyama, Tsuyoshi Hirota, Kenichiro Itami
Chem 2020, 6, 2186-2198. DOI: 10.1016/j.chempr.2020.08.011

(347) A N-terminally deleted form of the CK2a’ catalytic subunit is sufficient to support cell viability
Christian Borgo, Claudio D’Amore, Luca Cesaro, Kenichiro Itami, Tsuyoshi Hirota, Mauro Salvi, Lorenzo A. Pinna
Biochem. Biophys. Res. Commun. 2020, 531, 409-415. DOI: 10.1016/j.bbrc.2020.07.112

(346) “Janus” efficacy of CX-5011: CK2 inhibition and methuosis induction by independent mechanisms
Claudio D’Amore, Enrico Moro, Christian Borgo, Kenichiro Itami, Tsuyoshi Hirota, Lorenzo A. Pinna, Mauro Salvi
Biochem. Biophys. Acta. Mol. Cell Res. 2020, 1867, 118807.

(345) The prospects of Excellence Initiatives in research: Key ingredients for a successful academic research institute
Wolf B. Frommer, Kenichiro Itami
EMBO Reports 2020, e51398. DOI: 10.15252/embr.202051398

(344) Creation of negatively curved polyaromatics enabled by annulative coupling that forms an eight-membered ring
Satoshi Matsubara, Yoshito Koga, Yasutomo Segawa, Kei Murakami, Kenichiro Itami
Nature Catal. 2020, 3, 710-718. DOI: 10.1038/s41929-020-0487-0
Highlighted in ScienMag, Nanowerk, Phys.org, Science Daily, Chem-Station.

(343) Recent advances in C-H activation for the synthesis of π-extended materials
Iain A. Stepek, Kenichiro Itami
ACS Mater. Lett. 2020, 2, 951-974. DOI:10.1021/acsmaterialslett.0c00206

(342) Synthetic strategies of carbon nanobelts and related belt‐shaped polycyclic aromatic hydrocarbons
Kwan Yin Cheun, Yasutomo Segawa, Kenichiro Itami
Chem. Eur. J. 2020, 26, 14791-14801. DOI: 10.1002/chem.202002316

(341) A nonalternant aromatic belt: Methylene-bridged [6]cycloparaphenylene synthesized from pillar[6]arene
Yuanming Li, Yasutomo Segawa, Akiko Yagi, Kenichiro Itami
J. Am. Chem. Soc. 2020, 142, 12850-12856. DOI:10.1021/jacs.0c06007
ChemRxiv 2020, DOI: 10.26434/chemrxiv.12415166.v1

(340) Synthesis of cycloiptycenes from carbon nanobelt
Hiroki Shudo, Motonobu Kuwayama,Yasutomo Segawa, Kenichiro Itami
Chem. Sci. 2020, 11, 6775-6779. DOI: 10.1039/D0SC02501A
Highlighted in Chemistry World. Highlighted in ChemistryViews.

(339) An isoform-selective modulator of Cryptochrome 1 regulates circadian rhythms in mammals
Simon Miller, Yoshiki Aikawa, Akiko Sugiyama, Yoshiko Nagai, Aya Hara, Tsuyoshi Oshima, Kazuma Amaike, Steve A. Kay, Kenichiro Itami, Tsuyoshi Hirota
Cell Chem. Biol. 2020, 27, 1192-1198. DOI: 10.1016/j.chembiol.2020.05.008

(338) Molecular nanocarbon science: present and future
Kenichiro Itami, Takehisa Maekawa
Nano Lett. 2020, 20, 4718-4720. DOI: 10.1021/acs.nanolett.0c02143

(337) σ-Bond hydroboration of cyclopropanes
Hiroki Kondo, Shin Miyamura, Kaoru Matsushita, Hiroki Kato, Chisa Kobayashi, Arifin, Kenichiro Itami, Daisuke Yokogawa, Junichiro Yamaguchi
J. Am. Chem. Soc. 2020, 142, 11306-11313. DOI: 10.1021/jacs.0c05213
Highlighted in newspapers.

(336) Programmable synthesis of multiply arylated cubanes through C-H metalation and arylation
Ryo Okude, Genki Mori, Akiko Yagi, Kenichiro Itami
Chem. Sci. 2020, 11, 7672-7675. DOI:10.1039/D0SC01909G
The 10^th Anniversary Issue.
Highlighted in Chemistry World, ChemistryViews, and Synfacts.

(335) Synthesis of polybenzoacenes: Annulative dimerization of phenylene triflate by twofold C-H activation
Mizuho Uryu, Taito Hiraga, Yoshito Koga, Yutaro Saito, Kei Murakami, Kenichiro Itami
Angew. Chem. Int. Ed. 2020, 59, 6551-6554. DOI: 10.1002/ange.202001211
Selected as VIP paper. Selected as Cover of the journal. Highlighted in ChemistryViews.

(334) Isoform-selective regulation of mammalian cryptochromes
Simon Miller, You Lee Son, Yoshiki Aikawa, Eri Makino, Yoshiko Nagai, Ashutosh Srivastava, Tsuyoshi Oshima, Akiko Sugiyama, Aya Hara, Kazuhiro Abe, Kunio Hirata, Shinya Oishi, Shinya Hagihara, Ayato Sato, Florence Tama, Kenichiro Itami, Steve A. Kay, Megumi Hatori, Tsuyoshi Hirota
Nature Chem. Biol. 2020, 16, 676-685. DOI: 10.1038/s41589-020-0505-1
Highlighted in Nature Chem. Biol.
Highlighted in Phys.org, Technology Networks, Drug Target Review, Galileonet, Neuroscience News Updates

(333) Selective transformation of strychnine and 1,2-disubstituted benzenes by C-H borylation
Yutaro Saito, Kotono Yamanoue, Yasutomo Segawa, Kenichiro Itami
Chem 2020, 6, 985-993. DOI: 10.1016/j.chempr.2020.02.004

(332) Six-fold C-H borylation of hexa-peri-hexabenzocoronene
Mai Nagase, Kenta Kato, Akiko Yagi, Yasutomo Segawa, Kenichiro Itami
Beilstein J. Org. Chem. 2020, 16, 391-397. DOI: 10.3762/bjoc.16.37
Thematic issue on “C-H functionalization for materials science”.

(331) Rapid access to kinase inhibitor pharmacophore by regioselective C-H arylation of thieno[2,3-d]pyrimidine
Shuya Yamada, Kaylin Nicole Flesch, Kei Murakami, Kenichiro Itami
Org. Lett. 2020, 22, 1547-1551. DOI: 10.1021/acs.orglett.0c00143

(330) Roles of base in the Pd-catalyzed annulative chlorophenylene dimerization
Li-Ping Xu, Brandon E. Haines, Manjaly J. Ajitha, Kei Murakami, Kenichiro Itami, Djamaladdin G. Musaev
ACS Catal. 2020, 10, 3059-3073. DOI: 10.1021/acscatal.9b05328

(329) Synthesis of nitrogen-containing polyaromatics by aza-annulative π-extension of unfunctionalized aromatics
Kou P. Kawahara, Wataru Matsuoka, Hideto Ito, Kenichiro Itami
Angew. Chem. Int. Ed. 2020, 59, 6383-6388. DOI: 10.1002/anie.201913394

(328) Synthesis of highly twisted, nonplanar aromatic macrocycles enabled by axially chiral 4,5-diphenylphenanthrene building block
Yuanming Li, Akiko Yagi, Kenichiro Itami
J. Am. Chem. Soc. 2020, 142, 3246-3253. DOI: 10.1021/jacs.9b13549

(327) Synthesis and structure of [9]cycloparaphenylene catenane: An all-benzene catenane consisting of small rings
Yasutomo Segawa, Motonobu Kuwayama, Kenichiro Itami
Org. Lett. 2020, 22, 1067-1070. DOI: 10.1021/acs.orglett.9b04599

(326) Toward uncaptured and passionate research
Kenichiro Itami
Chemistry & Chemical Industry 2020, 73, 5-6.

(325) A quest for structurally uniform graphene nanoribbons: synthesis, properties, and applications
Yuuta Yano, Nobuhiko Mitoma, Hideto Ito, Kenichiro Itami
J. Org. Chem. 2020, 85, 4-33. DOI: 10.1021/acs.joc.9b02814

(324) Topologically unique molecular nanocarbons
Yasutomo Segawa, David R. Levine, Kenichiro Itami
Acc. Chem. Res. 2019, 52, 2760-2767. DOI: 10.1021/acs.accounts.9b00402
Special issue on “Advanced Molecular Nanocarbons”.

(323) Controlling the circadian clock with high temporal resolution through photodosing
Dušan Kolarski, Akiko Sugiyama, Ghislain Breton, Christin Rakers, Daisuke Ono, Albert Schulte, Florence Tama, Kenichiro Itami, Wiktor Szymanski, Tsuyoshi Hirota, Ben L. Feringa
J. Am. Chem. Soc. 2019, 141, 15784-15791.
Highlighted in various media.

(322) Two-step synthesis of a red-emissive warped nanographene derivative via a ten-fold C-H borylation
Kenta Kato, Hsing-An Lin, Motonobu Kuwayama, Mai Nagase, Yasutomo Segawa, Lawrence T. Scott, Kenichiro Itami
Chem. Sci. 2019, 10, 9038-9041.

(321) Negatively-curved warped nanographene self-assembled on metal surfaces
José I. Urgel, Marco Di Giovannantonio, Yasutomo Segawa, Pascal Ruffieux, Lawrence T. Scott, Carlo A. Pignedoli, Kenichiro Itami, Roman Fasel
J. Am. Chem. Soc. 2019, 141, 13158-13164.

(320) Topological molecular nanocarbons: all-benzene catenane and trefoil knot
Yasutomo Segawa, Motonobu Kuwayama, Yuh Hijikata, Masako Fushimi, Taishi Nishihara, Jenny Pirillo, Junya Shirasaki, Natsumi Kubota, Kenichiro Itami
Science 2019, 365, 272-276. https://www.science.org/doi/10.1126/science.aav5021
Selected as the Molecule of the Year (ACS).
Highlighted in Science, C&E News, and many other newspapers.

(319) An axially chiral 1,1′-biazulene and its π-extended derivative: synthesis, structures and properties
Chaolumen, Hideto Ito, Kenichiro Itami
Chem. Commun. 2019, 55, 9606-9609. DOI: 10.1039/C9CC03510A【detail】
Selected as a front cover in volume 55, issume 65.

(318) Strength of carbon nanotubes depends on their chemical structures
Akira Takakura, Ko Beppu, Taishi Nishihara, Akihito Fukui, Takahiro Kozeki, Takahiro Namazu, Yuhei Miyauchi, Kenichiro Itami
Nature Commun. 2019, 10, 3040. https://www.nature.com/articles/s41467-019-10959-7
Highlighted in Nanowerk, Lab Manager, Phys.org, PBS, and many newspapers.

(317) Casein kinase 1 family regulates PRR5 and TOC1 in the Arabidopsis circadian clock
Takahiro N. Uehara, Yoshiyuki Mizutani, Keiko Kuwata, Tsuyoshi Hirota, Ayato Sato, Junya Mizoi, Saori Takao, Hiromi Matsuo, Takamasa Suzuki, Shogo Ito, Ami N Saito, Taeko Nishiwaki-Ohkawa, Kazuka Yamaguchi-Shinozaki, Takashi Yoshimura, Steve Kay, Kenichiro Itami, Toshinori Kinoshita, Junichiro Yamaguchi, Norihito Nakamichi
Proc. Nat. Acad. Sci. 2019, 116, 11528-11536. DOI:10.1073/pnas.1903357116 [detail]
Highlighted in many newspapers.

(316) A unique ultra-narrow-band thermal exciton radiation phenomena of carbon nanotubes
Taishi Nishihara, Akira Takakura, Yuhei Miyauchi, Kenichiro Itami
Technical Information Institute Magazine 2019, 361-369.

(315) Synthesis of polycyclic aromatic compunds by direct coupling
Wataru Matsuoka, Hideto Ito, Kenichiro Itami
Design and Applications of Direct Aromatic Coupling Reactions
CMC Press, Chapter 12, 136-148.

(314) Synthesis of sterically hindered 4,5-diarylphenanthrenes via acid-catalyzed bisannulation of benzenediacetaldehydes with alkynes
Yuanming Li, Akiko Yagi, Kenichiro Itami
Chem. Sci. 2019, 10, 5470-5475. DOI:10.1039/c9sc00334g
Selected as 2019 Chemical Science HOT Article.

(313) Armchair and chiral carbon nanobelts: Scholl reaction in strained nanorings
Akiko Yagi, Yasutomo Segawa, Kenichiro Itami
Chem 2019, 5, 746-748.

(312) Dehydrogenative synthesis of 2,2′-bipyridyls through regioselective pyridine dimerization
Shuya Yamada, Takeshi Kaneda, Philip Steib, Kei Murakami, Kenichiro Itami
Angew. Chem. Int. Ed. 2019, 58, 8341-8345. DOI:10.1002/anie.201814701.【detail】

(311) Bay-region selective annulative π-extension (APEX) of perylene diimides with arynes
Takayuki Nakamuro, Kazushi Kumazawa, Hideto Ito, Kenichiro Itami
Synlett 2019, 30, 423-428. DOI: 10.1055/s-0037-1611668.

(310) Synthesis and structural features of thiophene-fused analogues of warped nanographene and quintuple helicene
Hsing-An Lin, Kenta Kato, Yasutomo Segawa, Lawrence T. Scott, Kenichiro Itami
Chem. Sci. 2019, 10, 2326-2330. DOI: 10.1039/C8SC04470H

(309) Ultra-narrow-band thermal exciton radiation phenomena of carbon nanotubes
Taishi Nishihara, Akira Takakura, Kenichiro Itami, Yuhei Miyauchi
Clean Energy 2019, 28, 7-14.

(308) Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth
Tsuyoshi Oshima, Yoshimi Niwa, Keiko Kuwata, Ashutosh Srivastava, Tomoko Hyoda, Yoshiki Tsuchiya, Megumi Kumagai, Masato Tsuyuguchi, Teruya Tamaru, Akiko Sugiyama, Natsuko Ono, Norjin Zolboot, Yoshiki Aikawa, Shunsuke Oishi, Atsushi Nonami, Fumio Arai, Shinya Hagihara, Junichiro Yamaguchi, Florence Tama, Yuya Kunisaki, Kazuhiro Yagita, Masaaki Ikeda, Takayoshi Kinoshita, Steve A. Kay, Kenichiro Itami, Tsuyoshi Hirota
Science Adv. 2019, 5, eau9060. DOI: 10.1126/sciadv.aau9060
Highlighted in Jamaice Observer, Xinhua, Cooperative, Health Canal, China.org, Drug Discoverry and Development, R&D, Technology Networks, ecancer, Science Daily, MidicalXpress, EurekAleet!.

(307) Polycyclic arene synthesis by annulative π-extension
Hideto Ito, Yasutomo Segawa, Kei Murakami, Kenichiro Itami
J. Am. Chem. Soc. 2019, 141, 3-10. https://pubs.acs.org/doi/10.1021/jacs.8b09232

(306) New directions in natural product synthesis
Huw M. L. Davies, Kenichiro Itami, Brian M. Stoltz
Chem. Soc. Rev. 2018, 47, 7828-7829.

(305) Dissecting plant hormone signaling with synthetic molecules: perspective from the chemists
Shinya Hagihara, Ryotaro Yamada, Kenichiro Itami, Keiko U. Torii
Curr. Opin. Plant Biol. 2018, 47, 32-37.

