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Publications -Shinya Hagihara-

 

(43) The dynamics of strigolactone perception in Striga hermonthica : a working hypothesis

Yuichiro Tsuchiya,* Masahiko Yoshimura, Shinya Hagihara

J. Exp. Botany 2018, Just Accepted. DOI: 10.1093/jxb/ery061

 

(42) Discovery of shoot branching regulator targeting strigolactone re-ceptor DWARF14

Masahiko Yoshimura, Ayato Sato, Keiko Kuwata, Yoshiaki Inukai, Toshinori Kinoshita, Kenichiro Itami, Yuichiro Tsuchiya, and Shinya Hagihara

ACS Central Science, 2018, 4, 230-234DOI: 10.1021/acscentsci.7b00554

 

(41) Chemical hijacking of auxin signaling with an engineered auxin-TIR1 pair

Naoyuki Uchida, Koji Takahashi, Rie Iwasaki, Ryotaro Yamada, Masahiko Yoshimura, Takaho A. Endo, Seisuke Kimura, Hua Zhang, Mika Nomoto, Yasuomi Tada, Toshinori Kinoshita, Kenichiro Itami, Shinya Hagihara*, and Keiko U. Torii*

Nat. Chem. Biol., 2018, 14, 299-307DOI: 10.1038/nCHeMBIO.2555

 

(40) Discovery of Synthetic Small Molecules that Enhance the Number of Stomata: C-H Functionalization Chemistry for Plant Biology

Asraa Ziadi, Nayuki Uchida, Hiroe Kato, Rina Hisamatsu, Ayato Sato, Shinya Hagihara, Kenichiro Itami and Keiko U. Torii

Chem. Commun., 2017, 53, 9632-9635.

 

(39) Key Structural Elements of Unsymmetrical Cyanine Dyes for Highly Sensitive Fluorescence Turn-On DNA Probes

Kakishi Uno, Taeko Sasaki, Nagisa Sugimoto, Hideto Ito, Taishi Nishihara, Shinya Hagihara, Tetsuya Higashiyama, Narie Sasaki, Yoshikatsu Sato, Kenichito Itami

Chem. Asian. J. 2017, 12, 233-238.

 

(38) High-throughput Assay for Quantification of Aminoglycoside–Ribosome Interaction

Shun Yamashita, Dominik Bergmann, Ayato Sato, Mika Nomoto, Yasuomi Tada, Hans-Ulrich Humpf, Kenichiro Itami and Shinya Hagihara

Chem. Lett. 2016, 45, 1048-1050. DOI:10.1246/cl.160508

 

(37) Making Dimethylamino a Transformable Directing Group by Nickel‐Catalyzed C-N Borylation

Hua Zhang, Shinya Hagihara, and Kenichiro Itami

Chem. Eur. J. 2015 21, 16796-16800. DOI: 10.1002/chem.201503596

 

(36) Probing strigolactone receptors in Striga hermonthica with fluorescence

Yuichiro Tsuchiya, Masahiko Yoshimura, Yoshikatsu Sato, Keiko Kuwata, Shigeo Toh, Duncan Holbrook-Smith, Hua Zhang, Peter McCourt, Kenichiro Itami, Toshinori Kinoshita, Shinya Hagihara

Science 2015, 349, 864-868. DOI: 10.1126/science.aab3831.

 

(35) Aromatic C-H Borylation by Nickel Catalysis

Hua Zhang, Shinya Hagihara, Kenichiro Itami

Chem. Lett. 2015, 44 (6), 779-781. DOI: 10.1246/cl.150154.

 

(34) Development of the crosslinking reactions to RNA triggered by oxidation

Kusano, S.; Haruyama, T.; Ishiyama, S.; Hagihara, S.; Nagatsugi, F.,

Chem. Commun. 2014, 50 (30), 3951-3954. DOI: 10.1039/c3cc49463b.

