(43) The dynamics of strigolactone perception in Striga hermonthica : a working hypothesis
Yuichiro Tsuchiya,* Masahiko Yoshimura, Shinya Hagihara
J. Exp. Botany 2018, Just Accepted. DOI: 10.1093/jxb/ery061
(42) Discovery of shoot branching regulator targeting strigolactone re-ceptor DWARF14
Masahiko Yoshimura, Ayato Sato, Keiko Kuwata, Yoshiaki Inukai, Toshinori Kinoshita, Kenichiro Itami, Yuichiro Tsuchiya, and Shinya Hagihara
ACS Central Science, 2018, 4, 230-234. DOI: 10.1021/acscentsci.7b00554
(41) Chemical hijacking of auxin signaling with an engineered auxin-TIR1 pair
Naoyuki Uchida, Koji Takahashi, Rie Iwasaki, Ryotaro Yamada, Masahiko Yoshimura, Takaho A. Endo, Seisuke Kimura, Hua Zhang, Mika Nomoto, Yasuomi Tada, Toshinori Kinoshita, Kenichiro Itami, Shinya Hagihara*, and Keiko U. Torii*
Nat. Chem. Biol., 2018, 14, 299-307. DOI: 10.1038/nCHeMBIO.2555
(40) Discovery of Synthetic Small Molecules that Enhance the Number of Stomata: C-H Functionalization Chemistry for Plant Biology
Asraa Ziadi, Nayuki Uchida, Hiroe Kato, Rina Hisamatsu, Ayato Sato, Shinya Hagihara, Kenichiro Itami and Keiko U. Torii
Chem. Commun., 2017, 53, 9632-9635.
(39) Key Structural Elements of Unsymmetrical Cyanine Dyes for Highly Sensitive Fluorescence Turn-On DNA Probes
Kakishi Uno, Taeko Sasaki, Nagisa Sugimoto, Hideto Ito, Taishi Nishihara, Shinya Hagihara, Tetsuya Higashiyama, Narie Sasaki, Yoshikatsu Sato, Kenichito Itami
Chem. Asian. J. 2017, 12, 233-238.
(38) High-throughput Assay for Quantification of Aminoglycoside–Ribosome Interaction
Shun Yamashita, Dominik Bergmann, Ayato Sato, Mika Nomoto, Yasuomi Tada, Hans-Ulrich Humpf, Kenichiro Itami and Shinya Hagihara
Chem. Lett. 2016, 45, 1048-1050. DOI:10.1246/cl.160508
(37) Making Dimethylamino a Transformable Directing Group by Nickel‐Catalyzed C-N Borylation
Hua Zhang, Shinya Hagihara, and Kenichiro Itami
Chem. Eur. J. 2015 21, 16796-16800. DOI: 10.1002/chem.201503596
(36) Probing strigolactone receptors in Striga hermonthica with fluorescence
Yuichiro Tsuchiya, Masahiko Yoshimura, Yoshikatsu Sato, Keiko Kuwata, Shigeo Toh, Duncan Holbrook-Smith, Hua Zhang, Peter McCourt, Kenichiro Itami, Toshinori Kinoshita, Shinya Hagihara
Science 2015, 349, 864-868. DOI: 10.1126/science.aab3831.
(35) Aromatic C-H Borylation by Nickel Catalysis
Hua Zhang, Shinya Hagihara, Kenichiro Itami
Chem. Lett. 2015, 44 (6), 779-781. DOI: 10.1246/cl.150154.
(34) Development of the crosslinking reactions to RNA triggered by oxidation
Kusano, S.; Haruyama, T.; Ishiyama, S.; Hagihara, S.; Nagatsugi, F.,
Chem. Commun. 2014, 50 (30), 3951-3954. DOI: 10.1039/c3cc49463b.
(33) The Crosslink Formation of 2′-OMe Oligonucleotide Containing 2-Amino-6-vinylpurine Protects mRNA from miRNA-Mediated Silencing
Shinya Hagihara, Wei-Chen Lin, Shuhei Kusano, Xiao-guang Chao, Tsuneaki Hori, Shuhei Imoto, and Fumi Nagatsugi
Chembiochem 2013, 14 (12), 1427-1429. DOI: 10.1002/cbic.201300382.
(32) Synthesis of peptide-conjugated light-driven molecular motors and evaluation of their DNA-binding properties
Fumi Nagatsugi, Yousuke Takahashi, Maiko Kobayashi, Shunsuke Kuwahara, Suhei Kusano, Tomoko Chikuni, Shinya Hagihara, Nobuyuki Harada.
Molecular Biosystems 2013, 9 (5), 969-973. DOI: 10.1039/c2mb25520k.
(31) Synthesis of 6-amino-2-vinylpurine derivatives for cross-linking and evaluation of the reactivity
Suhei Kusano, Tomoya Sakuraba, Shinya Hagihara, Fumi Nagatsugi
Bioorg. Med. Chem. Lett., 2012, 22, 6957-6961. DOI: 10.1016/j.bmcl.2012.08.122.
