Blog

Dehydrogenative Synthesis of 2,2′-Bipyridyls through Regioselective Pyridine Dimerization

“Dehydrogenative Synthesis of 2,2′-Bipyridyls through Regioselective Pyridine Dimerization”
Shuya Yamada, Takeshi Kaneda, Philip Steib, Kei Murakami,* Kenichiro Itami*
Angew. Chem., Int. Ed. 2019, 58, 8341–8345.DOI:10.1002/anie.201814701.

The palladium-catalyzed dehydrogenative dimerization of pyridines is described. The dimerization reaction takes place smoothly to provide the corresponding 2,2′-bipyridyls with excellent C2-selectivity. The present protocol allows a concise synthesis of twisted 3,3′-disubstituted-2,2′-bipyridyls that is hitherto difficult to access with conventional methods.

Related post

  1. Synthesis, Structure, and Reacti…
  2. tert-Butoxide-Mediated C-H Bond …
  3. Carbon Nanosheets by Morphology-…
  4. Synthesis and Size-Dependent Pro…
  5. Rapid Access to Kinase Inhibitor…
  6. Rapid access to polycyclic thiop…
  7. Topological molecular nanocarbon…
  8. Synthesis of Polybenzoacenes: An…

Twitter@Itami Lab

Itami Lab Facebook

Instagram@Itami Lab

最近の記事

Flickr@Itamilab

天池先輩からコーヒースープ伴夫妻からのお歳暮です!潤さん、宮村さん、ありがとうございます!!武藤さん、ビールありがとうございます!平賀大都わーいやなさん、あつしさん、ありがとうございます!!だいぶ前だけど、Stripes look #ootdHalloween lookラインを洗う時ですら格好良く。戸谷先生教育実習!imageけいしゅう、誕生日おめでとう!誕生日は英吉家!!3年生に名古屋ぼろ勝ちアピール中!!アリシア卒業おめでとう女子会!
PAGE TOP