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Photoredox‐Catalyzed Decarboxylative Oxidation of Arylacetic Acids

Yota Sakakibara, Phillippa Cooper, Kei Murakami, Kenichiro Itami
Chem. Asian J.
2018, Early view. DOI:10.1002/asia.201800529.

A photoredox‐catalyzed decarboxylative oxidation of arylacetic acids, which are privileged scaffolds in pharmaceuticals, is reported herein. The established method is operationally simple and a variety of substrates are applicable, providing rapid access to dehomologated bioisosteres of common pharmaceuticals.

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