(304) Discovery of plant growth stimulants by C-H arylation of 2-azahypoxanthine
Hiroyuki Kitano, Jae-Hoon Choi, Ayaka Ueda, Hideto Ito, Shinya Hagihara, Toshiyuki Kan, Hirokazu Kawagishi, Kenichiro Itami
Org. Lett. 2018, 20, 5684-5687. DOI: 10.1021/acs.orglett.8b02363 【detail】
Highlighted in C&E News (ACS).

(303) Symmetric multiple carbohelicenes
Kenta Kato, Yasutomo Segawa, Kenichiro Itami
Synlett 2019, 30, 370-377. DOI: 10.1055/s-0037-1610283

(302) Ultra-narrow-band near-infrared thermal exciton radiation in intrinsic one-dimensional semiconductors
Taishi Nishihara, Akira Takakura, Yuhei Miyauchi, Kenichiro Itami
Nature Commun.2018, 9, 3144. https://www.nature.com/articles/s41467-018-05598-3 [press release] [detail]

(301) Annulative π-Extension of Indoles and Pyrroles with Diiodobiaryls by Pd Catalysis: Rapid Synthesis of Nitrogen-Containing Polycyclic Aromatic Compounds
Hiroyuki Kitano, Wataru Matsuoka, Hideto Ito, Kenichiro Itami
Chem. Sci. 2018, 9, 7556-7561.【detail】

(300) Synthesis and Size-Dependent Properties of [12], [16], and [24]Carbon Nanobelts
Guillaume Povie, Yasutomo Segawa, Taishi Nishihara, Yuhei Miyauchi, Kenichiro Itami
J. Am. Chem. Soc. 2018, 140, 10054-10059. DOI: 10.1021/jacs.8b06842 【detail】

(299) Carbon Nanosheets by Morphology-Retained Carbonization of Two-Dimensional Assembled Anisotropic Carbon Nanorings
Taizo Mori, Hiroyuki Tanaka, Amit Dalui, Nobuhiko Mitoma, Kengo Suzuki, Mutsuyoshi Matsumoto, Nikhil Aggarwal, Archita Patnaik, Somobrata Acharya, Lok Kumar Shrestha, Hirotoshi Sakamoto, Kenichiro Itami, Katsuhiko Ariga
Angew. Chem. Int. Ed. 2018, 57, 9679-9683. DOI: 10.1002/anie.201803859 [detail]
Selected as Hot Paper.

(298) Gold-Catalyzed C-H Imidation of Polycyclic Aromatic Hydrocarbons
Yip Shu Jan, Takahiro Kawakami, Kei Murakami, Kenichiro Itami
Asian J. Org. Chem. 2018, 7, 1372-1375. DOI: 10.1002/ajoc.201800293. 【detail】

(297) Modular Synthesis of Heptaarylindole
Shin Suzuki, Kenichiro Itami, Kei Muto, Junichiro Yamaguchi
Org. Biol. Chem. 2018,16, 3771-3776. DOI: 10.1039/C8OB00993G

(296) Synthesis of Heptaarylisoquinolines: Unusual Disconnection for Constructing Isoquinoline Frameworks
Takashi Asako, Shin Suzuki, Kenichiro Itami, Kei Muto, Junichiro Yamaguchi
Chem. Lett. 2018, 47, 968-970. DOI: 10.1246/cl.180429 [detail]

(295) Pd-Catalyzed Decarbonylative C-H Coupling of Azoles and Aromatic Esters
Kaoru Matsushita, Ryosuke Takise, Tomoya Hisada, Shin Suzuki, Ryota Isshiki, Kenichiro Itami, Kei Muto, Junichiro Yamaguchi
Chem. Asian J. 2018, 13, 2393-2396. DOI: 10.1002/asia.201800478

(294) Late-Stage Functionalization of Arylacetic Acids by Photoredox-Catalyzed Decarboxylative Carbon–Heteroatom Bond Formation
Yota Sakakibara, Eri Ito, Tomohiro Fukushima, Kei Murakami, Kenichiro Itami
Chem. Eur. J. 2018, 24, 9254-9258. DOI:10.1002/chem.201802143.【detail 】

(293) A super strong engineered auxin-TIR1 pair
Ryotaro Yamada, Keiichiro Murai, Naoyuki Uchida, Koji Takahashi, Rie Iwasaki, Yasuomi Tada, Toshinori Kinoshita, Kenichiro Itami, Keiko U. Torii, Shinya Hagihara
Plant Cell Physiol. 2018, 59, 1538-1544. DOI: 10.1093/pcp/pcy127. [Detail]

(292) Photoredox-Catalyzed Decarboxylative Oxidation of Arylacetic Acids
Yota Sakakibara, Phillippa Cooper, Kei Murakami, Kenichiro Itami
Chem. Asian J. 2018, 13, 2410-2413. DOI:10.1002/asia.201800529.【detail】

(291) Merging synthetic chemistry with plant biology and chronobiology for creating transformative molecules
Kenichiro Itami, Shinya Hagihara, Ayato Sato
Medchem News 2018, 28, 1-7.

(290) Palladium-Catalyzed Esterification of Carboxylic Acids with Aryl Iodides
Hiroyuki Kitano, Hideto Ito, Kenichiro Itami
Org. Lett. 2018, 20, 2428-2432. DOI: 10.1021/acs.orglett.8b00775 【detail】
Highlighted as Most read articles (7th May, 2018)

(289) Synthesis and Structure of a Propeller-Shaped Polycyclic Aromatic Hydrocarbon Containing Seven-Membered Rings
Kazuya Kawai, Kenta Kato, Lingqing Peng, Yasutomo Segawa, Lawrence T. Scott, Kenichiro Itami
Org. Lett. 2018, 20, 1932-1935. DOI: 10.1021/acs.orglett.8b00477 【detail】

(288) Recent advances in acetylene-based helical oligomers and polymers: Synthesis, structures, and properties
Michihisa Toya, Hideto Ito, Kenichiro Itami
Tetrahedron Lett. 2018, 59, 1531-1547. DOI: 10.1016/j.tetlet.2018.03.018 【detail】

(287) A Water-soluble Warped Nanographene: Synthesis and Applications for Photo-induced Cell Death
Hsing-An Lin, Yoshikatsu Sato, Yasutomo Segawa, Taishi Nishihara, Nagisa Sugimoto, Lawrence T. Scott, Tetsuya Higashiyama, Kenichiro Itami
Angew. Chem. Int. Ed. 2018, 57, 2874-2878. DOI: 10.1002/anie.201713387 【detail】
Selected as VIP Paper.
Highlighted in Nikkei Shimbun, Asia Research News, KEXMY, Phys Org, Science Daily, Science Newsline, WILEY, NEWS MEDICAL LIFE SCIENCES, BioSpectrum, SPACE DAILY, fabcross, Photonics.com, Controlled Environments, Azonano, The Medical News.

(286) Discovery of Shoot Branching Regulator Targeting Strigolactone Receptor DWARF14
Masahiko Yoshimura, Ayato Sato, Keiko Kuwata, Yoshiaki Inukai, Toshinori Kinoshita, Kenichiro Itami, Yuichiro Tsuchiya, Shinya Hagihara
ACS Cent. Sci. 2018, 4, 230-234. DOI: 10.1021/acscentsci.7b00554【detail】
Highlighted in SeedQuest, Phys.org, EurekAlert!.

(285) Unidirectional molecular assembly alignment on graphene enabled by nanomechanical symmetry breaking
Liu Hong, Taishi Nishihara, Yuh Hijikata, Yuhei Miyauchi, Kenichiro Itami
Sci. Rep. 2018, 2333.
Selected as Top 100 papers. Highlighted in OPTRONICS, Research in Japan.

(284) C-H Arylation of Phenanthrene with Trimethylphenylsilane by Pd/o-Chloranil Catalysis: Computational Studies on the Mechanism, Regioselectivity, and Role of o-Chloranil
Mari Shibata, Hideto Ito, Kenichiro Itami
J. Am. Chem. Soc. 2018, 140, 2196-2205. DOI: 10.1021/jacs.7b11260【detail】

(283) Design, synthesis and evaluation of γ-turn mimetics as LSD1-selective inhibitors
Yosuke Ota, Shin Miyamura, Misaho Araki, Yukihiro Itoh, Shusuke Yasuda, Mitsuharu Masuda, Tomoyuki Taniguchi, Yoshihiro Sowa, Toshiyuki Sakai, Kenichiro Itami, Junichiro Yamaguchi, Takayoshi Suzuki
Bioorg. Med. Chem. 2018, 26, 775-785.

(282) Synthesis of partially and fully fused polyaromatics by annulative chlorophenylene dimerization
Yoshito Koga, Takeshi Kaneda, Yutaro Saito, Kei Murakami, Kenichiro Itami
Science 2018, 359, 435-439. DOI: 10.1126/science.aap9801【detail】
Highlighted in Chunichi Shimbun, NHK, NIKKAN KOGYO SHIMBUN, Asahi Shimbun, Nikkei Shimbun, C&EN, Kagaku Shimbun etc.

(281) Chemical hijacking of auxin signaling with an engineered auxin–TIR1 pair
Naoyuki Uchida, Koji Takahashi, Rie Iwasaki, Ryotaro Yamada, Masahiko Yoshimura, Takaho A Endo, Seisuke Kimura, Hua Zhang, Mika Nomoto, Yasuomi Tada, Toshinori Kinoshita, Kenichiro Itami, Shinya Hagihara, Keiko U Torii
Nature Chem. Biol. 2018, 14, 299-305. DOI: 10.1038/nchembio.2555【detail】プレスリリース（日本語）
Highlighted in Mainichi Shimbun, Crop Biotech Update, Earth.com, Science Newsline Biology

(280) A Quintuple [6]Helicene with a Corannulene Core as a C5-symmetric Propeller-shaped π-System
Kenta Kato, Yasutomo Segawa, Lawrence T. Scott, Kenichiro Itami
Angew. Chem. Int. Ed. 2018, 57, 1337-1341. DOI: 10.1002/anie.201711985 【detail】
Selected as Hot Paper.
Highlighted in Photonics.com, Controlled Environments, Azonano, Long Room.

(279) Synthesis of α-Fluoroimines by Copper-Catalyzed Reaction of Diarylacetylenes and N-Fluorobenzenesulfonimide
Shu Jan Yip, Tetsushi Yoshidomi, Kei Murakami, Kenichiro Itami
Chem. Lett. 2018, 47, 329-331. DOI: https://doi.org/10.1246/cl.171097 【detail】

(278) Hole-transporting materials based on thiophene-fused arenes from sulfur-mediated thienannulations
Lin Hsing-An, Nobuhiko Mitoma, Meng Lingkui, Yasutomo Segawa, Atsushi Wakamiya, Kenichiro Itami
Mater. Chem. Front. 2018, 2, 275-280. DOI: 10.1039/C7QM00473G

(277) Synthesis of Octaaryl Naphthalenes and Anthracenes with Different Substituents
Shin Suzuki, Kenichiro Itami, Junichiro Yamaguchi
Angew. Chem. Int. Ed. 2017, 56, 15010-15013DOI: 10.1002/anie.201709332.【detail】

(276) Catalytic alpha-Arylation of Ketones with Heteroaromatic Esters
Ryota Isshiki, Ryosuke Takise, Kenichiro Itami, Kei Muto, Junichiro Yamaguchi
Synlett 2017, 28, 2599-2603.

(275) Oxidative Homocoupling Reaction of Aryltrimethylsilanes by Pd/o-chloranil Catalysis
Mari Shibata, Hideto Ito, Kenichiro Itami
Chem. Lett. 2017, 46, 1701-1704. DOI: 10.1246/cl.170723.【detail】
Dedicated issue to the late Prof. Yoshihiko Ito.

(274) Discovery of synthetic small molecules that enhance the number of stomata: C–H functionalization chemistry for plant biology
Asraa Ziadi, Naoyuki Uchida, Hiroe Kato, Rina Hisamatsu, Ayato Sato, Shinya Hagihara, Kenichiro Itami, Keiko U. Torii
Chem. Commun. 2017, 53, 9632-9635. DOI:10.1039/C7CC04526C.
Highlighted in Chemical & Engineering News (ACS), Alpha Galileo, ResearchSEA, EurekAlert!, Phys.Org, SeedQuest, Science Daily, Mihan Magazine, Bioengineer, Health Medicine Network, Asian Scientist.

(273) Rapid Access to Nanographenes and Fused Heteroaromatics by Palladium-Catalyzed Annulative π-Extension Reaction of Unfunctionalized Aromatics with Diiodobiaryls
Wataru Matsuoka, Hideto Ito, Kenichiro Itami
Angew. Chem. Int. Ed. 2017, 56, 12224-12228.DOI: 10.1002/anie.201707486 【detail】
Highlighted in Organometallic Chemistry: Current Trends in Organometallic and Synthetic Chemistry

(272) Laterally π-Extended Dithia[6]helicenes with Heptagons: Saddle-Helix Hybrid Molecules
Takao Fujikawa, Yasutomo Segawa, Kenichiro Itami
J. Org. Chem. 2017, 82, 7745-7749. DOI: 10.1021/acs.joc.7b01540 【detail】

(271) Aromatic C-H amination: a radical approach for adding new functions into biology- and materials-oriented aromatics
Kei Murakami, Gregory J. P. Perry, Kenichiro Itami
Org. Biomol. Chem. 2017, 15, 6071-6075. DOI: 10.1039/C7OB00985B

(270) Dramatic history behind the first synthesis of a carbon nanobelt (an account in Japanese)
Kenichiro Itami, Yasutomo Segawa, Haruka Omachi, Akiko Yagi
Kagaku 2017, 72, 23-31.

(269) Strigolactone receptors in Striga hermonthica
Masahiko Yoshimura, Yuichiro Tsuchiya, Yoshikatsu Sato, Kenichiro Itami, Toshinori Kinoshita, Shinya Hagihara
Plant Morphology 2017, 29, 33-37. DOI:【detail】

(268) Synthesis of a carbon nanobelt (an account in Japanese)
Yasutomo Segawa, Kenichiro Itami
Chemistry Today 2017, 556, 36-39.

(267) Electrically Activated Conductivity and White Light Emission of a Hydrocarbon Nanoring-Iodine Assembly
Noriaki Ozaki, Hirotoshi Sakamoto, Taishi Nishihara, Toshihiko Fujimori, Yuh Hijikata, Ryuto Kimura, Stephan Irle, Kenichiro Itami
Angew. Chem. Int. Ed. 2017, 56, 11196-11202. DOI: 10.1002/anie.201703648 【detail】
Selected as Frontispiece and Hot Paper.
Featured in Chunichi Shimbun, Nikkan Kogyo Shimbun, Kagaku Shimbun, Nikkei Shimbun, AlphaGalileo, Ansa, Asian Scientist, Azo Materials, Controlled Environments, Corriere, Tecnologie, EurekAlert!, Fanpage, Global Info Research, INOVACAO tecnologica, Nanotechnology Now, Nanotechweb, Nanowerk, Novus Light, Phys.Org, Poltivesti, R&D Magazine, ResearchSEA, RevoScience, Science Blog, Science Daily, Science Newsline, Space Daily, Chem-Station, BIO IMPACT, J-Net21, JPubb, JST, livedoornews, Nanotech Japan, OPTRONICS, Spring8.

