Blog

Decarbonylative C–H Coupling of Azoles and Aryl Esters: Unprecedented Nickel Catalysis and Application to the Synthesis of Muscoride A

 

Kazuma Amaike, Kei Muto, Junichiro Yamaguchi, and Kenichiro Itami

J. Am. Chem. Soc. 2012, ASAP. DOI: 10.1021/ja306062c

 

A nickel-catalyzed decarbonylative C−H biaryl coupling of azoles and aryl esters is described. The newly developed catalytic system does not require the use of expensive metal catalysts or silver- or copper-based stoichiometric oxidants. We have successfully applied this new C−H arylation reaction to a convergent formal synthesis of muscoride A.

 

Related post

  1. Cycloparaphenylene-Based Ionic D…
  2. Laterally π-Extended Dithia[6]he…
  3. A Water-soluble Warped Nanograph…
  4. Hindered Biaryls by C–H Coupling…
  5. Synthesis of Heptagon-Containing…
  6. Ultra-narrow-band near-infrared …
  7. Synthesis and Properties of [8]-…
  8. Synthesis of Bioactive Compounds…

最近の記事

Flickr@Itamilab

天池先輩からコーヒースープ伴夫妻からのお歳暮です!潤さん、宮村さん、ありがとうございます!!武藤さん、ビールありがとうございます!平賀大都わーいやなさん、あつしさん、ありがとうございます!!だいぶ前だけど、Stripes look #ootdHalloween lookラインを洗う時ですら格好良く。戸谷先生教育実習!imageけいしゅう、誕生日おめでとう!誕生日は英吉家!!3年生に名古屋ぼろ勝ちアピール中!!アリシア卒業おめでとう女子会!
PAGE TOP