Blog

Polycyclic Arene Synthesis by Annulative π-Extension

J. Am. Chem. Soc., in press.
Hideto Ito, Yasutomo Segawa, Kei Murakami, Kenichiro Itami*
DOI: 10.1021/jacs.8b09232

Perspective Paper  on Our APEX Chemistry
Annulative π-extension (APEX) has emerged as a powerful and efficient synthetic method for the construction of polycyclic aromatic hydrocarbons, nanographenes, and π-extended fused heteroarenes. In contrast to classical multi-step syntheses requiring substrate prefunctionalization, APEX reactions minimize the number of preparative steps by direct C-H activation of small aromatic templates. In this perspective, we review recently reported APEX reactions to shed light on the utility, scope, and promise of this approach for next-generation syntheses of polycyclic arenes.

Related post

  1. Rapid Access to Nanographenes an…
  2. Isolation, Structure, and Reacti…
  3. Phenanthro[9,10-a]corannulene by…
  4. Size-Selective Complexation and …
  5. Photo-induced arylation of carba…
  6. Synthesis and Structural Feature…
  7. Decarbonylative C–H Coupling of …
  8. A grossly warped nanographene an…

最近の記事

Flickr@Itamilab

天池先輩からコーヒースープ伴夫妻からのお歳暮です!潤さん、宮村さん、ありがとうございます!!武藤さん、ビールありがとうございます!平賀大都わーいやなさん、あつしさん、ありがとうございます!!だいぶ前だけど、Stripes look #ootdHalloween lookラインを洗う時ですら格好良く。戸谷先生教育実習!imageけいしゅう、誕生日おめでとう!誕生日は英吉家!!3年生に名古屋ぼろ勝ちアピール中!!アリシア卒業おめでとう女子会!
PAGE TOP