(266) Annulative π-Extension (APEX): An Enabling Reaction for Rapid Access to Fused Aromatics, Heteroaromatics, and Nanographenes
Hideto Ito, Kyohei Ozaki, Kenichiro Itami
Angew. Chem. Int. Ed. 2017, 56, 11144-11164. DOI: 10.1002/anie.201701058.【detail】

(265) Thiazole-based s₁ receptor ligands: Diversity by Late-stage C-H Arylation of Thiazoles, Structure Affinity and Selectivity Relationships and Molecular Interactions
Artur Kokornaczyk, Dirk Schepmann, Junichiro Yamaguchi, Kenichiro Itami, Erik Laurini, Maurizio Fermeglia, Sabrina Pricl, Bernhard Wünsch
ChemMedChem. 2017, 12, 1070-1080.

(264) Synthesis, Properties, and Crystal Structures of π-Extended Double [6]Helicenes: Contorted Multi-Dimensional Stacking Lattice
Takao Fujikawa, Nobuhiko Mitoma, Atsushi Wakamiya, Akinori Saeki, Yasutomo Segawa, Kenichiro Itami
Org. Biomol. Chem. 2017, 15, 4697-4703. DOI: 10.1039/C7OB00987A 【detail】

(263) Theoretical Elucidation of Potential Enantioselectivity in a Pd-Catalyzed Aromatic C-H Coupling Reaction
Yoshio Nishimoto, Hiroki Kondo, Kazuya Yamaguchi, Daisuke Yokogawa, Junichiro Yamaguchi, Kenichiro Itami, Stephan Irle
J. Org. Chem. 2017, 82, 4900-4906. DOI: 10.1021/acs.joc.6b02675

(262) Direct Coupling of Naphthalene and Sulfonimides Promoted by DDQ and Blue Light
Yota Sakakibara^†, Eri Ito^†, Takahiro Kawakami, Shuya Yamada, Kei Murakami, Kenichiro Itami (†Equal contribution)
Chem. Lett. 2017, 46, 1014-1016. DOI: http://dx.doi.org/10.1246/cl.170321

(261) C-H Functionalization of Azines
Kei Murakami, Shuya Yamada, Takeshi Kaneda, Kenichiro Itami
Chem. Rev. 2017, 117, 9302-9332. DOI: 10.1021/acs.chemrev.7b00021 【detail】

(260) Synthesis of a carbon nanobelt
Guillaume Povie, Yasutomo Segawa, Taishi Nishihara, Yuhei Miyauchi, Kenichiro Itami
Science 2017, 356, 172-175. DOI: 10.1126/science.aam8158 【detail】
Featured in TV (NHK, Fuji TV, Chukyo TV, CBC TV, Nagoya TV, Tokai TV), Nature, and Yahoo! News, Chunichi Shimbun, Asahi Shimbun, Yomiuri Shimbun, Mainichi Shimbun, Nikkei Shimbun, Nikkan Kogyo Shimbun, The Chemical Daily, Jiji Tsushin, Asahi Shogakusei Shimbun. Highlighted in Science, C&E News (ACS), Chemistry World (RSC), Synfacts, Chem, Physics Today, Angew. Chem. Int. Ed., Kagaku, Gendai Kagaku, Computational Chemistry Highlights, materialstoday, chembites, Chem-station, Asia Research News, BIGLOBE, BIONITY, CBC News, Compound Interest, Controlled Environments, EETimes Japan, Innovation Toronto.

(259) Annulative π-Extension (APEX) of Heteroarenes with Dibenzosiloles and Dibenzogermoles by Palladium/o-Chloranil Catalysis
Kyohei Ozaki, Wataru Matsuoka, Hideto Ito, Kenichiro Itami
Org. Lett. 2017, 19, 1930-1933. DOI: 10.1021/acs.orglett.7b00684【detail】

(258) Synthesis of Multiply Arylated Pyridines
Takashi Asako, Wakana Hayashi, Kazuma Amaike, Shin Suzuki, Kenichiro Itami, Kei Muto, Junichiro Yamaguchi
Tetrahedron 2017, 73, 3669-3676 (special Issue). DOI: 10.1016/j.tet.2017.03.095 【detail】

(257) Polymorphism of [6]cycloparaphenylene for packing structure-dependent host-guest interaction
Tomohiro Fukushima, Hirotoshi Sakamoto, Kohei Tanaka, Yuh Hijikata, Stephan Irle, Kenichiro Itami
Chem. Lett. 2017, 46, 855-857. DOI: 10.1246/cl.170210【detail】
Selected as Editor’s Choice.

(256) Rh-Catalyzed Regiodivergent Hydrosilylation of Acyl aminocyclopropanes Controlled by Monophosphine Ligands
Hiroki Kondo, Kenichiro Itami, Junichiro Yamaguchi
Chem. Sci. 2017, 8, 3799-3803. DOI: 10.1039/C7SC00071E【detail】

(255) Catalytic Dehydrogenative C–H Imidation of Arenes Enabled by Photo-generated Hole Donation to Sulfonimide
Eri Ito, Tomohiro Fukushima, Takahiro Kawakami, Kei Murakami, Kenichiro Itami
Chem (Cell Press) 2017, 2, 383-392. DOI: 10.1246/cl.170091 【detail】
Selected as Cover Picture. Highlighted in Chem-Station.

(254) Decarbonylative Diaryl Ether Synthesis by Pd and Ni Catalysis
Ryosuke Takise, Ryota Isshiki, Kei Muto, Kenichiro Itami, Junichiro Yamaguchi
J. Am. Chem. Soc. 2017, 139, 3340-3343.
Featured in newspapers (The Chemical Daily, Nikkei Sangyo Shimbun). Highlighted in Chem-Station, ScienceDaily, Phys.org. Most read ariticle (March 2017).

(253) Synthesis, Structure, and Electrochemical Property of a Bimetallic Bis-2-pyridylidene Palladium Acetate Complex
Tetsushi Yoshidomi, Tomohiro Fukushima, Kenichiro Itami, Yasutomo Segawa
Chem. Lett. 2017, 46, 587-590. DOI: 10.1246/cl.170091 【detail】

(252) Palladium-Catalyzed Decarbonylative Alkynylation of Aromatic Esters
Toshimasa Okita, Kazushi Kumazawa, Ryosuke Takise, Kei Muto, Kenichiro Itami, Junichiro Yamaguchi
Chem. Lett. 2017, 46, 218-220. DOI: http://dx.doi.org/10.1246/cl.161001.
Most read article (November-December 2016).

(251) Toward an Ideal Synthesis of (Bio)molecules through Direct Arene Assembling Reactions
Junichiro Yamaguchi, Kenichiro Itami
Bull. Chem. Soc. Jpn. 2017, 90, 367-383. DOI: http://dx.doi.org/10.1246/bcsj.20160365.
Selected as Back Cover. Most read article (December 2016).

(250) One-Step Annulative π-Extension of Alkynes with Dibenzosiloles or Dibenzogermoles by Palladium/o-chloranil Catalysis
Kyohei Ozaki, Keiichiro Murai, Wataru Matsuoka, Katsuaki Kawasumi, Hideto Ito, Kenichiro Itami
Angew. Chem. Int. Ed. 2017, 56, 1361-1364. DOI: 10.1002/anie.201610374【detail】
Selected as Hot Paper. Highlighted in Synfacts.

(249) Key Structural Elements of Unsymmetrical Cyanine Dyes for Highly Sensitive Fluorescence Turn-on DNA Probe
Kakishi Uno, Taeko Sasaki, Nagisa Sugimoto, Hideto Ito, Taishi Nishihara, Shinya Hagihara, Tetsuya Higashiyama, Narie Sasaki, Yoshikatsu Sato, Kenichiro Itami
Chem. Asian J. 2017, 12, 233-238. DOI: 10.1002/asia.201601430【detail】
Highlighted in chemistry views. Most accessed article in January 2017 (First Place)

(248) Synthesis, Structure, and Reactivity of a Cylinder-shaped Cyclo[12]orthophenylene[6]ethynylene: Toward the Synthesis of Zigzag Carbon Nanobelts
Katsuma Matsui, Masako Fushimi, Yasutomo Segawa, Kenichiro Itami
Org. Lett. 2016, 18, 5352-5355.
Highlighted in Synfacts.

(247) Syntheses of Biologically Active 2-Arylcyclopropylamines
Shin Miyamura, Kenichiro Itami, Junichiro Yamaguchi
Synthesis 2017, 49, 1131-1149. DOI: 10.1055/s-0036-1588390
Highlighted in Front Cover.

(246) Phenanthro[9,10-a]corannulene by One-step Annulative π-Extension of Corannulene
Kenta Kato, Yasutomo Segawa, Kenichiro Itami
Can. J. Chem. 2017, 95, 329-333.
Special issue to honor Professor Reginald Mitchell.

(245) Palladium-Catalyzed Decarbonylative Cross-Coupling of Azinecarboxylates with Arylboronic Acids
Kei Muto, Taito Hatakeyama, Kenichiro Itami, Junichiro Yamaguchi
Org. Lett. 2016, 18, 5106-5109. DOI: 10.1021/acs.orglett.6b02556【detail】

(244) Cu-Catalyzed aromatic C-H imidation with N-fluorobenzenesulfonimide: mechanistic details and predictive models
Brandon E. Haines, Takahiro Kawakami, Keiko Kuwata, Kei Murakami, Kenichiro Itami, Djamaladdin G. Musaev
Chem. Sci. 2017, 8, 998-1001. DOI: 10.1039/C6SC04145K【detail】
Highlighted in Chemical & Engineering News.

(243) Flexible Reaction Pocket on Bulky Diphosphine–Ir Complex Controls Regioselectivity in para-Selective C–H Borylation of Arenes
Brandon E. Haines, Yutaro Saito, Yasutomo Segawa, Kenichiro Itami, Djamaladdin G Musaev
ACS Catal. 2016, 6, 7536-7546. DOI: 10.1021/acscatal.6b02317【detail】

(242) (R)- and (S)-2,2’-Bis(3,5-dimethylphenylphosphino)-6,6’-dimethoxy-1,1’-biphenyl
Yutaro Saito, Yasutomo Segawa, Kenichiro Itami
Electronic Encyclopedia of Reagents for Organic Synthesis, Wiley, online.

(241) Structure-Activity Relation of AMOR Sugar Molecule that Activates Pollen-Tubes for Ovular Guidance
Jiao Jiao, Akane G. Mizukami, Subramanian Sankaranarayanan, Junichiro Yamaguchi, Kenichiro Itami, Tetsuya Higashiyama
Plant Physiology 2017, 173, 354-363. DOI: http://dx.doi.org/10.1104/pp.16.01655 .

(240) Synthesis and Properties of [8]-, [10]-, [12]-, and [16]Cyclo-1,4-naphthylenes
Keishu Okada, Akiko Yagi, Yasutomo Segawa, Kenichiro Itami
Chem. Sci. 2016, 8, 661–667. DOI: 10.1039/C6SC04048A【detail】

(239) Macrocyclization by Rh-Catalyzed Cross-Cyclotrimerization of L-Shaped Diynes with Di-tert-butyl Acetylenedicarboxylate: Effect of Bent Linkers of Diynes
Shuhei Nishigaki, Yuta Miyauchi, Keiichi Noguchi, Hideto Ito, Kenichiro Itami, Yu Shibata, Ken Tanaka
Eur. J. Org. Chem. 2016, 4668–4673. DOI: 10.1002/ejoc.201600909【detail】

(238) Nickel-Catalyzed Aromatic C–H Functionalization
Junichiro Yamaguchi, Kei Muto, Kenichiro Itami
Top. Curr. Chem. 2016, 374, 1. DOI: 10.1007/s41061-016-0053-z【detail】

(237) Construction of Covalent Organic Nanotubes by Light-Induced Cross-Linking of Diacetylene-Based Helical Polymers
Kaho Maeda, Liu Hong, Taishi Nishihara, Yusuke Nakanishi, Yuhei Miyauchi, Ryo Kitaura, Naoki Ousaka, Eiji Yashima, Hideto Ito, Kenichiro Itami
J. Am. Chem. Soc. 2016, 138, 11001–11008. DOI: 10.1021/jacs.6b05582 【detail】【press release (JP)】[press release(EN)]
Selected as the cover art in J. Am. Chem. Soc. 2016, vol.138, issue 38
Highlighted in JACS SPOTLIGHTS (J. Am. Chem. Soc. 2016, 138, 10717. DOI: 10.1021/jacs.6b08657)
Most Read Article Article (Total 2343 views: accessed in 5th, Sep., 2016)
Highlighted in ChemStation Spotlight Research
Highlighted in News Paper: 日経産業新聞20160809、中日新聞20160901, 科学新聞20160906
Other highlights
[Web News in Japanese]: マイナビニュース、gunosy 、excitedニュース、J-Net21 、livedoor 、E-start注目記事、日経テクノロジーオンライン、EE Times Japan 、Yahoo ニュース、Busicom Post 、fabcross for エンジニア、Security Online News 、2channel News Navigator 、はてなブックマーク、ジョルダンニュース !、ニコニコニュース、gooニュース、NTTドコモ、Mapion、Infoseek、Biglobeニュース、日経プレスリリース、
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(236) Thiophene-fused π-Systems from Diarylacetylenes and Elemental Sulfur
Lingkui Meng, Takao Fujikawa, Motonobu Kuwayama, Yasutomo Segawa, Kenichiro Itami
J. Am. Chem. Soc. 2016, 138, 10351-10355. DOI: 10.1021/jacs.6b06486 【detail】【press release (JP)】【press release (EN)】

(235) C-H Activation Enables Rapid Structure-Activity Relationship Study of Arylcyclopropyl amines for Potent and Selective LSD1 Inhibitors
Shin Miyamura, Misaho Araki, Yosuke Ota, Yukihiro Itoh, Shusuke Yasuda, Mitsuharu Masuda, Tomoyuki Taniguchi, Yoshihiro Sowa, Toshiyuki Sakai, Takayoshi Suzuki, Kenichiro Itami, Junichiro Yamaguchi
Org. Biomol. Chem. 2016, 14, 8576-8585. DOI: 10.1039/C6OB01483F【detail】

(234) Cyanation of Phenol Derivatives with Aminoacetonitriles by Nickel Catalysis
Ryosuke Takise, Kenichiro Itami, Junichiro Yamaguchi
Org. Lett. 2016, 18, 4428-4431. DOI: 10.1021/acs.orglett.6b02265【detail】

(233) Corannulene–Helicene Hybrids: Chiral π-Systems Comprising Both Bowl and Helical Motifs
Takao Fujikawa, Dorin V. Preda, Yasutomo Segawa, Kenichiro Itami, Lawrence T. Scott
Org. Lett. 2016, 18, 3992-3995. DOI: 10.1021/acs.orglett.6b01801 【detail】

(232) High-throughput Assay for Quantification of Aminoglycoside–Ribosome Interaction
Shun Yamashita, Dominik Bergmann, Ayato Sato, Mika Nomoto, Yasuomi Tada, Hans-Ulrich Humpf, Kenichiro Itami, Shinya Hagihara
Chem. Lett. 2016, 45, 1048-1050. DOI: 10.1246/cl.160508【detail】

(231) Regiodivergent Cross-Dehydrogenative Coupling of Pyridines and Benzoxazoles: Discovery of Organic Halides as Regio-Switching Oxidants
Shuya Yamada, Kei Murakami, Kenichiro Itami
Org. Lett. 2016, 18, 2415–2418. doi: 10.1021/acs.orglett.6b00932 【detail】

(230) Chemical Synthesis of Cycloparaphenylenes
Yasutomo Segawa, Akiko Yagi, Kenichiro Itami
Chemistry of Carbon Nanostructures, Eds. K. Müllen, X. Feng, Chapter #, De Gruyter (2016).

