English
Synthesis of A Heptaarylisoquinoline: Unusual Disconnection for Constructing Isoquinoline Frameworks
In a novel disconnection of isoquinoline ring synthesis at the C7–C8/C4a–C8a bonds, these bonds can be formed by a [4+2] cycloaddition between thiophene S,S-dioxide and alkynes. With a subsequent C–H arylation of the resulting hexaarylisoquinoline at the C3 position, the synthesis of a fully substituted isoquinoline has been achieved.
今年３月に博士を取得して卒業した鈴木真くんのお仕事です！マルチアリールベンゼン合成を応用して、ヘキサアリールイソキノリン合成を達成しました。