(30) Production of truncated protein by the crosslink formation of mRNA with 2′-OMe oligoribonucleotide containing 2-amino-6-vinylpurine
Shinya Hagihara, Tsuneaki Hori, Suhei Kusano, Shuhei Imoto, WeiChen Lin, XiaoGuang Chao, Fumi Nagatsugi
Bioorg. Med. Chem. Lett., 2012, 22, 3870-3872.
(29) Dependency of the cross-linking reactivity with 2-amino-6-vinylpurine on the neighboring bases
Fumi Nagatsugi, Shinya Hagihara, Shuhei Kusano, Xiau-guang Chao
Nucleic Acid Therapeutics, 2012, 21, 37.
(28) Alteration of cross-linking selectivity with the 2′-OMe analogue of 2-amino-6-vinylpurine and evaluation of antisense effects
Shuhei Imoto, Tsuneaki Hori, Shinya Hagihara, Yousuke Taniguchi, Shigeki Sasaki, Fumi Nagatsugi
Bioorg. Med. Chem. Lett., 2010, 20, 6121-6124.
(27) Hydrazinoanthrylboronic acids as supramolecular exciton-coupled circular dichroism (ECCD) probes for multivalent catechols, particularly epigallocatechin gallate
Andreas Henning, Shinya Hagihara, Stefan Matile
Chirality, 2009, 21, 826-835.
(26) Systematic synthesis and inhibitory activity of haloacetamidyl oligosaccharide derivatives toward cytoplasmic peptide:N-glycanase
Ayako Miyazaki, Ichiro Matsuo, Shinya Hagihara, Ayako Kakegawa, Tadashi Suzuki, Yukishige Ito.
Glycoconj. J., 2009, 26, 133-140.
(25) Screening of -basic naphthalene and anthracene amplifiers for -acidic synthetic pore sensors
Shinya Hagihara, Ludovic Gremaud, Guillaume Bollot, Jiri Mareda, Stefan Matile
J. Am. Chem. Soc., 2008, 130, 4347-4351.
(24) Signal amplification by conjugate addition for differential sensing with synthetic pores
Shinya Hagihara, Hiroyuki Tanaka, Stefan Matile
Org. Biomol. Chem., 2008, 6, 2259-2262.
(23) Boronic acid converters for reactive hydrazide amplifiers: polyphenol sensing in green tea with synthetic pores
Shinya Hagihara, Hiroyuki Tanaka, Stefan Matile
J Am. Chem. Soc., 2008, 130, 5656-5657.
(22) Artificial tongues and leaves
Shinya Hagihara, Stefan Matile, Naomi Sakai, et. al.
Pure Appl. Chem., 2008, 80, 1873-1882.
(21) Small-molecule binding to the nonquadruplex form of the human telomeric sequence
Yuki Goto, Shinya Hagihara, Masaki Hagihara, Kazuhiko Nakatani
ChemBioChem, 2007, 8, 723-726.
(20) Analysis of ER-associated glycoprotein degradation using synthetic glycopeptide probes
Shinya Hagihara, Kazuhito Goda, Ichiro Matsuo, Yukishige Ito
Biochem. Biophys. Res. Commun., 2007, 360, 357–362.
(19) Fluorescently labeled inhibitor for profiling cytoplasmic peptide:N-glycanase”
Shinya Hagihara, Ayako Miyazaki, Ichiro Matsuo, Atsushi Tatami, Tadashi Suzuki, Yukishige Ito
Glycobiology, 2007, 17, 1070-1076.
(18) Evaluation of mismatch-binding ligands as inhibitors for Rev–RRE interaction
Kazuhiko Nakatani, Souta Horie, Yuki Goto, Akio Kobori, Shinya Hagihara
Bioorg. Med. Chem., 2006, 14, 5384-5388. DOI: 10.1016/j.bmc.2006.03.038.
(17) Small-molecule ligand induces nucleotide flipping in (CAG)n trinucleotide repeats
Kazuhiko Nakatani, Shinya Hagihara, Yuki Goto, Akio Kobori, Masaki Hagihara, Gosuke Hayashi, Motoki Kyo, Makoto Nomura, Masaki Mishima, Chojiro Kojima
Nature Chemical Biology, 2005, 1, 39-43. DOI: 10.1038/nchembio708.
(16) Thermodynamic analysis of interactions between N-linked sugar chains and F-box protein Fbs1
Shinya Hagihara, Kiichiro Totani, Ichiro Matsuo, Yukishige Ito
J. Med. Chem., 2005, 48, 3126-3129.
(15) Design and synthesis of oligosaccharides that interfere with glycoprotein quality-control systems
Midori A. Arai, Ichiro Matsuo, Shinya Hagihara, Kiichiro Totani, Jun-ichi Maruyama, Katsuhiko Kitamoto, Yukishige Ito
ChemBioChem, 2005, 6, 2281-2289.
(14) NMR structural analysis of the GG mismatch DNA complexed with naphthyridine dimer
Makoto Nomura, Shinya Hagihara, Yuki Goto, Kazuhiko Nakatani, Chojiro Kojima
Nucleic Acids Symp. Ser., 2005, 49, 213-214.