(229) Helically Twisted Tetracene: Synthesis, Crystal Structure, and Photophysical Properties of Hexabenzo[a,c,fg,j,l,op]tetracene
Yuuta Yano, Hideto Ito, Yasutomo Segawa, Kenichiro Itami
Synlett 2016, 27, 2081-2084. DOI: 10.1055/s-0035-1561455【detail】

(228) Molecules that Control Witchweed Striga
Shinya Hagihara, Masahiko Yoshimura, Yuichiro Tsuchiya, Toshinori Kinoshita, Kenichiro Itami
Kagaku 2016, 71, 35-39.

(227) Cycloparaphenylene as a molecular porous carbon solid with uniform pores exhibiting adsorption-induced softness
Hirotoshi Sakamoto, Toshihiko Fujimori, Xiaolin Li, Katsumi Kaneko, Kai Kan, Noriaki Ozaki, Yuh Hijikata, Stephan Irle, Kenichiro Itami
Chem. Sci. 2016, 7, 4204-4210. doi: 10.1039/C6SC00092D 【detail】

(226) A Theoretical Study on the Strain Energy of Carbon Nanobelts
Yasutomo Segawa, Akiko Yagi, Hideto Ito, Kenichiro Itami
Org. Lett. 2016, 18, 1430–1433. doi: 10.1021/acs.orglett.6b00365 【detail】

(225) Synthesis and Structural Features of Quadruple Helicenes: Highly Distorted π-Systems Enabled by Accumulation of Helical Repulsions
Takao Fujikawa, Yasutomo Segawa, Kenichiro Itami
J. Am. Chem. Soc. 2016, 138, 3587. DOI: 10.1021/jacs.6b01303 【detail】
Highlighted in Chemistry World

(224) The AMOR Arabinogalactan Sugar Chain Induces Pollen-Tube Competency to Respond to Ovular Guidance
Akane G. Mizukami, Rie Inatsugi, Jiao Jiao, Toshihisa Kotake, Keiko Kuwata, Kento Ootani, Satohiro Okuda, Subramanian Sankaranarayanan, Yoshikatsu Sato, Daisuke Maruyama, Hiroaki Iwai, Estelle Gare ́ naux, Chihiro Sato, Ken Kitajima, Yoichi Tsumuraya, Hitoshi Mori, Junichiro Yamaguchi, Kenichiro Itami, Narie Sasaki, Tetsuya Higashiyama
Current Biology 2016, 26, 1091. DOI: 10.1016/j.cub.2016.02.040 【detail】

(223) Palladium-catalyzed C–H Arylation of Pyridines with Aryl Triflates
Jiao Jiao, Kei Murakami, Kenichiro Itami
Chem. Lett. 2016, 45, 529-531. DOI: 10.1246/cl.160133

(222) Synthesis of Triarylpyridines in Thiopeptide Antibiotics Using a C-H Arylation/Ring Transformation Strategy
Kazuma Amaike, Kenichiro Itami, Junichiro Yamaguchi
Chem. Eur. J. 2016, 22, 4384-4388. DOI: 10.1002/chem.201600351【detail】

(221) Structurally uniform and atomically precise carbon nanostructures
Yasutomo Segawa, Hideto Ito, Kenichiro Itami
Nature Rev. Mater. 2016, 1, 15002. DOI: 10.1038/natrevmats.2015.2 【detail】

(220) Design and Synthesis of Carbon Nanotube Segments
Yasutomo Segawa, Akiko Yagi, Katsuma Matsui, Kenichiro Itami
Angew. Chem. Int. Ed. 2016, 55, 5136-5158. DOI: 10.1002/anie.201508384【detail】

(219) Microwave-assisted regioselective direct C–H arylation of thiazole derivatives leading to increased σ1 receptor affinity
Artur Kokornaczyk, Dirk Schepmann, Junichiro Yamaguchi, Kenichiro Itami, Bernhard Wünsch
Med. Chem. Commun. 2016, 7, 327. DOI:10.1039/C5MD00526D【detail】

(218) Catalytic Methods for Aromatic C–H Amination: An Ideal Strategy for Nitrogen-Based Functional Molecules
Jiao Jiao, Kei Murakami, Kenichiro Itami
ACS Catal. 2016, 6, 610-633. DOI: 10.1021/acscatal.5b02417 【detail】

(217) Development and Elucidation of the Ni-Catalyzed Direct Coupling Reaction
Junichiro Yamaguchi, Kei Muto, Kenichiro Itami
Chemical Times (Japanese account) 2016, 2–7. [Link]

(216) Synthesis of Open-Shell Ladder π-Systems by Catalytic C–H Annulation of Diarylacetylenes
Takehisa Maekawa, Hiroshi Ueno, Yasutomo Segawa, Michael M. Haley, Kenichiro Itami
Chem. Sci. 2016, 7, 650-654. DOI: 10.1039/C5SC03391H【detail】

(215) Synthesis of Natural Products and Pharmaceuticals via Catalytic C–H Functionalization
Junichiro Yamaguchi, Kazuma Amaike, Kenichiro Itami
“Transition Metal-Catalyzed Heterocycle Synthesis via C-H Activation” 2016, Wiley-VCH [Link]

(214) Pyridylidene ligand facilitates gold-catalyzed oxidative C–H arylation of heterocycles
Kazuhiro Hata, Hideto Ito, Yasutomo Segawa, Kenichiro Itami
Beilstein J. Org. Chem. 2015, 11, 2737–2746. DOI: 10.3762/bjoc.11.295 【detail】

(213) Concise Synthesis and Facile Nanotube Assembly of a Symmetrically Multi-Functionalized Cycloparaphenylenes
Yuta Miyauchi, Kohei Johmoto, Nobuhiro Yasuda, Hidehiro Uekusa, Shintaro Fujii, Manabu Kiguchi, Hideto Ito, Kenichiro Itami, Ken Tanaka
Chem. Eur. J. 2015, 21, 18900-18904.
Selected as Inside Cover of the journal.

(212) Making Dimethylamino a Transformable Directing Group by Nickel-Catalyzed C-N Borylation
Hua Zhang, Shinya Hagihara, Kenichiro Itami
Chem. Eur. J. 2015, 21, 16796-16800.

(211) C-H Arylation and Alkenylation of Imidazoles by Nickel Catalysis: Solvent-accelerated Imidazole C-H Activation
Kei Muto, Taito Hatakeyama, Junichiro Yamaguchi, Kenichiro Itami
Chem. Sci. 2015, 6, 6792-6798. DOI: 10.1039/C5SC02942B 【detail】

(210) Changing Biological Clock Rhythm by Catalysts: Discovery of New Molecules by Interdisciplinary Research
Kenichiro Itami, Takashi Yoshimura
Kagaku 2015, 70, 18-22.

(209) Probing strigolactone receptors in Striga hermonthica with fluorescence
Yuichiro Tsuchiya, Masahiko Yoshimura, Yoshikatsu Sato, Keiko Kuwata, Shigeo Toh, Duncan Holbrook-Smith, Hua Zhang, Peter McCourt, Kenichiro Itami, Toshinori Kinoshita, Shinya Hagihara
Science 2015, 349, 864. DOI: 10.1126/science.aab3831 【detail】

(208) Synthesis, Properties, and Packing Structures of Corannulene-Based π-Systems Containing Heptagons
Kenta Kato, Yasutomo Segawa, Lawrence T. Scott, Kenichiro Itami
Chem. Asian J. 2015, 10, 1635-1639. DOI: 10.1002/asia.201500560【detail】

(207) Curved Oligophenylenes as Donors in Shape-Persistent Donor–Acceptor Macrocycles with Solvatofluorochromic Properties
Takuya Kuwabara, Jun Orii, Yasutomo Segawa, Kenichiro Itami
Angew. Chem. Int. Ed. 2015, 54, 9646–9649. DOI: 10.1002/anie.201503397【detail】

(206) Porous frameworks constructed by non-covalent linking of substitution-inert metal complexes
Takahiro Itoh, Mio Kondo, Hirotoshi Sakamoto, Kaori Wakabayashi, Mari Kanaike, Kenichiro Itami, Shigeyuki Masaoka
Dalton Trans. 2015, 44, 15334-15342.

(205) Decarbonylative organoboron cross-coupling of esters by nickel catalysis
Kei Muto, Junichiro Yamaguchi, Djamaladdin G. Musaev, Kenichiro Itami
Nature Commun. 2015, 6, 7508. DOI: 10.1038/ncomms8508【detail】

(204) Synthesis, Structures and Properties of π-Extended Double Helicene: A Combination of Planar and Nonplanar π-Systems
Takao Fujikawa, Yasutomo Segawa, Kenichiro Itami
J. Am. Chem. Soc. 2015, 137, 7763-7768. DOI: 10.1021/jacs.5b03118 【detail】

(203) C-H Activation Generates Period-Shortening Molecules That Target Cryptochrome in the Mammalian Circadian Clock
Tsuyoshi Oshima, Iori Yamanaka, Anupriya Kumar, Junichiro Yamaguchi, Taeko Nishiwaki-Ohkawa, Kei Muto, Rika Kawamura, Tsuyoshi Hirota, Kazuhiro Yagita, Stephan Irle, Steve A. Kay, Takashi Yoshimura, Kenichiro Itami
Angew. Chem. Int. Ed. 2015, 54, 7193–7197. DOI: 10.1002/anie.201502942 【detail】
Highlighted in Newspaper (Chunichi Shimbun)

(202) para-C−H Borylation of Benzene Derivatives by a Bulky Iridium Catalyst
Yutaro Saito, Yasutomo Segawa, Kenichiro Itami
J. Am. Chem. Soc. 2015, 137, 5193–5198. DOI: 10.1021/jacs.5b02052 【detail】
Highlighted in Newspaper (Kagaku Shimbun)

(201) Aromatic C–H Borylation by Nickel Catalysis
Hua Zhang, Shinya Hagihara, Kenichiro Itami
Chem. Lett. 2015, 44, 779-781. DOI: 10.1246/cl.150154

(200) Palladium-free Synthesis of [10]Cycloparaphenylene
Yasutomo Segawa, Takuya Kuwabara, Katsuma Matsui, Satoru Kawai, Kenichiro Itami
Tetrahedron 2015, 71, 4500–4503. DOI: 10.1016/j.tet.2015.02.066

(199) Cycloparaphenylene-Based Ionic Donor–Acceptor Supramolecule: Isolation and Characterization of Li+@C60⊂[10]CPP
Hiroshi Ueno, Taishi Nishihara, Yasutomo Segawa, Kenichiro Itami
Angew. Chem. Int. Ed. 2015, 54, 3707-3711. DOI: 10.1002/anie.201500544 【detail】
Selected as the back cover picture

(198) One-shot K-region-selective Annulative π-Extension for Nanographene Synthesis and Functionalization
Kyohei Ozaki, Katsuaki Kawasumi, Mari Shibata, Hideto Ito, Kenichiro Itami
Nature Commun. 2015, 6:6251. DOI: 10.1038/ncomms7251.【detail】
Highlighted in News Papers (Kagaku Shinbun, Chunichi Shinbun, Nikkan Kogyo Shimbun, Zaikeishinbun)
Highlighted in Science Portal, Scicasts, Phys Org, AZO NANO, nano werk, Science Daily, Asia Research News, Eurek Alert.

(197) Catalytic C–H Imidation of Aromatic Cores of Functional Molecules: Ligand-Accelerated Cu Catalysis and Application to Materials- and Biology-Oriented Aromatics
Takahiro Kawakami, Kei Murakami, Kenichiro Itami
J. Am. Chem. Soc. 2015, 137, 2460–2463. DOI: 10.1021/ja5130012. 【detail】
Most Read Articles in February 2015

(196) Synthesis and characterization of hexaarylbenzenes with five or six different substituents enabled by programmed synthesis
Shin Suzuki, Yasutomo Segawa, Kenichiro Itami, Junichiro Yamaguchi
Nature Chem. 2015, 7, 227-233. DOI:10.1038/nchem.2174 【detail】

(195) η6-Cycloparaphenylene Transition Metal Complexes: Synthesis, Structure, Photophysical Properties, and Application to the Selective Monofunctionalization of Cycloparaphenylenes
Natsumi Kubota, Yasutomo Segawa, Kenichiro Itami
J. Am. Chem. Soc. 2015, 137, 1356-1361. DOI: 10.1021/ja512271p 【detail】

(194) Concise Syntheses of Dictyodendrins A and F by a Sequential C–H Functionalization Strategy
Atsushi D. Yamaguchi, Kathryn M. Chepiga, Junichiro Yamaguchi, Kenichiro Itami, Huw M. L. Davies,
J. Am. Chem. Soc. 2015, 137, 644-647. DOI: 10.1021/ja512059d 【detail】

(193) Thiophene-Based, Radial π-Conjugation: Synthesis, Structure, and Photophysical Properties of Cyclo-1,4-phenylene-2′,5′-thienylenes
Hideto Ito, Yukari Mitamura, Yasutomo Segawa, Kenichiro Itami
Angew. Chem. Int. Ed. 2015, 54, 159-163. DOI: 10.1002/anie.201409389【detail】
Selected as a inside cover picture in issue 1, 2015.
Highlighted in Synfacts 2015, 11,141.

