Blog

Synthesis of Octaaryl Naphthalenes and Anthracenes with Different Substituents

Shin Suzuki, Kenichiro Itami,* Junichiro Yamaguchi*

Angew. Chem., Int. Ed. 2017, Accepted article. DOI: 10.1002/anie.201709332

A synthesis of multiply arylated naphthalenes and anthracenes with eight different substituents has been accomplished. The key intermediate is a tetraarylthiophene S-oxides, which is synthesized by a protocol involving sequential C–H arylation and cross-coupling from 3-methoxythiophene, followed by oxidation of the sulfur atom. The resulting tetraarylthiophene S-oxide can be converted to a tetraaryl benzynes or naphthalynes, then merged via a [4+2] cycloaddition reaction with another tetraarylthiophene S-oxide, resulting in the programmed synthesis of octaarylnaphthalene and octaarylanthracene.

Related post

  1. Selective Synthesis of [7]- and …
  2. Synthesis and Properties of [9]C…
  3. Design and Synthesis of Carbon N…
  4. Rapid Access to Kinase Inhibitor…
  5. Corannulene–Helicene Hybrids: Ch…
  6. One-Step Annulative π-Extension …
  7. [9]Cycloparaphenylene: Nickel-Me…
  8. Annulative π-Extension (APEX): A…

Twitter@Itami Lab

Itami Lab Facebook

Instagram@Itami Lab

最近の記事

Flickr@Itamilab

天池先輩からコーヒースープ伴夫妻からのお歳暮です!潤さん、宮村さん、ありがとうございます!!武藤さん、ビールありがとうございます!平賀大都わーいやなさん、あつしさん、ありがとうございます!!だいぶ前だけど、Stripes look #ootdHalloween lookラインを洗う時ですら格好良く。戸谷先生教育実習!imageけいしゅう、誕生日おめでとう!誕生日は英吉家!!3年生に名古屋ぼろ勝ちアピール中!!アリシア卒業おめでとう女子会!
PAGE TOP