Blog

Dehydrogenative Synthesis of 2,2′-Bipyridyls through Regioselective Pyridine Dimerization

“Dehydrogenative Synthesis of 2,2′-Bipyridyls through Regioselective Pyridine Dimerization”
Shuya Yamada, Takeshi Kaneda, Philip Steib, Kei Murakami,* Kenichiro Itami*
Angew. Chem., Int. Ed. 2019, 58, 8341–8345.DOI:10.1002/anie.201814701.

The palladium-catalyzed dehydrogenative dimerization of pyridines is described. The dimerization reaction takes place smoothly to provide the corresponding 2,2′-bipyridyls with excellent C2-selectivity. The present protocol allows a concise synthesis of twisted 3,3′-disubstituted-2,2′-bipyridyls that is hitherto difficult to access with conventional methods.

Related post

  1. Synthesis of a Möbius carbon nan…
  2. Synthesis and Properties of [8]-…
  3. Nickel-Catalyzed C-H Arylation o…
  4. Lithium-mediated mechanochemical…
  5. Annulative π-Extension of Indole…
  6. (日本語) Direct Coupling of Naphtha…
  7. Synthesis, Properties, and Packi…
  8. Synthesis of partially and fully…

最近の記事

Flickr@Itamilab

天池先輩からコーヒースープ伴夫妻からのお歳暮です!潤さん、宮村さん、ありがとうございます!!武藤さん、ビールありがとうございます!平賀大都わーいやなさん、あつしさん、ありがとうございます!!だいぶ前だけど、Stripes look #ootdHalloween lookラインを洗う時ですら格好良く。戸谷先生教育実習!imageけいしゅう、誕生日おめでとう!誕生日は英吉家!!3年生に名古屋ぼろ勝ちアピール中!!アリシア卒業おめでとう女子会!
PAGE TOP