(192) Synthesis, binding affinity and structure–activity relationships of novel, selective and dual targeting CCR2 and CCR5 receptor antagonists
Anna Junker, Artur K. Kokornaczyk, Annelien J. M. Zweemer, Bastian Frehland, Dirk Schepmann, Junichiro Yamaguchi, Kenichiro Itami, Andreas Faust, Sven Hermann, Stefan Wagner, Michael Schäfers, Michael Koch, Christina Weiss, Laura H. Heitman, Klaus Kopkai, Bernhard Wünsch
Org. Biomol. Chem. 2015, 13, 2407-2422. DOI: 10.1039/C4OB02397H

(191) Ni-Catalyzed α-Arylation of Esters and Amides with Phenol Derivatives
Eva Koch, Ryosuke Takise, Armido Studer, Junichiro Yamaguchi, Kenichiro Itami
Chem. Commun. 2015, 51, 855. DOI: 10.1039/C4CC08426H　【detail】

(190) Stereodivergent Synthesis of Arylcyclopropylamines by Sequential C–H Borylation and Suzuki–Miyaura Coupling
Shin Miyamura, Misaho Araki, Takayoshi Suzuki, Junichiro Yamaguchi, Kenichiro Itami
Angew. Chem. Int. Ed. 2015, 54, 846-851. DOI: 10.1002/anie.201409186

(189) Synthesis of Extended π-Systems through C–H Activation
Yasutomo Segawa, Takehisa Maekawa, Kenichiro Itami
Angew. Chem. Int. Ed. 2015, 54, 66-81. DOI: 10.1002/anie.201403729 【detail】

(188) All-benzene Carbon Nanocages: Size-selective Synthesis, Photophysical Properties, and Crystal Structure
Katsuma Matsui, Yasutomo Segawa, Kenichiro Itami
J. Am. Chem. Soc. 2014, 136, 16452-16458. DOI: 10.1021/ja509880v 【detail】

(187) Key Mechanistic Features of Ni-catalyzed C–H/C–O Biaryl Coupling of Azoles and Naphthalen-2-yl Pivalates
Huiying Xu, Kei Muto, Junichiro Yamaguchi, Cunyuan Zhao, Djamaladdin G Musaev, Kenichiro Itami
J. Am. Chem. Soc. 2014, 136, 14834. DOI: 10.1021/ja5071174

(186) β-Selective C–H Arylation of Pyrroles Leading to Concise Syntheses of Lamellarins C and I
Kirika Ueda, Kazuma Amaike, Richard M. Maceiczyk, Kenichiro Itami, Junichiro Yamaguchi
J. Am. Chem. Soc. 2014, 136, 13226. DOI: 10.1021/ja508449y 【detail】

(185) Branch-Selective Allylic C–H Carboxylation of Terminal Alkenes by Pd/sox Catalyst
Hiroki Kondo, Feng Yu, Junichiro Yamaguchi, Guosheng Liu, Kenichiro Itami
Org. Lett. 2014, 16, 4212. DOI: 10.1021/ol5019135 【detail】

(184) Nickel-Catalyzed α-Arylation of Ketones with Phenol Derivatives
Ryosuke Takise, Kei Muto, Junichiro Yamaguchi, Kenichiro Itami
Angew. Chem. Int. Ed. 2014, 53, 6791. DOI: 10.1002/anie.201403823
Highlighted in Newspapers (Chemical Daily News, Kagaku Shinbun), Chemistry Views, Chemistry Processing

(183) 2,4- and 2,5-Disubstituted Arylthiazoles: Rapid Synthesis by C–H Coupling and Biological Evaluation
Lilia Lohrey, Takahiro N. Uehara, Satoshi Tani, Junichiro Yamaguchi, Hans-Ulrich Humpf, Kenichiro Itami
Eur. J. Org. Chem. 2014, 3387. DOI: 10.1002/ejoc.201402129 【detail】

(182) Synthesis and Dimerization of Chloro[10]cycloparaphenylene: A Directly Connected Cycloparaphenylene Dimer
Yuuki Ishii, Sanae Matsuura, Yasutomo Segawa, Kenichiro Itami
Org. Lett. 2014, 16, 2174. DOI: 10.1021/ol500643c 【detail】

(181) Excitation Recombination Dynamics in Nanoring Cycloparaphenylenes
Taishi Nishihara, Yasutomo Segawa, Kenichiro Itami, Yoshihiko Kanemitsu
Chem. Sci. 2014, 5, 2293. DOI: 10.1039/c3sc53462f 【detail】

(180) Manganese-Catalyzed Intermolecular C–H/C–H Coupling of Carbonyls and Heteroarenes
Keika Hattori, Asraa Ziadi, Kenichiro Itami, Junichiro Yamaguchi
Chem. Commun. 2014, 50, 4105. DOI:10.1039/C4CC01376J 【detail】
Most Read Article (March, 2014)

(179) Late-Stage C–H Coupling Enables Rapid Identification of HDAC Inhibitors: Synthesis and Evaluation of NCH-31 Analogues
Hiromi Sekizawa, Kazuma Amaike, Yukihiro Itoh, Takayoshi Suzuki, Kenichiro Itami, Junichiro Yamaguchi
ACS Med. Chem. Lett. 2014, 5, 582. DOI: 10.1021/ml500024s 【detail】
Most Read Article (March, 2014)

(178) Size-Selective Complexation and Extraction of Endohedral Metallofullerenes with Cycloparaphenylene
Yusuke Nakanishi, Haruka Omachi, Sanae Matsuura, Yasumitsu Miyata, Ryo Kitaura, Yasutomo Segawa, Kenichiro Itami, Hisanori Shinohara
Angew. Chem. Int. Ed. 2014, 53, 3102-3106. DOI: 10.1002/anie.201311268 【detail】

(177) Cross-Dehydrogenative-Coupling Reactions without Metals
Hideto Ito, Kirika Ueda, Kenichiro Itami
From C-H to C-C Bonds: Cross-Dehydrogenative-Coupling (Eds: Chao-Jun Li, DOI: 10.1039/9781782620082), Chapter 8, Royal Society of Chemistry, 2015, 153–196. DOI: 10.1039/9781782620082-00153.

(176) Tris(1,1,1,3,3,3-hexafluoro-2-propyl)phosphite
Kirika Ueda, Kenichiro Itami
Electronic Encyclopedia of Reagents for Organic Synthesis, Wiley, online.

(175) Synthesis and Properties of Cycloparaphenylene-2,7-pyrenylene: A Pyrene-Containing Carbon Nanoring
Akiko Yagi, Gandikota Venkataramana, Yasutomo Segawa, Kenichiro Itami
Chem. Commun. 2014, 50, 957-959. doi: 10.1039/C3CC48198K 【detail】

(174) Selective Synthesis of [7]- and [8]Cycloparaphenylenes
Friederike Sibbel, Katsuma Matsui, Yasutomo Segawa, Armido Studer, Kenichiro Itami
Chem. Commun. 2014, 50, 954-956. doi: 10.1039/C3CC48683D 【detail】

(173) Synthesis of Dihydrobenzo[b]furans by Diastereoselective Acyloxyarylation
Kazuhiro Hata, Zhiheng He, Constantin Gabriel Daniliuc, Kenichiro Itami, Armido Studer
Chem. Commun. 2014, 50, 463-465. DOI: 10.1039/C3CC47350C 【detail】

(172) Diverse Modification of the 4-Methylphenyl Moiety of TAK-779 by Late-Stage Suzuki-Miyaura Cross-Coupling
Anna Junker, Dirk Schepmann, Junichiro Yamaguchi, Kenichiro Itami, Andreas Faust, Klaus Kopka, Stefan Wagner, Bernhard Wünsch
Org. Biomol. Chem. 2014, 12, 177-186. DOI: 10.1039/C3OB41873A

(171) Programmed Synthesis of Arylthiazoles through Sequential C-H Couplings
Satoshi Tani, Takahiro N. Uehara, Junichiro Yamaguchi, Kenichiro Itami
Chem. Sci. 2014, 5, 123-125. DOI: 10.1039/C3SC52199K 【detail】
Most Read Article (October, 2013), Higlighted in Synfacts

(170) Isolation, Structure, and Reactivity of an Arylnickel(II) Pivalate Complex in Catalytic C-H/C-O Biaryl Coupling
Kei Muto, Junichiro Yamaguchi, Aiwen Lei, Kenichiro Itami
J. Am. Chem. Soc. 2013, 135, 16384–16387. DOI: 10.1021/ja409803x【detail】

(169) Palladium-Catalyzed C–H and C–N Arylation of Aminothiazoles with Arylboronic Acids
Takahiro N. Uehara, Junichiro Yamaguchi, Kenichiro Itami
Asian J. Org. Chem. 2013, 2, 938-942. DOI: 10.1002/ajoc.201300172 【detail】
Most Read Article (November, 2013, Highlighted in ChemistryViews and Wiley science Cafe)
(Dedicated to Professor Teruaki Mukaiyama on the occasion of the 40th anniversary of the Mukaiyama aldol reaction)
Highlighted in Chemistry Views

(168) C–H Alkenylation of Azoles with Enols and Esters by Nickel Catalysis
Lingkui Meng, Yuko Kamada, Kei Muto, Junichiro Yamaguchi, Kenichiro Itami
Angew. Chem. Int. Ed. 2013, 52, 10048–10051. DOI: 10.1002/anie.201304492 【detail】
Highlighted in Newspapers (Chunichi Shinbun, Mynavi News, and Yahoo News).

(167) A grossly warped nanographene and the consequences of multiple odd-membered-ring defects
Katsuaki Kawasumi, Qianyan Zhang, Yasutomo Segawa, Lawrence T. Scott, Kenichiro Itami
Nature Chem. 2013, 5, 739-744. doi: 10.1038/nchem.1704 【detail】
Selected as the cover image of Nature Chemistry. Ranked as the 4th high-scored paper among all Nature Chemistry papers.
Highlighted in Newspapers (Yomiuri Shimbun, Chunichi Shimbun, Nikkan Kogyo Shimbun, Tokyo Shimbun, MyNavi News, Kyodo-Tsushin, Kagaku Shimbun).
Highlighted in Chemistry World
Highlighted in C&EN
Featured in Nature Chem (News and Views).

(166) One-shot Indole-to-Carbazole π-Extension by Pd-Cu-Ag Trimetallic System
Kyohei Ozaki, Hua Zhang, Hideto Ito, Aiwen Lei, Kenichiro Itami
Chem. Sci. 2013, 4, 3416–3420, DOI: 10.1039/C3SC51447A 【detail】
Most Read Articles in June and July in 2013
Selected as “HOT Chem Sci articles for June” in 2013
Selected as Back Cover in issue 9, 2013
Highlighted in Synfacts
Selected as “Top 25 most-read Chemical Science articles in 2013”

(165) Aromatic C–H Coupling with Hindered Arylboronic Acids by Pd/Fe Dual Catalysts
Kazuya Yamaguchi, Hiroki Kondo, Junichiro Yamaguchi, Kenichiro Itami
Chem. Sci. 2013, 4, 3753-3757. DOI: 10.1039/C3SC51206A 【detail】

(164) Initiation of carbon nanotube growth by well-defined carbon nanorings
Haruka Omachi, Takuya Nakayama, Eri Takahashi, Yasutomo Segawa, Kenichiro Itami
Nature Chem. 2013, 5, 572–576. DOI: 10.1038/NCHEM.1655 【detail】
Highlighted in Newspapers (Yomiuri, Chunichi, Tokyo Shinbun, Kagaku Shinbun, Nikkan Kogyo Shinbun, Nanotech Japan)
Highlighted in Chemistry World

(163) Nickel-Catalyzed Direct Coupling of Heteroarenes
Junichiro Yamaguchi, Kei Muto, Kazuma Amaike, Takuya Yamamoto, Kenichiro Itami
J. Synth. Org. Chem. Jpn. 2013, 71, 576-587.

(162) Synthesis of Thiophene-Based TAK-779 Analogues by C–H Arylation
Anna Junker, Junichiro Yamaguchi, Kenichiro Itami, Bernhard Wünsch
J. Org. Chem. 2013, 78, 5579–5586. DOI: 10.1021/jo400692p 【detail】

(161) New Cross-coupling Reactions through Nickel Catalysis
Junichiro Yamaguchi, Kazuma Amaike, Kei Muto, Kenichiro Itami
Catalysis 2013, 624-645.

(160) Pyridine-Based Dicarbene Ligand: Synthesis and Structure of Bis-2-pyridylidene Palladium Complex
Tetsushi Yoshidomi, Yasutomo Segawa, Kenichiro Itami
Chem. Commun. 2013, 49, 5648-5650. DOI: 10.1039/C3CC42655F 【detail】

(159) Decarbonylative C–H Biaryl Coupling
Junichiro Yamaguchi, Kenichiro Itami
Kagaku 2013, 35-39.

(158) C-H Activation Route to Dibenzo[a,e]pentalenes: Annulation of Arylacetylenes Promoted by PdCl2/AgOTf/o-chloranil
Takehisa Maekawa, Yasutomo Segawa, Kenichiro Itami
Chem. Sci. 2013, 4, 2369-2373. DOI: 10.1039/C3SC50585E 【detail】
Highlighted in Synfacts

(157) Improvement of σ1 receptor affinity by late-stage C–H bond arylation of spiro cyclic lactones
Christina Meyer, Benedikt Neue, Dirk Schepmann, Shuichi Yanagisawa, Junichiro Yamaguchi, Ernst-Ulrich Würthwein, Kenichiro Itami, Bernhard Wünsch
Bioorg. Med. Chem. 2013, 21, 1844. DOI: 10.1016/j.bmc.2013.01.038

(156) Palladium-catalyzed direct phenylation of perylene: Structural and optical properties of 3,4,9-triphenylperylene and 3,4,9,10-tetraphenylperylene
Katsuaki Kawasumi, Kenji Mochida, Yasutomo Segawa, Kenichiro Itami
Tetrahedron 2013, 69, 4371. DOI: 10.1016/j.tet.2013.01.037 【detail】

(155) Origin of the Size-Dependent Fluorescence Blueshift in [n]Cycloparaphenylenes
Cristopher Camacho, Thomas A. Niehaus, Kenichiro Itami, Stephan Irle
Chem. Sci. 2013, 4, 187-195. DOI: 10.1039/C2SC20878D 【detail】

(154) Excited States in Cycloparaphenylenes: Dependence of Optical Properties on Ring Length
Taishi Nishihara, Yasutomo Segawa, Kenichiro Itami, Yoshihiko Kanemitsu
J. Phys. Chem. Lett. 2012, 3, 1325-3128. DOI: 10.1021/jz3014826 【detail】

(153) Palladium-Catalyzed C–H Activation Taken to the Limit. Flattening an Aromatic Bowl by Total Arylation
Qianyan Zhang, Katsuaki Kawasumi, Yasutomo Segawa, Kenichiro Itami, Lawrence T. Scott
J. Am. Chem. Soc. 2012, 134, 15664–15667. DOI: 10.1021/ja306992k 【detail】
Highlighted in Computational Chemistry Highlights
Most Read Article in September 2012

(152) Palladium-catalyzed tetraallylation of C60 with allyl chloride and allylstannane: Mechanism, regioselectivity, and enantioselectivity
Masakazu Nambo, Atsushi Wakamiya, Kenichiro Itami
Chem. Sci. 2012, 3, 3474-3481. DOI: 10.1039/C2SC21126B 【detail】

(151) Synthesis and Properties of All-Benzene Carbon Nanocages: A Junction Unit of Branched Carbon Nanotubes
Katsuma Matsui, Yasutomo Segawa, Tomotaka Namikawa, Kenji Kamada, Kenichiro Itami
Chem. Sci. 2013, 4, 84-88. DOI: 10.1039/C2SC21322B 【detail】
Highlighted in Newspapers (Yomiuri Shinbun, Chunichi Shinbun, JIJI Press, Yahoo! News, The Chemical Daily, Tokyo Shinbun, Kagaku Shinbun)
Highlighted in Chemistry World, C&EN, Newton, SYNFACTS
Most Read Articles in August and September 2012
Selected as Inside Back Cover

(150) Pd-catalyzed direct C-H bond functionalization of spirocyclic sigma-1 ligands: generation of a pharmacophore model and analysis of reverse binding mode by docking into a 3D homology model of the sigma-1 receptor
Christina Meyer, Dirk Schepmann, Shuichi Yanagisawa, Junichiro Yamaguchi, Valentina Dal Col, Erik Laurini, Kenichiro Itami, Sabrina Pricl, Bernhard Wünsch
J. Med. Chem. 2012, 55, 8047. DOI: 10.1021/jm300894h 【detail】

(149) Late-Stage C-H Bond Arylation of Spirocyclic s1 Ligands for Analysis of Complementary s1 Receptor Surface
Christina Meyer, Dirk Schepmann, Shuichi Yanagisawa, Junichiro Yamaguchi, Bernhard Wünsch, Kenichiro Itami
Eur. J. Org. Chem. 2012, 5972–5979. DOI: 10.1002/ejoc.201200837 【detail】

(148) Recent Progress in Nickel-Catalyzed Biaryl Coupling
Junichiro Yamaguchi, Kei Muto, Kenichiro Itami
Eur. J. Org. Chem. 2013, 19-30. DOI: 10.1002/ejoc.201200914 【detail】

(147) Synthesis of Bioactive Compounds through C-H Bond Functionalization
Junichiro Yamaguchi, Kenichiro Itami
Fine Chemicals 2012, 41, 38.

(146) Chemical Synthesis of Nanographenes
Katsuaki Kawasumi, Kenichiro Itami
Function and Applications of Graphenes 2 2012, 102-110.

