Blog

A General Catalyst for the b-Selective C–H Bond Arylation of Thiophenes with Iodoarenes

K. Ueda, S. Yanagisawa,  J. Yamaguchi, K. Itami

Angew. Chem. Int. Ed. 2010, ASAP. DOI; 10.1002/anie.201005082

β-Selective C–H Bond Arylation of Thiophenes

The normally less reactive β position of thiophenes was previously inaccessible to direct functionalization. However, the β selectivity observed with the catalytic system PdCl2/P{OCH(CF3)2}3/Ag2CO3 in the arylation of thiophenes with iodoarenes (see scheme) is a remarkably general phenomenon applicable to unsubstituted, monosubstituted, and disubstituted thiophene derivatives, as well as thiophene-containing fused aromatic compounds.

 

Related post

  1. カーボンナノリング:最短のカーボンナノチューブ
  2. tert-Butoxide-Mediated C-H Bond …
  3. Hindered Biaryls by C–H Coupling…
  4. Exciton Recombination Dynamics i…
  5. Annulative π-Extension (APEX) of…
  6. Carbon Nanobelts: Brief History …
  7. Synthesis and Structural Feature…
  8. Chemical synthesis of carbon nan…

最近の記事

Flickr@Itamilab

天池先輩からコーヒースープ伴夫妻からのお歳暮です!潤さん、宮村さん、ありがとうございます!!武藤さん、ビールありがとうございます!平賀大都わーいやなさん、あつしさん、ありがとうございます!!だいぶ前だけど、Stripes look #ootdHalloween lookラインを洗う時ですら格好良く。戸谷先生教育実習!imageけいしゅう、誕生日おめでとう!誕生日は英吉家!!3年生に名古屋ぼろ勝ちアピール中!!アリシア卒業おめでとう女子会!
PAGE TOP