ブログ

Diversity-oriented synthesis of nanographenes enabled by dearomative annulative π-extension

Diversity-oriented synthesis of nanographenes enabled by dearomative annulative π-extension

Wataru Matsuoka, Hideto Ito,* David Sarlah,* Kenichiro Itami*

Nature Commun. 2021, 12, 3940. DOI: 10.1038/s41467-021-24261-y [open access]

Nanographenes and polycyclic aromatic hydrocarbons (PAHs) are among the most important classes of compounds, with potential applications in nearly all areas of science and tech- nology. While the theoretically possible number of nanographene structures is extraordinary, most of these molecules remain synthetically out of reach due to a lack of programmable and diversity-oriented synthetic methods, and their potentially huge structure-property diversity has not been fully exploited. Herein we report a diversity-oriented, growth-from-template synthesis of nanographenes enabled by iterative annulative π-extension (APEX) reactions from small PAH starting materials. The developed dearomative annulative π-extension (DAPEX) reaction enables π-elongation at the less-reactive M-regions of PAHs, and is suc- cessfully combined with complementary APEX reactions that occur at K- and bay-regions to access a variety of previously untapped nanographenes.

関連記事

  1. Selective Introduction of Organi…
  2. アダマンタン縮環アレーン
  3. Concise Syntheses of Dictyodendr…
  4. Synthesis of Extended π-Systems …
  5. MEDCHEM NEWS 28-2号 創薬最前線 –…
  6. Palladium-free synthesis of [10]…
  7. [9]Cycloparaphenylene: Nickel-Me…
  8. Reversible modulation of circadi…

最近の記事

Flickr@Itamilab

天池先輩からコーヒースープ伴夫妻からのお歳暮です!潤さん、宮村さん、ありがとうございます!!武藤さん、ビールありがとうございます!平賀大都わーいやなさん、あつしさん、ありがとうございます!!だいぶ前だけど、Stripes look #ootdHalloween lookラインを洗う時ですら格好良く。戸谷先生教育実習!imageけいしゅう、誕生日おめでとう!誕生日は英吉家!!3年生に名古屋ぼろ勝ちアピール中!!アリシア卒業おめでとう女子会!
PAGE TOP