(145) Direct C-H Arylation of Polycyclic Aromatic Hydrocarbons toward Bottom-up Synthesis of Graphene
Yasutomo Segawa, Kenichiro Itami
Catalysts and Catalysis 2012, 54, 409-413. 【detail】

(144) Biaryl Synthesis through Metal-Catalyzed C-H Arylation
Junichiro Yamaguchi, Kenichiro Itami
Metal Catalyzed Cross-Coupling Reactions and More; Wiley-VCH, 2014.

(143) C-H Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals
Junichiro Yamaguchi, Atsushi D. Yamaguchi, Kenichiro Itami
Angew. Chem. Int. Ed. 2012, 51, 8960–9009. 10.1002/anie.201201666 【detail】
Selected as the Cover of the Issue.
Highlighted in Chemistry Views.

(142) Decarbonylative C–H Coupling of Azoles and Aryl Esters: Unprecedented Nickel Catalysis and Application to the Synthesis of Muscoride A
Kazuma Amaike, Kei Muto, Junichiro Yamaguchi, Kenichiro Itami
J. Am. Chem. Soc. 2012, 134, 13573–13576. DOI: 10.1021/ja306062c　【detail】
Highlighted in Newspapers (Chu-nichi, Asahi, The Chemical Daily, Yahoo!News, Mynavi-News, Nikkan kogyo, Kagaku Shinbun)
Most Read Articles in August 2012

(141) Pd- and Cu-catalyzed C–H Arylation of Indazoles
Keika Hattori, Kazuya Yamaguchi, Junichiro Yamaguchi, Kenichiro Itami
Tetrahedron 2012, 68, 7605-7612. DOI: 10.1016/j.tet.2012.05.091

(140) 1,3,5-Triaryl 2-Pyridylidene: Base-Promoted Generation and Complexation
Kazuhiro Hata, Yasutomo Segawa, Kenichiro Itami
Chem. Commun. 2012, 48, 6642–6644. DOI: 10.1039/C2CC33184E 【detail】

(139) Carbon Nanoring: A Shortest Carbon Nanotube
Yasutomo Segawa, Kenichiro Itami
Expected Materials for the Future, 2012, 12, 10-15. link【detail】

(138) Size-selective synthesis of [9]-[11] and [13]cycloparaphenylenes
Yuuki Ishii, Yusuke Nakanishi, Haruka Omachi, Sanae Matsuura, Katsuma Matsui, Hisanori Shinohara, Yasutomo Segawa, Kenichiro Itami
Chem. Sci. 2012, 3, 2340-2345. DOI: 10.1039/C2SC20343J 【detail】
Highlighted in RSC Chemical Science Blog
Top ten most accessed articles in May 2012

(137) Synthesis of Cycloparaphenylenes and Related Carbon Nanorings: A Step toward the Controlled Synthesis of Carbon Nanotubes
Haruka Omachi, Yasutomo Segawa, Kenichiro Itami
Acc. Chem. Res. 2012, 45, 1378-1389. DOI: 10.1021/ar300055x 【detail】
Most Read Articles in May 2012
Selected as the Cover in the Issue of August 2012

(136) Hindered Biaryls by C-H Coupling: Bisoxazoline-Pd Catalysis Leading to Enantioselective C-H Coupling
Kazuya Yamaguchi, Junichiro Yamaguchi, Armido Studer, Kenichiro Itami
Chem. Sci. 2012, 3, 2165-2169. DOI:10.1039/C2SC20277H【details】
Highlighted in RSC Chemical Science blog
Most Read Articles in March and April 2012

(135) Synthesis and Properties of Cycloparaphenylene-2,5-pyridylidene: A Nitrogen-Containing Carbon Nanoring
Katsuma Matsui, Yasutomo Segawa, Kenichiro Itami
Org. Lett. 2012, 14, 1888-1891. DOI: 10.1021/ol3005112 【details】

(134) Combined Experimental and Theoretical Studies on the Photophysical Properties of Cycloparaphenylenes
Yasutomo Segawa, Aiko Fukazawa, Sanae Matsuura, Haruka Omachi, Shigehiro Yamaguchi, Stephan Irle, Kenichiro Itami
Org. Biomol. Chem. 2012, 10, 5979-5984. DOI: 10.1039/C2OB25199J 【details】

(133) Synthesis and Properties of [9]Cyclo-1,4-naphthylene: A pi-Extended Carbon Nanoring
Akiko Yagi, Yasutomo Segawa, Kenichiro Itami
J. Am. Chem. Soc. 2012, 134, 2962–2965. DOI: 10.1021/ja300001g 【detail】
Most Read Articles (February, 2012)
Highlighted in Computational Organic Chemistry
Highlighted in JACS Image Challenge (JACSß)

(132) Toward Controlled Synthesis of Carbon Nanotubes and Graphene
Kenichiro Itami
Pure Appl. Chem. 2012, 84, 907-916. DOI: 10.1351/PAC-CON-11-11-15s【detail】

(131) Mechanistic Studies on the Pd-catalyzed Direct C-H Arylation of 2-Substituted Thiophene Derivatives with Arylpalladium Bipyridyl Complexes
Marc Steinmetz, Kirika Ueda, Stefan Grimme, Junichiro Yamaguchi, Sylvia Kirchberg, Kenichiro Itami, Armido Studer
Chem. Asian J. 2012, 7, 1256-1260. DOI: 10.1002/asia.201101011 【detail】

(130) The 1,1-Carboboration of Bis(alkynyl)phosphines as a Route to Phosphole Compounds
Juri Möbus, Quentin Bonnin, Kirika Ueda, Roland Fröhlich, Kenichiro Itami, Gerald Kehr, Gerhard Erker
Angew. Chem. Int. Ed. 2012, 51, 1954-1957. DOI: 10.1002/anie.201107398 【details

(129) CPP: A Beautiful Benzene-Based Ring Molecule
Kenichiro Itami
Chemistry & Chemical Industry 2012, 65, 115-116.

(128) Pd(OAc)2/o-Chloranil/M(OTf)n: A Catalyst for the Direct C–H Arylation of Polycyclic Aromatic Hydrocarbons with Boryl-, Silyl-, and Unfunctionalized Arenes
Katsuaki Kawasumi, Kenji Mochida, Tomonori Kajino, Yasutomo Segawa, Kenichiro Itami
Org. Lett. 2012, 14, 418–421. DOI: 10.1021/ol203235w 【details】

(127) Nickel-Catalyzed C−H/C−O Coupling of Azoles with Phenol Derivatives
Kei Muto, Junichiro Yamaguchi, Kenichiro Itami
J. Am. Chem. Soc. 2012, 134, 169-172. DOI: 10.1021/ja210249h 【details】
Highlighted in Newspapers (Yomiuri, Chu-nichi, The Chemical Daily, Yahoo!News, NanotechJapan Nikkan kogyo, Kagaku Shinbun), Most Read Articles (January, 2012), Highlighted as a “SynStory” article in SYNFORM (April 2012), Highlighted in Chemical Engineering (Feb 2012)

(126) Functionalization of a Simple Dithienylethene via Palladium-Catalyzed Regioselective Direct Arylation
Hiroki Kamiya, Shuichi Yanagisawa, Satoru Hiroto, Kenichiro Itami, Hiroshi Shinokubo
Org. Lett. 2011, 13, 6394–6397. DOI: 10.1021/ol2026069 【details】

(125) Synthesis of Dragmacidin D via Direct C-H Couplings
Debashis, Mandal, Atsushi, D. Yamaguchi, Junichiro, Yamaguchi, Kenichiro Itami
J. Am. Chem. Soc. 2011, 133, 19660–19663. DOI: 10.1021/ja209945x 【details】
Most Read Articles (November 2011), Highlighted in Chemistry World

(124) Exploitation of an additional hydrophobic pocket of σ1 receptors: Late-stage diverse modifications of spirocyclic thiophenes by C–H bond functionalization
Christina Meyer, Benedikt Neue, Dirk Schepmann, Shuichi Yanagisawa, Junichiro Yamaguchi, Ernst-Ulrich Würthwein, Kenichiro Itami, Bernhard Wünsch
Org. Biomol. Chem. 2011, 9, 8016. DOI: 10.1039/C1OB06149F 【details】

(123) Molecular Catalysis for Fullerene Functionalization
Kenichiro Itami
Chem. Rec. 2011, 11, 226. DOI:10.1002/tcr.201100022 【details】
Most accessed papers in 10/2011

(122) Synthesis of Bioactive Compounds through C-H Bond Functionalization (Japanese Review)
Junichiro Yamaguchi, Kenichiro Itami
Catalysts & Catalysis 2011, 53, 293. Link 【details】
Top 5 most accessed articles

(121) Direct Arylation of Polycyclic Aromatic Hydrocarbons through Palladium Catalysis
Kenji Mochida, Katsuaki Kawasumi, Yasutomo Segawa, Kenichiro Itami
J. Am .Chem .Soc. 2011, 133, 10716-10719. DOI: 10.1021/ja202975w 【details】
Highlighted in Newspapers (Chunichi, The Chemical Daily, Mainichi Communications, Nikkan Kogyo, Yahoo! News, Goo News, Nanotech Japan, Nikkei Business Daily)
Highlighted in SYNFACTS
Highlighted in Chemistry World

(120) Nickel-Catalyzed C–H Arylation of Azoles with Haloarenes: Scope, Mechanism, and Applications to the Synthesis of Bioactive Molecules
Takuya Yamamoto, Kei Muto, Masato Komiyama, Jerome Canivet, Junichiro Yamaguchi, Kenichiro Itami
Chem. Eur. J. 2011, 17, 10113-10122. DOI: 10.1002/chem.201101091 【details】
Highlighted in SYNFACTS, Most Accessed Article (2/2011-3/2012)

(119) Controlled Alcohol-Carbonyl Interconversion by Nickel Catalysis
Takehisa Maekawa, Hiromi Sekizawa, Kenichiro Itami
Angew. Chem. Int. Ed. 2011, 50, 7022-7026 . DOI: 10.1002/anie.201102092 【details】
Highlighted in Org. Proc. Res. Dev.
Highlighted in SYNFACTS

(118) Oxidative C–H/C–H Coupling of Azine and Indole/Pyrrole Nuclei: Palladium Catalysis and Synthesis of Eudistomin U
Atsushi D. Yamaguchi, Debashis Mandal, Junichiro Yamaguchi, Kenichiro Itami
Chem. Lett. 2011, 40, 555 -557. DOI: 10.1246/cl.2011.555 【details】
Selected as “Editor’s Choice”
Most-accessed Articles
Highlighted in Angew. Chem. Int. Ed.
Highlighted in Synlett

(117) Synthesis and Racemization Process of Chiral Carbon Nanorings: A Step Toward the Chemical Synthesis of Chiral Carbon Nanotubes
Haruka Omachi, Yasutomo Segawa, Kenichiro itami
Org. Lett. 2011, 13, 2480-2483. DOI: 10.1021/ol200730m【details】
Highlighted in Computational Organic Chemistry

(116) Is Total Synthesis of Fullerenes or Carbon Nanotubes Possible?
Kenichiro Itami
Kagaku 2011, 66, 23-27.

(115) Electrophilic Metalation Mechanism or Base-Assisted Proton Abstraction Mechanism
Kenichiro Itami
CSJ Current Review (Bond Activation and Molecular Activation), Kagaku Dojin, 2011.

(114) Multiple Arylation of Aromatic Compounds for Organic Materials
Kenichiro Itami
CSJ Current Review (Bond Activation and Molecular Activation), Kagaku Dojin, 2011.

(113) Palladium/2,2′-bipyridyl/Ag2CO3 catalyst for C-H bond arylation of heteroarenes with haloarenes
Shuichi Yanagisawa, Kenichiro Itami
Tetrahedron 2011, 67, 4425-4430. DOI: 10.1016/j.tet.2011.03.093【details】

(112) [9]Cycloparaphenylene: Nickel-Mediated Synthesis and Crystal Structure
Yasutomo Segawa, Petr Šenel, Sanae Matsuura, Haruka Omachi, Kenichiro Itami
Chem. Lett. 2011, 40, 423–425. DOI: 10.1246/cl.2011.423【details】
Selected as “Editor’s Choice”

(111) Aziridinofullerene: A Versatile Platform for Functionalized Fullerenes
Masakazu Nambo, Yasutomo Segawa, Kenichiro Itami
J. Am. Chem. Soc. 2011, 133, 2402-2405. DOI: 10.1021/ja111213k 【details】
Highlighted in SYNFACTS

(110) Concise Synthesis and Crystal Structure of [12]Cycloparaphenylene
Yasutomo Segawa, Shinpei Miyamoto, Haruka Omachi, Sanae Matsuura, Petr Šenel, Takahiro Sasamori, Norihiro Tokitoh, Kenichiro Itami
Angew. Chem. Int. Ed. 2011, 50, 3244-3248. DOI: 10.1002/anie.201007232 【details】
Highlighted in Science

(109) t-Butoxide-Mediated C-H Bond Arylation of Aromatic Compounds with Haloarenes
Shuichi Yanagisawa, Kenichiro Itami
ChemCatChem 2011, 3, 827-829. DOI: 10.1002/cctc.201000431 【details】

(108) Oxidative Biaryl Coupling of Thiophenes and Thiazoles with Arylboronic Acids through Palladium Catalysis: Otherwise-Difficult C4-Selective C-H Arylation Enabled by Boronic Acids
Sylvia Kirchberg, Satoshi Tani, Kirika Ueda, Junichiro Yamaguchi, Armido Studer, Kenichiro Itami
Angew. Chem. Int. Ed. 2011, 50, 2387-2391, DOI: 10.1002/anie.201007060【details】
Highlighted in SYNFACTS

(107) Selective Introduction of Organic Groups to C60 and C70 Using Organoboron Compounds and Rhodium Catalyst: A New Synthetic Approach to Organo(hydro)fullerenes
Masakazu Nambo, Yasutomo Segawa, Atsushi Wakamiya, Kenichiro Itami
Chem. Asian J. 2011, 6, 590-598. DOI: 10.1002/asia.201000583【details】

(106) A Modular and Size-Selective Synthesis of [n]Cycloparaphenylenes: A Step toward the Selective Synthesis of [n,n] Single-Walled Carbon Nanotubes
Haruka Omachi, Sanae Matsuura, Yasutomo Segawa, Kenichiro Itami
Angew. Chem. Int. Ed. 2010, 49, 10202–10205. DOI: 10.1002/anie.201005734【details】
Selected as “HOT PAPER”
Highlighted in Newspapers (Asahi, Chunichi, Yomiuri, Nikkan Kogyo, The Chemical Daily, NanotechJapan)
Highlighted in Nature
Highlighted in SYNFACTS
Highlighted in 現代化学

(105) Toward Ideal Arene Assembly: Catalytic C–H Bond Arylation of Aromatic Compounds
Kenichiro Itami
J. Synth. Org. Chem. Jpn. 2010, 68, 1132-1141.

(104) A General Catalyst for the β-Selective C-H Bond Arylation of Thiophenes with Iodoarenes
Kirika Ueda, Shuichi Yanagisawa, Junichiro Yamaguchi, Kenichiro Itami
Angew. Chem. Int. Ed. 2010, 49, 8946-8949. DOI: 10.1002/anie.201005082【details】
Highlighted in SYNFACTS

(103) Rhodium-Catalyzed C-H Bond Arylation of Arenes
Jean Bouffard, Kenichiro Itami
Topics in Current Chemistry (Volume: C-H Activation); Springer, 2010, 292, 231-280.