 

(33) The Crosslink Formation of 2′-OMe Oligonucleotide Containing 2-Amino-6-vinylpurine Protects mRNA from miRNA-Mediated Silencing

Shinya Hagihara, Wei-Chen Lin, Shuhei Kusano, Xiao-guang Chao, Tsuneaki Hori, Shuhei Imoto, and Fumi Nagatsugi

Chembiochem 2013, 14 (12), 1427-1429. DOI: 10.1002/cbic.201300382.

(32) Synthesis of peptide-conjugated light-driven molecular motors and evaluation of their DNA-binding properties

Fumi Nagatsugi, Yousuke Takahashi, Maiko Kobayashi, Shunsuke Kuwahara, Suhei Kusano, Tomoko Chikuni, Shinya Hagihara, Nobuyuki Harada.

Molecular Biosystems 2013, 9 (5), 969-973. DOI: 10.1039/c2mb25520k.

 

(31) Synthesis of 6-amino-2-vinylpurine derivatives for cross-linking and evaluation of the reactivity

Suhei Kusano, Tomoya Sakuraba, Shinya Hagihara, Fumi Nagatsugi

Bioorg. Med. Chem. Lett., 2012, 22, 6957-6961. DOI: 10.1016/j.bmcl.2012.08.122.

 

(30) Production of truncated protein by the crosslink formation of mRNA with 2′-OMe oligoribonucleotide containing 2-amino-6-vinylpurine

Shinya Hagihara, Tsuneaki Hori, Suhei Kusano, Shuhei Imoto, WeiChen Lin, XiaoGuang Chao, Fumi Nagatsugi

Bioorg. Med. Chem. Lett., 2012, 22, 3870-3872.

 

(29) Dependency of the cross-linking reactivity with 2-amino-6-vinylpurine on the neighboring bases

Fumi Nagatsugi, Shinya Hagihara, Shuhei Kusano, Xiau-guang Chao

Nucleic Acid Therapeutics, 2012, 21, 37.

 

(28) Alteration of cross-linking selectivity with the 2′-OMe analogue of 2-amino-6-vinylpurine and evaluation of antisense effects

Shuhei Imoto, Tsuneaki Hori, Shinya Hagihara, Yousuke Taniguchi, Shigeki Sasaki, Fumi Nagatsugi

Bioorg. Med. Chem. Lett., 2010, 20, 6121-6124.

 

(27) Hydrazinoanthrylboronic acids as supramolecular exciton-coupled circular dichroism (ECCD) probes for multivalent catechols, particularly epigallocatechin gallate

Andreas Henning, Shinya Hagihara, Stefan Matile

Chirality, 2009, 21, 826-835.

 

(26) Systematic synthesis and inhibitory activity of haloacetamidyl oligosaccharide derivatives toward cytoplasmic peptide:N-glycanase

Ayako Miyazaki, Ichiro Matsuo, Shinya Hagihara, Ayako Kakegawa, Tadashi Suzuki, Yukishige Ito.

Glycoconj. J., 2009, 26, 133-140.

 

(25) Screening of -basic naphthalene and anthracene amplifiers for -acidic synthetic pore sensors

Shinya Hagihara, Ludovic Gremaud, Guillaume Bollot, Jiri Mareda, Stefan Matile

J. Am. Chem. Soc., 2008, 130, 4347-4351.

 

(24) Signal amplification by conjugate addition for differential sensing with synthetic pores

Shinya Hagihara, Hiroyuki Tanaka, Stefan Matile

Org. Biomol. Chem., 2008, 6, 2259-2262.

 

(23) Boronic acid converters for reactive hydrazide amplifiers: polyphenol sensing in green tea with synthetic pores

Shinya Hagihara, Hiroyuki Tanaka, Stefan Matile

J Am. Chem. Soc., 2008, 130, 5656-5657.

 

(22) Artificial tongues and leaves

Shinya Hagihara, Stefan Matile, Naomi Sakai, et. al.

Pure Appl. Chem., 2008, 80, 1873-1882.

 

(21) Small-molecule binding to the nonquadruplex form of the human telomeric sequence

Yuki Goto, Shinya Hagihara, Masaki Hagihara, Kazuhiko Nakatani

ChemBioChem, 2007, 8, 723-726.

