Blog

Cu-Catalyzed aromatic C–H imidation with N-fluorobenzenesulfonimide: mechanistic details and predictive models

%e3%82%b9%e3%82%af%e3%83%aa%e3%83%bc%e3%83%b3%e3%82%b7%e3%83%a7%e3%83%83%e3%83%88-2016-11-08-18-09-09

Brandon E. Haines, Takahiro Kawakami, Keiko Kuwata, Kei Murakami, Kenichiro Itami and Djamaladdin G. Musaev

Chem. Sci. 2016, Advance article. DOI: 10.1039/C6SC04145K

The CuBr-catalyzed C–H imidation of arenes, previously reported by us, utilizes an inexpensive catalyst and is applicable to a broad scope of complex arenes. The computational and experimental study reported here shows that the mechanism of the reaction is comprised of two parts: (1) generation of the active dinuclear CuII–CuII catalyst; and (2) the catalytic cycle for the C–H bond imidation of arenes. A simple predictive tool was developed and experimentally validated to determine the regiochemical outcome for a given substrate.

Highlighted in C&EN news.

Related post

  1. Dragmacidin D Synthesis of Dragmacidin D via D…
  2. Synthesis of a carbon nanobelt
  3. tert-Butoxide-Mediated C-H Bond …
  4. Synthesis and Properties of Cycl…
  5. Creation of negatively curved po…
  6. β-Selective C–H Arylation of Pyr…
  7. Size-Selective Complexation and …
  8. Topological molecular nanocarbon…

Twitter@Itami Lab

Itami Lab Facebook

Instagram@Itami Lab

最近の記事

Flickr@Itamilab

天池先輩からコーヒースープ伴夫妻からのお歳暮です!潤さん、宮村さん、ありがとうございます!!武藤さん、ビールありがとうございます!平賀大都わーいやなさん、あつしさん、ありがとうございます!!だいぶ前だけど、Stripes look #ootdHalloween lookラインを洗う時ですら格好良く。戸谷先生教育実習!imageけいしゅう、誕生日おめでとう!誕生日は英吉家!!3年生に名古屋ぼろ勝ちアピール中!!アリシア卒業おめでとう女子会!
PAGE TOP