(102) Theoretical Studies on the Structures and Strain Energies of Cycloparaphenylenes
Yasutomo Segawa, Haruka Omachi, Kenichiro Itami
Org. Lett. 2010, 12, 2262-2265. DOI: 10.1021/ol1006168 【details】

(101) Photopatterning of Poly(arylene dienylene) by the Photoacid-Catalyzed Deprotection-Elimination Reaction of a Precursor Polymer
Jean Bouffard, Mitsuru Watanabe, Hiroko Takaba, Kenichiro Itami
Macromolecules 2010, 43, 1425-1429. DOI: 10.1021/ma902442r
Highlighted in SYNFACTS

(100) Regioselective Unsymmetrical Tetraallylation of C60 through Palladium Catalysis
Masakazu Nambo, Atsushi Wakamiya, Shigehiro Yamaguchi, Kenichiro Itami
J. Am. Chem. Soc. 2009, 131, 15112-15113. DOI: 10.1021/ja9071173 【details】
Highlighted in SYNFACTS

(99) Programmed Synthesis of Tetraarylthiophenes through Sequential C-H Arylation
Shuichi Yanagisawa, Kirika Ueda, Hiromi Sekizawa, Kenichiro Itami
J. Am. Chem. Soc. 2009, 131, 14622-14623. DOI: 10.1021/ja906215b【details】
Highlighted in SYNFACTS

(98) A Nickel Catalyst for the Addition of Organoboronate Esters to Ketones and Aldehydes
Jean Bouffard, Kenichiro Itami
Org. Lett. 2009, 11, 4410-4413. DOI:10.1021/ol9017613 【details】
Highlighted in SYNFACTS

(97) Structure-Affinity-Relationship Study of Bicyclic Sigma Receptor Ligands
Ralph Holl, Christian Geiger, Masakazu Nambo, Kenichiro Itami, Dirk Schepmann, Bernhard Wünsch
Cent. Nerv. Syst. Agents Med. Chem. 2009, 9, 220-229.

(96) Fe-Catalyzed Oxidative Coupling of Heteroarenes and Methylamines
Masaki Ohta, Matthias P. Quick, Junichiro Yamaguchi, Bernhard Wünsch, Kenichiro Itami
Chem. Asian J. 2009, 4, 1416-1419. DOI:10.1002/asia.200900157 【details】
Most-Accessed Articles (July/August 2009)

(95) Selective Synthesis of [12]Cycloparaphenylene
Hiroko Takaba, Haruka Omachi, Yosuke Yamamoto, Jean Bouffard, Kenichiro Itami
Angew. Chem. Int. Ed. 2009, 48, 6112-6116. DOI: 10.1002/anie.200902617 【details】
Most-Accessed Articles (July 2009)
Highlighted in Newspapers and Media (Asahi, Chunichi, Yomiuri, Nikkei, Nikkan Kogyo, JIJI, Yahoo News, etc)
Highlighted in Chem-Station (http://www.chem-station.com/blog/2009/07/post-100.html)
Highlighted as a “SynStory” article in SYNFORM (September 2009)
Highlighted in SYNFACTS
Highlighted in Chemistry and Industry
Highlighted in OM News (www.kinka.or.jp/OM/OM%20News/om2010_2_10.pdf)

(94) Arene-Assembling Reactions through C-H Bond Functionalization
Kenichiro Itami
Organometallic News 2009, 50-55.

(93) Iridium Catalysis for C-H Bond Arylation of Heteroarenes with Iodoarenes
Benoit Join, Takuya Yamamoto, Kenichiro Itami
Angew. Chem. Int. Ed. 2009, 48, 3644-3647. DOI: 10.1002/anie.200806358 【details】
Selected as “HOT PAPER”
Most-Accessed Articles (April 2009)
Highlighted in SYNFACTS

(92) Nickel-Catalyzed Biaryl Coupling of Heteroarenes and Aryl Halides/Triflates
Jerome Canivet, Junichiro Yamaguchi, Ikuya Ban, Kenichiro Itami
Org. Lett. 2009, 11, 1733-1736. DOI: 10.1021/ol9001587 【details】
Highlighted in SYNFACTS
Top 20 Most Cited Articles 2009-2011

(91) Palladium-Catalyzed Carbon-Carbon Bond Formation and Cleavage of Organo(hydro)fullerenes
Masakazu Nambo, Kenichiro Itami
Chem. Eur. J. 2009, 15, 4760-4764. DOI: 10.1002/chem.200900022
Selected as COVER PICTURE
Highlighted in SYNFACTS

(90) Palladium(II)-Catalyzed Conjugate Phosphination of Electron-Deficient Acceptors
Verena T. Trepohl, Susumu Mori, Kenichiro Itami, Martin Oestreich
Org. Lett. 2009, 11, 1091-1094. DOI: 10.1021/ol8028466

(89) Arylation of Allylsilanes through Rhodium Catalysis
Haruka Omachi, Kenichiro Itami
Chem. Lett. 2009, 38, 186-187. DOI: 10.1246/cl.2009.186

(88) Coupling of Nitrogen Heteroaromatics and Alkanes without Transition Metal: A New Oxidative Cross-Coupling at C-H/C-H Bonds
Guojun Deng, Kirika Ueda, Shuichi Yanagisawa, Kenichiro Itami, Chao-Jun Li
Chem. Eur. J. 2009, 15, 333-337. DOI: 10.1002/chem.200801893 【details】
Most-Accessed Articles (December 2008)

(87) Synthesis of New Nano Carbon Materials
Masakazu Nambo, Kenichiro Itami
McGraw-Hill Yearbook of Science & Technology 2009, 379-381.

(86) Potassium t-Butoxide Alone Can Promote the Biaryl Coupling of Electron-Deficient Nitrogen Heterocycles and Haloarenes
Shuichi Yanagisawa, Kirika Ueda, Tadashi Taniguchi, Kenichiro Itami
Org. Lett. 2008, 10, 4673-4676. DOI: 10.1021/ol8019764
Highlighted in J. Synth. Org. Chem. Jpn.
Highlighted in Nature Chemistry
Highlighted in Angew. Chem. Int. Ed.

(85) A Bench-Stable Pd Catalyst for the Hydroarylation of Fullerene with Boronic Acids
Susumu Mori, Masakazu Nambo, Liang-Chen Chi, Jean Bouffard, Kenichiro Itami
Org. Lett. 2008, 10, 4609-4612. DOI: 10.1021/ol801936j
Highlighted in SYNFACTS.
Highlighted in J. Synth. Org. Chem. Jpn.

(84) Copper-Mediated C-H Bond Arylation of Arenes with Arylboronic Acids
Ikuya Ban, Tomoko Sudo, Tadashi Taniguchi, Kenichiro Itami
Org. Lett. 2008, 10, 3607-3609. DOI: 10.1021/ol80137170
Highlighted in SYNFACTS.
Highlighted in J. Synth. Org. Chem. Jpn.
Top 20 Most Cited Articles 2008-2010

(83) Chelation-Controlled Mizoroki-Heck Reactions
Kenichiro Itami, Jun-ichi Yoshida
The Mizoroki-Heck Reaction; Wiley-VCH, Chap 4 (2008).

(82) Carbomagnesiation Reactions
Kenichiro Itami, Jun-ichi Yoshida
The Chemistry of Organomagnesium Compounds, Wiley-VCH, Chap 14, 631-680 (2008).

(81) Direct Coupling of Arenes and Iodoarenes Catalyzed by Rhodium Complex with Strongly pi-Accepting Phosphite Ligand
Shuichi Yanagisawa, Tomoko Sudo, Ryoji Noyori, Kenichiro Itami
Tetrahedron 2008, 64, 6073-6081. DOI: 10.1016/j.tet.2008.01.053

(80) Catalytic Direct Functionalization of Olefins, Aromatics, and Fullerenes
Kenichiro Itami
Kobunshi 2008, 57, 134-137.

(79) Rh-Catalyzed Arylation and Alkenylation of C₆₀ Using Organoboron Compounds
Masakazu Nambo, Ryoji Noyori, Kenichiro Itami
J. Am. Chem. Soc. 2007, 129, 8080-8081.
Highlighted in Synfacts.

(78) Generation of Pyridyl Coordinated Organosilicon Cation Pool by Oxidative Si-Si Bond Dissociation
Toshiki Nokami, Ryoji Soma, Yoshimasa Yamamoto, Toshiyuki Kamei, Kenichiro Itami, Jun-ichi Yoshida
Beilstein J. Org. Chem. 2007, 3, 7.

(77) Direct C-H Arylation of (Hetero)arenes with Aryl Iodides via Rhodium Catalysis
Shuichi Yanagisawa, Tomoko Sudo, Ryoji Noyori, Kenichiro Itami
J. Am. Chem. Soc. 2006, 128, 11748-11749.
Highlighted in Science, Synfacts.

(76) Multisubstituted Olefins: Platform Synthesis and Applications to Materials Science and Pharmaceutical Chemistry
Kenichiro Itami, Jun-ichi Yoshida
Bull. Chem. Soc. Jpn. 2006, 79, 811-824.
Award Account.

(75) Platform Synthesis: A Useful Strategy for Rapid and Systematic Generation of Molecular Diversity
Kenichiro Itami, Jun-ichi Yoshida
Chem. Eur. J. 2006, 12, 3966-3974.

(74) Sequential Pd- and Rh-Catalyzed Three-Component Cyclization with Allenylboronate Platform
Keisuke Tonogaki, Kenichiro Itami, Jun-ichi Yoshida
Org. Lett. 2006, 8, 1419-1422.
Highlighted in Synfacts.

(73) Palladium-Catalyzed Convergent Synthesis and Properties of Conjugated Dendrimers Based on Triarylethene Branching
Kenichiro Itami, Keisuke Tonogaki, Toshiki Nokami, Youichi Ohashi, Jun-ichi Yoshida
Angew. Chem. Int. Ed. 2006, 45, 2404-2409.
Highlighted in Synfacts.

(72) Palladium-Catalyzed Cross-Coupling Reactions of (2-Pyridyl)allyldimethylsilanes with Aryl Iodides
Toshiki Nokami, Yutaka Tomida, Toshiyuki Kamei, Kenichiro Itami, Jun-ichi Yoshida
Org. Lett. 2006, 8, 729-731.

(71) Catalytic Four-Component Assembly Based on Allenylboronate Platform: New Access to Privileged Allylic Amine Structures
Keisuke Tonogaki, Kenichiro Itami, Jun-ichi Yoshida
J. Am. Chem. Soc. 2006, 128, 1464-1465.
Highlighted in Synfacts.

(70) 2-Pyridylsilyl Group: A Useful Multifunctional Group in Organic Synthesis
Kenichiro Itami, Jun-ichi Yoshida
Synlett 2006, 157-180.

(69) Copper-Catalyzed Allylation of Carbonyl Derivatives Using Allyl(2-pyridyl)silanes
Toshiyuki Kamei, Kazuyoshi Fujita, Kenichiro Itami, Jun-ichi Yoshida
Org. Lett. 2005, 7, 4725-4728.

(68) Rapid Synthesis of CDP840 with 2-Pyrimidyl Vinyl Sulfide as a Platform
Nobuhiro Muraoka, Masahiro Mineno, Kenichiro Itami, Jun-ichi Yoshida
J. Org. Chem. 2005, 70, 6933-6936.

(67) Versatile Synthesis of 1,1-Diaryl-1-alkenes Using Vinylboronate Ester as a Platform
Keisuke Tonogaki, Kazuya Soga, Kenichiro Itami, Jun-ichi Yoshida
Synlett 2005, 1802-1804.

(66) Iron-Catalyzed Cross-Coupling of Alkenyl Sulfides with Grignard Reagents
Kenichiro Itami, Shohei Higashi, Masahiro Mineno, Jun-ichi Yoshida
Org. Lett. 2005, 7, 1219-1222.

(65) “Cation Pool” Method Based on C-C Bond Dissociation. Effective Generation of Monocations and Dications
Masayuki Okajima, Seiji Suga, Kenichiro Itami, Jun-ichi Yoshida
J. Am. Chem. Soc. 2005, 127, 6930-6931.

(64) Triarylethene-Based Extended π-Systems: Programmable Synthesis and Photophysical Properties
Kenichiro Itami, Youichi Ohashi, Jun-ichi Yoshida
J. Org. Chem. 2005, 70, 2778-2792.
Highlighted in “Heart Cut” of The American Chemical Society.

(63) Pyrimidine-Core Extended π-Systems: General Synthesis and Interesting Fluorescent Properties
Kenichiro Itami, Daisuke Yamazaki, Jun-ichi Yoshida
J. Am. Chem. Soc. 2004, 126, 15396-15397.

(62) Rapid Construction of Multisubstituted Olefin Structures Using Vinylboronate Ester Platform Leading to Highly Fluorescent Materials
Kenichiro Itami, Keisuke Tonogaki, Youichi Ohashi, Jun-ichi Yoshida
Org. Lett. 2004, 6, 4093-4096.
Selected as “Hot Paper” of The American Chemical Society. Most-Accessed Articles.

(61) Catalytic Carbometalation/Cross-Coupling Sequence Across Alkynyl(2-pyridyl)silanes Leading to a Diversity-Oriented Synthesis of Tamoxifen-type Tetrasubstituted Olefins
Toshiyuki Kamei, Kenichiro Itami, Jun-ichi Yoshida
Adv. Synth. Catal. 2004, 346, 1824-1835.

(60) The Carbon-Silicon Bond Cleavage of Organosilicon Compounds in Supercritical Water
Kenichiro Itami, Koji Terakawa, Jun-ichi Yoshida, Okitsugu Kajimoto
Bull. Chem. Soc. Jpn. 2004, 77, 2071-2080.
“Selected Paper” of The Chemical Society of Japan.

(59) Stereoselective Synthesis of Multisubstituted Butadienes through Directed Mizoroki-Heck Reaction and Homocoupling Reaction of Vinyl(2-pyridyl)silane
Kenichiro Itami, Yousuke Ushiogi, Toshiki Nokami, Youichi Ohashi, Jun-ichi Yoshida
Org. Lett. 2004, 6, 3695-3698.

(58) Sequential Assembly Strategy for Tetrasubstituted Olefin Synthesis Using Vinyl 2-Pyrimidyl Sulfide as a Platform
Kenichiro Itami, Masahiro Mineno, Nobuhiro Muraoka, Jun-ichi Yoshida
J. Am. Chem. Soc. 2004, 126, 11778-11779.
Highlighted in Nature Chemical Biology.

(57) Catalytic Intermolecular Pauson-Khand-type Reaction: Strong Directing Effect of Pyridylsilyl and Pyrimidylsilyl Groups and Isolation of Ru Complexes Relevant to Catalytic Reaction
Kenichiro Itami, Koichi Mitsudo, Kazuyoshi Fujita, Youichi Ohashi, Jun-ichi Yoshida
J. Am. Chem. Soc. 2004, 126, 11058-11066.
Highlighted in Angew. Chem. Int. Ed.

(56) Cationic Carbohydroxylation of Alkenes and Alkynes Using the Cation Pool Method
Seiji Suga, Yasuhisa Kageyama, Govindarajulu Babu, Kenichiro Itami, Jun-ichi Yoshida
Org. Lett. 2004, 6, 2709-2711.

(55) Stereoselective Synthesis of (Z)-1-Silyl-2-stannylethene by Palladium-Catalyzed Silastannation of Ethylene and Its Synthetic Transformations
Masahiro Murakami, Takanori Matsuda, Kenichiro Itami, Shinji Ashida, Miki Terayama
Synthesis 2004, 1522-1526.