 

(20) Analysis of ER-associated glycoprotein degradation using synthetic glycopeptide probes

Shinya Hagihara, Kazuhito Goda, Ichiro Matsuo, Yukishige Ito

Biochem. Biophys. Res. Commun., 2007, 360, 357–362.

 

(19) Fluorescently labeled inhibitor for profiling cytoplasmic peptide:N-glycanase”

Shinya Hagihara, Ayako Miyazaki, Ichiro Matsuo, Atsushi Tatami, Tadashi Suzuki, Yukishige Ito

Glycobiology, 2007, 17, 1070-1076.

 

(18) Evaluation of mismatch-binding ligands as inhibitors for Rev–RRE interaction

Kazuhiko Nakatani, Souta Horie, Yuki Goto, Akio Kobori, Shinya Hagihara

Bioorg. Med. Chem., 2006, 14, 5384-5388. DOI: 10.1016/j.bmc.2006.03.038.

 

(17) Small-molecule ligand induces nucleotide flipping in (CAG)n trinucleotide repeats

Kazuhiko Nakatani, Shinya Hagihara, Yuki Goto, Akio Kobori, Masaki Hagihara, Gosuke Hayashi, Motoki Kyo, Makoto Nomura, Masaki Mishima, Chojiro Kojima

Nature Chemical Biology, 2005, 1, 39-43. DOI: 10.1038/nchembio708.

 

(16) Thermodynamic analysis of interactions between N-linked sugar chains and F-box protein Fbs1

Shinya Hagihara, Kiichiro Totani, Ichiro Matsuo, Yukishige Ito

J. Med. Chem., 2005, 48, 3126-3129.

 

(15) Design and synthesis of oligosaccharides that interfere with glycoprotein quality-control systems

Midori A. Arai, Ichiro Matsuo, Shinya Hagihara, Kiichiro Totani, Jun-ichi Maruyama, Katsuhiko Kitamoto, Yukishige Ito

ChemBioChem, 2005, 6, 2281-2289.

 

(14) NMR structural analysis of the GG mismatch DNA complexed with naphthyridine dimer

Makoto Nomura, Shinya Hagihara, Yuki Goto, Kazuhiko Nakatani, Chojiro Kojima

Nucleic Acids Symp. Ser., 2005, 49, 213-214.

 

(13) Solution structure of a small-molecular ligand complexed with CAG trinucleotide repeat DNA

Kazuhiko Nakatani, Shinya Hagihara, Yuki Goto, Akio Kobori, Masaki Hagihara, Gosuke Hayashi, Masaki Kyo, Makoto Nomura, Masaki Mishima, Chojiro Kojima

Nucleic Acids Symp. Ser., 2005, 49, 49-50.

 

(12) Synthesis of fluorine substituted oligosaccharide analogues of monoglucosylated glycan chain, a proposed ligand of lectin-chaperone calreticulin and calnexin

Yukishige Ito, Shinya Hagihara, Midori A. Arai, Ichiro Matsuo, Maki Takatani

Glycoconj. J., 2004, 21, 257-266.

 

(11) Synthesis of glycoprotein molecular probes for the analyses of protein quality control system

Kiichiro Totani, Ichiro Matsuo, Maki Takatani, Midori A. Arai, Shinya Hagihara, Yukishige Ito

Glycoconj. J., 2004, 21, 69-74. DOI: 10.1023/B:GLYC.0000043751.18027.c1.

 

(10) Detection of guanine–adenine mismatches by surface plasmon resonance sensor carrying naphthyridine–azaquinolone hybrid on the surface

Shinya Hagihara, Hiroyuki Kumasawa, Yuki Goto, Gosuke Hayashi, Akio Kobori, Isao Saito, Kazuhiko Nakatani

Nucleic Acids Res., 2004, 32, 278-286.

 

(9) Synthesis of asparagine-linked glycan chains: Toward understanding glycoprotein quality control

Ichiro Matsuo, Shinya Hagihara, Kiichiro Totani, Toshinori Kashiwagi, Yukishige Ito

Glycobiology, 2004, 14, 1081-1082.