(13) Solution structure of a small-molecular ligand complexed with CAG trinucleotide repeat DNA
Kazuhiko Nakatani, Shinya Hagihara, Yuki Goto, Akio Kobori, Masaki Hagihara, Gosuke Hayashi, Masaki Kyo, Makoto Nomura, Masaki Mishima, Chojiro Kojima
Nucleic Acids Symp. Ser., 2005, 49, 49-50.
(12) Synthesis of fluorine substituted oligosaccharide analogues of monoglucosylated glycan chain, a proposed ligand of lectin-chaperone calreticulin and calnexin
Yukishige Ito, Shinya Hagihara, Midori A. Arai, Ichiro Matsuo, Maki Takatani
Glycoconj. J., 2004, 21, 257-266.
(11) Synthesis of glycoprotein molecular probes for the analyses of protein quality control system
Kiichiro Totani, Ichiro Matsuo, Maki Takatani, Midori A. Arai, Shinya Hagihara, Yukishige Ito
Glycoconj. J., 2004, 21, 69-74. DOI: 10.1023/B:GLYC.0000043751.18027.c1.
(10) Detection of guanine–adenine mismatches by surface plasmon resonance sensor carrying naphthyridine–azaquinolone hybrid on the surface
Shinya Hagihara, Hiroyuki Kumasawa, Yuki Goto, Gosuke Hayashi, Akio Kobori, Isao Saito, Kazuhiko Nakatani
Nucleic Acids Res., 2004, 32, 278-286.
(9) Synthesis of asparagine-linked glycan chains: Toward understanding glycoprotein quality control
Ichiro Matsuo, Shinya Hagihara, Kiichiro Totani, Toshinori Kashiwagi, Yukishige Ito
Glycobiology, 2004, 14, 1081-1082.
(8) Thermodynamic analysis for the sugar recognition of Fbs1
Shinya Hagihara, Kiichiro Totani, Ichiro Matsuo, Yukishige Ito
Glycobiology, 2004, 14, 1096-1096.
(7) Induction of a remarkable conformational change in a human telomeric sequence by the binding of naphthyridine dimer: Inhibition of the elongation of a telomeric repeat by telomerase
Kazuhiko Nakatani, Shinya Hagihara, Shinsuke Sando, Shigeru Sakamoto, Kentaro Yamaguchi, Chihaya Maesawa, Isao Saito
J. Am. Chem. Soc., 2003, 125, 662–666. DOI: 10.1021/ja027055g.
(6) Assessment of the sequence dependency for the binding of 2-aminonaphthyridine to the guanine bulge
Kazuhiko Nakatani, Souta Horie, Takashi Murase, Shinya Hagihara, Isao Saito
Bioorg. Med. Chem., 2003, 11, 2347-2353. DOI: 10.1016/S0968-0896(03)00026-9.
(5) The binding of naphthyridine tetramer to guanine-rich sequences
Yuki Goto, Shinya Hagihara, Akio Kobori, Kazuhiko Nakatani, Isao Saito
Nucleic Acids Res. Suppl., 2003, 3, 133.
(4) 2,6-Diaminonaphthyridine derivatives bind to a single nucleotide bulge in DNA
Hitoshi Suda, Shinya Hagihara, Akio Kobori, Kazuhiko Nakatani, Isao Saito
Nucleic Acids Research Suppl, 2003, 3, 139.
(3) Recognition of DNA mismatch structures
Shinya Hagihira, Kazuhiko Nakatani, Isao Saito
Nucleic Acids Res. Suppl., 2002, 2, 127–128.
(2) Selective intercalation of charge neutral intercalators into GG and CG steps: Implication of HOMO-LUMO interaction for sequence-selective drug intercalation into DNA
Kazuhiko Nakatani, Takahiro Matsuno, Kaoru Adachi, Shinya Hagihara, Isao Saito
J. Am. Chem. Soc., 2001, 123, 5695–5702. DOI: 10.1021/ja003956i.
(1) Site selective formation of thymine glycol-containing oligodeoxynucleotides by oxidation with osmium tetroxide and bipyridine-tethered oligonucleotide
Kazuhiko Nakatani, Shinya Hagihara, Shinsuke Sando, Hiroshi Miyazaki, Kazuhito Tanabe, Isao Saito
J. Am. Chem. Soc., 2000, 122, 6309–6310. DOI: 10.1021/ja0004478.
総説・解説
『化学と工業』3月号「支部発話題欄」特集記事, 2016
日本化学会生体機能関連化学部会ニュースレター No.3, 2015
Shinya Hagihara, Kiichiro Totani, Yukishige Ito.
Chem. Rec., 2006, 6, 290-302.
Yukishige Ito, Shinya Hagihara, Ichiro Matsuo, Kiichiro Totani.
Curr. Opin. Struct. Biol., 2005, 15, 481-489.
戸谷 希一郎, 萩原 伸也, 伊藤 幸成,
有機合成化学協会誌, 2006, 64, 492-501.
有機合成化学協会誌, 2006, 64, 573.
著書