Blog

Iridium Catalysis for C-H Bond Arylation of Heteroarenes with Iodoarenes

Benoit Join, Takuya Yamamoto, and Kenichiro Itami
Angew. Chem. Int. Ed. 2009, 48, 3644.

DOI: 10.1002/anie.200806358

Efficient couplings

using equimolar quantities of each coupling partner and multiple C-H bond arylation reactions are achieved with an Ir-based catalytic system for the C-H bond arylation of electron-rich heteroarenes with iodoarenes to construct extended pai-systems. The dramatic ligand effect on reaction efficiency leads to the discovery that Crabtree’s catalyst (see scheme) is the optimal catalyst precursor.

Related post

  1. Synthesis of Thiophene-Based TAK…
  2. Oxidative Homocoupling Reaction …
  3. カーボンナノリング:最短のカーボンナノチューブ
  4. An axially chiral 1,1′-biazulene…
  5. Diversity-oriented synthesis of …
  6. Mechanistic Studies on the Pd-ca…
  7. C-H Activation Enables Rapid Str…
  8. Bare aromatic polymers synthesiz…

最近の記事

Flickr@Itamilab

天池先輩からコーヒースープ伴夫妻からのお歳暮です!潤さん、宮村さん、ありがとうございます!!武藤さん、ビールありがとうございます!平賀大都わーいやなさん、あつしさん、ありがとうございます!!だいぶ前だけど、Stripes look #ootdHalloween lookラインを洗う時ですら格好良く。戸谷先生教育実習!imageけいしゅう、誕生日おめでとう!誕生日は英吉家!!3年生に名古屋ぼろ勝ちアピール中!!アリシア卒業おめでとう女子会!
PAGE TOP