Blog

Nickel-Catalyzed C-H Arylation of Azoles with Haloarenes: Scope, Mechanism, and Applications to the Synthesis of Bioactive Molecules

Takuya Yamamoto, Kei Muto, Masato Komiyama, Jerôme Canivet, Junichiro Yamaguchi, and Kenichiro Itami*

Chem. Eur. J2011, Early View

DOI: 10.1002/chem.201101091

New couples:

Novel Ni-based catalytic systems for the -H arylation of azoles with haloarenes have been developed (see scheme). Mechanistic studies as well as applications to the synthesis of biologically active com- pounds (febuxostat, tafamidis, and texaline) are also described.

Related post

  1. MEDCHEM NEWS 28-2 Merging synthe…
  2. Nickel-Catalyzed C−H/C−O Couplin…
  3. Selective Synthesis of [7]- and …
  4. Mechanistic Studies on the Pd-ca…
  5. Key Structural Elements of Unsym…
  6. Exciton Recombination Dynamics i…
  7. Regioselective Unsymmetrical Tet…
  8. The AMOR Arabinogalactan Sugar C…

Twitter@Itami Lab

Itami Lab Facebook

Instagram@Itami Lab

This error message is only visible to WordPress admins

Error: API requests are being delayed. New posts will not be retrieved.

There may be an issue with the Instagram access token that you are using. Your server might also be unable to connect to Instagram at this time.

Error: API requests are being delayed for this account. New posts will not be retrieved.

There may be an issue with the Instagram access token that you are using. Your server might also be unable to connect to Instagram at this time.

Error: No posts found.

Make sure this account has posts available on instagram.com.

Click here to troubleshoot

最近の記事

Flickr@Itamilab

天池先輩からコーヒースープ伴夫妻からのお歳暮です!潤さん、宮村さん、ありがとうございます!!武藤さん、ビールありがとうございます!平賀大都わーいやなさん、あつしさん、ありがとうございます!!だいぶ前だけど、Stripes look #ootdHalloween lookラインを洗う時ですら格好良く。戸谷先生教育実習!imageけいしゅう、誕生日おめでとう!誕生日は英吉家!!3年生に名古屋ぼろ勝ちアピール中!!アリシア卒業おめでとう女子会!
PAGE TOP