 

(8) Thermodynamic analysis for the sugar recognition of Fbs1

Shinya Hagihara, Kiichiro Totani, Ichiro Matsuo, Yukishige Ito

Glycobiology, 2004, 14, 1096-1096.

 

(7) Induction of a remarkable conformational change in a human telomeric sequence by the binding of naphthyridine dimer: Inhibition of the elongation of a telomeric repeat by telomerase

Kazuhiko Nakatani, Shinya Hagihara, Shinsuke Sando, Shigeru Sakamoto, Kentaro Yamaguchi, Chihaya Maesawa, Isao Saito

J. Am. Chem. Soc., 2003, 125, 662–666. DOI: 10.1021/ja027055g.

 

(6) Assessment of the sequence dependency for the binding of 2-aminonaphthyridine to the guanine bulge

Kazuhiko Nakatani, Souta Horie, Takashi Murase, Shinya Hagihara, Isao Saito

Bioorg. Med. Chem., 2003, 11, 2347-2353. DOI: 10.1016/S0968-0896(03)00026-9.

 

(5) The binding of naphthyridine tetramer to guanine-rich sequences

Yuki Goto, Shinya Hagihara, Akio Kobori, Kazuhiko Nakatani, Isao Saito

Nucleic Acids Res. Suppl., 2003, 3, 133.

 

(4) 2,6-Diaminonaphthyridine derivatives bind to a single nucleotide bulge in DNA

Hitoshi Suda, Shinya Hagihara, Akio Kobori, Kazuhiko Nakatani, Isao Saito

Nucleic Acids Research Suppl, 2003, 3, 139.

 

(3) Recognition of DNA mismatch structures

Shinya Hagihira, Kazuhiko Nakatani, Isao Saito

Nucleic Acids Res. Suppl., 2002, 2, 127–128.

 

(2) Selective intercalation of charge neutral intercalators into GG and CG steps: Implication of HOMO-LUMO interaction for sequence-selective drug intercalation into DNA

Kazuhiko Nakatani, Takahiro Matsuno, Kaoru Adachi, Shinya Hagihara, Isao Saito

J. Am. Chem. Soc., 2001, 123, 5695–5702. DOI: 10.1021/ja003956i.

 

(1) Site selective formation of thymine glycol-containing oligodeoxynucleotides by oxidation with osmium tetroxide and bipyridine-tethered oligonucleotide

Kazuhiko Nakatani, Shinya Hagihara, Shinsuke Sando, Hiroshi Miyazaki, Kazuhito Tanabe, Isao Saito

J. Am. Chem. Soc., 2000, 122, 6309–6310. DOI: 10.1021/ja0004478.

 

総説・解説

  1. 植物ホルモン受容体のケミカルバイオロジー

『化学と工業』3月号「支部発話題欄」特集記事, 2016

 

  1. ストライガ発芽機構の解明にむけた化学的アプローチ

日本化学会生体機能関連化学部会ニュースレター No.3, 2015

 

  1. Exploration of oligosaccharide-protein interactions in glycoprotein quality control by synthetic approaches

Shinya Hagihara, Kiichiro Totani, Yukishige Ito.

Chem. Rec., 2006, 6, 290-302.

 

  1. Structural approaches to the study of oligosaccharides in glycoprotein quality control

Yukishige Ito, Shinya Hagihara, Ichiro Matsuo, Kiichiro Totani.

Curr. Opin. Struct. Biol., 2005, 15, 481-489.

 

  1. 有機合成化学による糖タンパク質糖鎖の機能解明

戸谷 希一郎, 萩原 伸也, 伊藤 幸成,

有機合成化学協会誌, 2006, 64, 492-501.

 

  1. “分子シャペロン”

有機合成化学協会誌, 2006, 64, 573.

 

著書

  1. “タンパク質品質管理の機構解明に向けた糖鎖プローブの合成” 萩原 伸也, 伊藤 幸成. 『ゲノム化学—医学、分子生物学への応用と展開』化学同人、pp195-202, (2007)

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