Blog

Nickel-Catalyzed C-H Arylation of Azoles with Haloarenes: Scope, Mechanism, and Applications to the Synthesis of Bioactive Molecules

Takuya Yamamoto, Kei Muto, Masato Komiyama, Jerôme Canivet, Junichiro Yamaguchi, and Kenichiro Itami*

Chem. Eur. J2011, Early View

DOI: 10.1002/chem.201101091

New couples:

Novel Ni-based catalytic systems for the -H arylation of azoles with haloarenes have been developed (see scheme). Mechanistic studies as well as applications to the synthesis of biologically active com- pounds (febuxostat, tafamidis, and texaline) are also described.

Related post

  1. Fe-Catalyzed Oxidative Coupling …
  2. Carbon Nanosheets by Morphology-…
  3. Size-selective synthesis of [9]-…
  4. Synthesis of Cycloiptycenes from…
  5. Reversible modulation of circadi…
  6. Iridium Catalysis for C-H Bond A…
  7. Rapid Access to Nanographenes an…
  8. Lithium-mediated mechanochemical…

Twitter@Itami Lab

Itami Lab Facebook

Instagram@Itami Lab

最近の記事

Flickr@Itamilab

天池先輩からコーヒースープ伴夫妻からのお歳暮です!潤さん、宮村さん、ありがとうございます!!武藤さん、ビールありがとうございます!平賀大都わーいやなさん、あつしさん、ありがとうございます!!だいぶ前だけど、Stripes look #ootdHalloween lookラインを洗う時ですら格好良く。戸谷先生教育実習!imageけいしゅう、誕生日おめでとう!誕生日は英吉家!!3年生に名古屋ぼろ勝ちアピール中!!アリシア卒業おめでとう女子会!
PAGE TOP