Blog

Dehydrogenative Synthesis of 2,2′-Bipyridyls through Regioselective Pyridine Dimerization

“Dehydrogenative Synthesis of 2,2′-Bipyridyls through Regioselective Pyridine Dimerization”
Shuya Yamada, Takeshi Kaneda, Philip Steib, Kei Murakami,* Kenichiro Itami*
Angew. Chem., Int. Ed. 2019, 58, 8341–8345.DOI:10.1002/anie.201814701.

The palladium-catalyzed dehydrogenative dimerization of pyridines is described. The dimerization reaction takes place smoothly to provide the corresponding 2,2′-bipyridyls with excellent C2-selectivity. The present protocol allows a concise synthesis of twisted 3,3′-disubstituted-2,2′-bipyridyls that is hitherto difficult to access with conventional methods.

Related post

  1. A Nickel Catalyst for the Additi…
  2. Nickel-Catalyzed C−H/C−O Couplin…
  3. Rapid access to polycyclic thiop…
  4. Synthesis and Properties of Cycl…
  5. Topologically Unique Molecular N…
  6. Oxidative Biaryl Coupling of Thi…
  7. Synthesis and characterization o…
  8. Construction of Covalent Organic…

最近の記事

Flickr@Itamilab

天池先輩からコーヒースープ伴夫妻からのお歳暮です!潤さん、宮村さん、ありがとうございます!!武藤さん、ビールありがとうございます!平賀大都わーいやなさん、あつしさん、ありがとうございます!!だいぶ前だけど、Stripes look #ootdHalloween lookラインを洗う時ですら格好良く。戸谷先生教育実習!imageけいしゅう、誕生日おめでとう!誕生日は英吉家!!3年生に名古屋ぼろ勝ちアピール中!!アリシア卒業おめでとう女子会!
PAGE TOP