(54) Aqueous Photo-Dimerization Using 2-Pyridylsilyl Group as a Removable Hydrophilic Group
Toshiki Nokami, Kenichiro Itami, Jun-ichi Yoshida
Chem. Lett. 2004, 33, 596-597.

(53) Phase Tag: Free from Solid Phase Synthesis
Kenichiro Itami, Jun-ichi Yoshida
Kagaku Frontier 2004, 14, 136-145.

(52) Diversity-Oriented Synthesis of Tamoxifen-type Tetrasubstituted Olefins
Kenichiro Itami, Toshiyuki Kamei, Jun-ichi Yoshida
J. Am. Chem. Soc. 2003, 125, 14670-14671.
Highlighted in Nature Chemical Biology, Current Opinion in Chemical Biology.

(51) Palladium-Catalyzed Rearrangement/Arylation of 2-Allyloxypyridine Leading to the Synthesis of N-Substituted 2-Pyridones
Kenichiro Itami, Daisuke Yamazaki, Jun-ichi Yoshida
Org. Lett. 2003, 5, 2161-2164.

(50) Efficient and Rapid C-Si Bond Cleavage in Supercritical Water
Kenichiro Itami, Koji Terakawa, Jun-ichi Yoshida, Okitsugu Kajimoto
J. Am. Chem. Soc. 2003, 125, 6058-6059.

(49) 2-Pyridyldimethylsilane
Jun-ichi Yoshida, Kenichiro Itami
Electronic Encyclopedia of Reagents for Organic Synthesis, Wiley, online.

(48) AgOAc-Catalyzed Aldehyde Allylation Using Allyldimethyl(2-pyridyl)silane
Kenichiro Itami, Toshiyuki Kamei, Masahiro Mineno, Jun-ichi Yoshida
Chem. Lett. 2002, 1084-1085.

(47) A General and Straightforward Route toward Diarylmethanes. Integrated Cross-Coupling Reactions Using (2-Pyridyl)silylmethylstannane as an Air-Stable, Storable, and Versatile Coupling Platform
Kenichiro Itami, Masahiro Mineno, Toshiyuki Kamei, Jun-ichi Yoshida
Org. Lett. 2002, 4, 3635-3638.

(46) Tag Strategy in Separation and Recovery
Jun-ichi Yoshida, Kenichiro Itami
Chem. Rev. 2002, 102, 3693-3716.

(45) A Pyridylsilyl Group Expands the Scope of Catalytic Intermolecular Pauson-Khand Reactions
Kenichiro Itami, Koichi Mitsudo, Jun-ichi Yoshida
Angew. Chem. Int. Ed. 2002, 41, 3481-3484.
Highlighted in Angew. Chem. Int. Ed., Kagaku.

(44) The Use of Hydrophilic Groups in Aqueous Organic Reactions
Kenichiro Itami, Jun-ichi Yoshida
Chem. Rec. 2002, 2, 213-224.

(43) Pyridylsilyl Group-Driven Cross-Coupling Reactions
Kenichiro Itami, Koichi Mitsudo, Toshiki Nokami, Toshiyuki Kamei, Tooru Koike, Jun-ichi Yoshida
J. Organomet. Chem. 2002, 653, 105-113.

(42) 2-Pyridyldimethylsilyl Group as a Removable Hydrophilic Group in Aqueous Organic Reactions: Formation of Molecular Aggregates and Dramatic Rate Enhancement in Diels-Alder Reactions
Kenichiro Itami, Toshiki Nokami, Jun-ichi Yoshida
Adv. Synth. Catal. 2002, 344, 441-451.

(41) Metal-Catalyzed Hydrosilylation of Alkenes and Alkynes Using Dimethyl(pyridyl)silane
Kenichiro Itami, Koichi Mitsudo, Akira Nishino, Jun-ichi Yoshida
J. Org. Chem. 2002, 67, 2645-2652.

(40) Silyl Peroxides
Kohei Tamao, Jun-ichi Yoshida, Kenichiro Itami
Science of Synthesis 2002, Category 1, Vol. 4, 413-425.

(39) [Bis(2-pyridyldimethylsilyl)methyl]lithium
Jun-ichi Yoshida, Kenichiro Itami
Electronic Encyclopedia of Reagents for Organic Synthesis, Wiley, online.

(38) Use of Molecular Aggregates as Nanoreaction Sites: New Synthetic Organic Chemistry in the Aqueous Phase
Jun-ichi Yoshida, Kenichiro Itami
Chemistry and Education 2002, 50, 121-124.

(37) Automation in Organic Synthesis and Development of New Methodologies and Strategies for Automated Synthesis
Jun-ichi Yoshida, Seiji Suga, Kenichiro Itami
Kagaku Kogyo 2002, 53, 6-12.

(36) Diversity-Oriented Synthesis of Multisubstituted Olefins through the Sequential Integration of Palladium-Catalyzed Cross-Coupling Reactions. 2-Pyridyldimethyl(vinyl)silane as a Versatile Platform for Olefin Synthesis
Kenichiro Itami, Toshiki Nokami, Yoji Ishimura, Koichi Mitsudo, Toshiyuki Kamei, Jun-ichi Yoshida
J. Am. Chem. Soc. 2001, 123, 11577-11585.
Highlighted in Eur. J. Org. Chem.

(35) Unusual Metal-Dependent Acceleration and Deceleration in the Metal-Catalyzed Hydrosilylation of Olefins Using Pyridyldimethylsilanes
Kenichiro Itami, Koichi Mitsudo, Akira Nishino, Jun-ichi Yoshida
Chem. Lett. 2001, 1088-1089.

(34) Pyridylsilyl Group as a Multifunctional Phase Tag for Solution-Phase Synthesis
Jun-ichi Yoshida, Kenichiro Itami
J. Synth. Org. Chem. Jpn. 2001, 59, 1086-1094.

(33) Silyl-Substituted Dithioles as Candidates for New Electron Donors
Hongqi Li, Keiji Nishiwaki, Kenichiro Itami, Jun-ichi Yoshida
Bull. Chem. Soc. Jpn. 2001, 74, 1717-1725.

(32) Unusually Accelerated Silylmethyl Transfer from Tin in Stille Coupling: Implication of Coordination-Driven Transmetalation
Kenichiro Itami, Toshiyuki Kamei, Jun-ichi Yoshida
J. Am. Chem. Soc. 2001, 123, 8773-8779.

(31) Regioselective Catalytic Allylic Alkylation Directed by Removable 2-PyMe₂Si Group
Kenichiro Itami, Tooru Koike, Jun-ichi Yoshida
J. Am. Chem. Soc. 2001, 123, 6957-6958.

(30) Palladium-Catalyzed Cross-Coupling Reaction of Alkenyldimethyl(2-pyridyl)silanes with Organic Halides: Complete Switch from the Carbometalation Pathway to the Transmetalation Pathway
Kenichiro Itami, Toshiki Nokami, Jun-ichi Yoshida
J. Am. Chem. Soc. 2001, 123, 5600-5601.

(29) Pyridyl Group Assisted Deprotonation of a Methyl Group on Silicon: Complex Induced Proximity Effect and Novel Hydroxymethylation
Kenichiro Itami, Toshiyuki Kamei, Koichi Mitsudo, Toshiki Nokami, Jun-ichi Yoshida
J. Org. Chem. 2001, 66, 3970-3976.

(28) Directed Intermolecular Carbomagnesation Across Vinylsilane: 2-PyMe₂Si Group as a Removable Directing Group
Kenichiro Itami, Koichi Mitsudo, Jun-ichi Yoshida
Angew. Chem. Int. Ed. 2001, 40, 2337-2339.

(27) Facile Generation of [Bis(2-pyridyldimethylsilyl)methyl]lithium and Its Reaction with Carbonyl Compounds. New Method for the Stereoselective Synthesis of Vinylsilanes
Kenichiro Itami, Toshiki Nokami, Jun-ichi Yoshida
Tetrahedron 2001, 57, 5045-5054.

(26) 2-Pyridyldimethylsilyl as a Removable Hydrophilic Group in Aqueous Diels-Alder Reaction
Kenichiro Itami, Toshiki Nokami, Jun-ichi Yoshida
Angew. Chem. Int. Ed. 2001, 40, 1074-1076.

(25) Highly Efficient Carbopalladation Across Vinylsilane: Dual Role of the 2-PyMe₂Si Group as a Directing Group and as a Phase Tag
Kenichiro Itami, Koichi Mitsudo, Toshiyuki Kamei, Tooru Koike, Toshiki Nokami, Jun-ichi Yoshida
J. Am. Chem. Soc. 2000, 122, 12013-12014.

(24) Palladium-Catalysed Asymmetric [4+2] Cycloaddition of Vinylallene with 1,3-Diene
Masahiro Murakami, Ryo Minamida, Kenichiro Itami, Masaya Sawamura, Yoshihiko Ito
Chem. Commun. 2000, 2293-2294.

(23) [Bis(2-pyridyldimethylsilyl)methyl]lithium. New Reagent for the Stereoselective Synthesis of Vinylsilanes
Kenichiro Itami, Toshiki Nokami, Jun-ichi Yoshida
Org. Lett. 2000, 2, 1299-1302.

(22) New Cycloaddition Reactions Mediated by Transition Metals
Masahiro Murakami, Kenichiro Itami, Yoshihiko Ito
Kikan Kagaku Sosetsu 2000, 47, 19-28.

(21) Oxidation of 2-Pyridyldimethylsilyl Group to Hydroxyl Group by H₂O₂/KF. Implication of Fluoride Ion Accelerated 2-Pyridyl-Silyl Bond Cleavage
Kenichiro Itami, Koichi Mitsudo, Jun-ichi Yoshida
J. Org. Chem. 1999, 64, 8709-8714.

(20) (2-Pyridyldimethylsilyl)methyl Lithium as a Novel Hydroxymethylating Reagent
Kenichiro Itami, Koichi Mitsudo, Jun-ichi Yoshida
Tetrahedron Lett. 1999, 40, 5537-5540.

(19) Facile Generation of a-Silyl Carbanion of Trimethylsilyl Group Assisted by Intramolecular Pyridyl Group Coordination
Kenichiro Itami, Koichi Mitsudo, Jun-ichi Yoshida
Tetrahedron Lett. 1999, 40, 5533-5536.

(18) Construction of Eight-Membered Carbocycles by Palladium-Catalyzed [4+4] Cycloaddition of Vinylallenes
Masahiro Murakami, Kenichiro Itami, Yoshihiko Ito
Synlett 1999, 951-953.

(17) Catalytic Asymmetric [4+1] Cycloaddition of Vinylallenes with Carbon Monoxide: Reversal of the Induced Chirality by the Choice of Metal
Masahiro Murakami, Kenichiro Itami, Yoshihiko Ito
J. Am. Chem. Soc. 1999, 121, 4130-4135.

(16) 2-Pyridylsilyl Group as a Multifunctional “Phase Tag” for Solution Phase Synthesis
Jun-ichi Yoshida, Kenichiro Itami, Koichi Mitsudo, Seiji Suga
Tetrahedron Lett. 1999, 40, 3403-3406.

(15) Coordination Modes and Catalytic Carbonylative [4+1] Cycloaddition of Vinylallenes
Masahiro Murakami, Kenichiro Itami, Yoshihiko Ito
Organometallics 1999, 18, 1326-1336.

(14) Nickel-Catalyzed Cross-Coupling of Dienyl Phosphates with Grignard Reagents in the Synthesis of 2-Substituted 1,3-Dienes
Sofia E. Karlstrom, Kenichiro Itami, Jan-E. Bäckvall
J. Org. Chem. 1999, 64, 1745-1749.

(13) New Cycloaddition Reactions of Conjugated Allenes Catalyzed by Transition Metal Complexes
Masahiro Murakami, Kenichiro Itami, Minoru Ubukata, Itaru Tsuji, Yoshihiko Ito
J. Synth. Org. Chem. Jpn. 1998, 56, 406-412.

(12) Single-Step Construction of a Nine-Membered Carbocycle by a New [4+4+1] Cycloaddition
Masahiro Murakami, Kenichiro Itami, Yoshihiko Ito
Angew. Chem. Int. Ed. 1998, 37, 3418-3420.

(11) Rhodium-Catalyzed Intermolecular [4+2] Cycloaddition of Unactivated Substrates
Masahiro Murakami, Minoru Ubukata, Kenichiro Itami, Yoshihiko Ito
Angew. Chem. Int. Ed. 1998, 37, 2248-2250.

(10) Chiral Benzoquinones as New Class of Ligands for Asymmetric Catalysis: Synthesis and Application to the Palladium(II)-Catalyzed 1,4-Dialkoxylation of 1,3-Dienes
Kenichiro Itami, Andreas Palmgren, Atli Thorarensen, Jan-E. Bäckvall
J. Org. Chem. 1998, 63, 6466-6471.

(9) Unsymmetrical Functionalization of 1,3-Cyclohexadienes: Palladium-Catalyzed Stereoselective 1,4-Acyloxy-Alkoxylation
Eike Hupe, Kenichiro Itami, Attila Aranyos, Kalman J. Szabo, Jan-E. Bäckvall
Tetrahedron 1998, 54, 5375-5384.

(8) Palladium-Catalyzed Intramolecular 1,4-Dialkoxylation of Cyclohexadienes: An Efficient Route to Highly Stereocontrolled Oxygen Heterocycles
Kenichiro Itami, Andreas Palmgren, Jan-E. Bäckvall
Tetrahedron Lett. 1998, 39, 1223-1226.

(7) Iridium-Catalyzed [5+1] Cycloaddition: Allenylcyclopropane as a Five-Carbon Assembling Unit
Masahiro Murakami, Kenichiro Itami, Minoru Ubukata, Itaru Tsuji, Yoshihiko Ito
J. Org. Chem. 1998, 63, 4-5.

(6) Palladium(II)-Catalyzed Asymmetric 1,4-Oxidation of 2-Phenyl-1,3-Cyclohexadiene
Atli Thorarensen, Andreas Palmgren, Kenichiro Itami, Jan-E. Bäckvall
Tetrahedron Lett. 1997, 38, 8541-8544.

(5) Directed Intermolecular [4+2] Cycloaddition of Unactivated 1,3-Diene Substrates with High Regio- and Stereoselectivities
Masahiro Murakami, Kenichiro Itami, Yoshihiko Ito
J. Am. Chem. Soc. 1997, 119, 7163-7164.

(4) Rhodium-Catalyzed Asymmetric [4+1] Cycloaddition
Masahiro Murakami, Kenichiro Itami, Yoshihiko Ito
J. Am. Chem. Soc. 1997, 119, 2950-2951.

(3) Synthesis of (Vinylallene)rhodium(III) Complex of Planar Structure: Perfect p®s Conversion of 1,3-Diene System
Masahiro Murakami, Kenichiro Itami, Yoshihiko Ito
J. Am. Chem. Soc. 1996, 118, 11672-11673.

(2) A Study on Rhodium-Vinylallene Complexes Leading to a New Reaction, Rhodium-Catalyzed Carbonylative [4+1] Cycloaddition
Masahiro Murakami, Kenichiro Itami, Yoshihiko Ito
Angew. Chem. Int. Ed. Engl. 1995, 34, 2691-2694.

(1) A Remarkable Effect of Silyl Substitution on Electrocyclization of Vinylallenes
Masahiro Murakami, Hideki Amii, Kenichiro Itami, Yoshihiko Ito
Angew. Chem. Int. Ed. Engl. 1995, 34, 1476-1477.

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