Hua Zhang


Hua Zhang



2013-present: JSPS Postdoctoral Fellow, Organic Chemistry, Department of Chemistry, Graduate School of Science, Nagoya University

(Prof. Kenichiro Itami, Assoc Prof. Shinya Hagihara)

2008-2013: Ph.D., Organic Chemistry, College of Chemistry & Molecular Sciences, Wuhan University (Prof. Aiwen Lei)

2004-2008: B.S., Organic Chemistry, College of Chemistry & Molecular Sciences, Wuhan University (Prof. Aiwen Lei)


Organic Chemistry, Chemistry Biology


Communication Articles

(1) K. Ozaki, H. Zhang, H. Ito, A. Lei, K. Itami, One-shot indole-to-carbazole π-extension by a Pd­–Cu­–Ag trimetallic system, Chem. Sci. 2013, 4, 3416.

(2) R. Shi, L. Lu, H. Zhang, B. Chen, Y. Sha, C. Liu, A. Lei, Palladium/Copper-catalyzed oxidative C­–H alkenylation/N-dealkylative carbonylation of tertiary anilines, Angew. Chem. Int. Ed. 2013, 52, 10582.

(3) H. Zhang, R. Shi, A. Ding, L. Lu, B. Chen, A. Lei, Transition-metal-free alkoxycarbonylation of aryl halides, Angew. Chem. Int. Ed. 2012, 51, 12542-12545.

(4) H. Zhang, R. Shi, P. Gan, C. Liu, A. Ding, Q. Wang, A. Lei, Palladium-Catalyzed Oxidative Double C–H Functionalization/Carbonylation towards Xanthone Syntheses, Angew. Chem. Int. Ed. 2012, 51, 5204(Hot Paper)

(5) H. Zhang, D. Liu, C. Chen, C. Liu, A. Lei, Palladium-Catalyzed Regioselective Aerobic Oxidative C–H/N–H Carbonylation of Heteroarenes under Base-Free Conditions, Chem. Eur. J. 2011, 17, 9581.

(6) W. Liu, H. Cao, H. Zhang, H. Zhang, K. Chung, C. He, H. Wang, F. Kwong, A. Lei, Organocatalysis in Cross-Coupling: DMEDA-Catalyzed Direct C–H Arylation of Unactivated Benzene, J. Am. Chem. Soc. 2010, 132, 16737.

(7) L. Jin, H. Zhang, P. Li, J. Sowa, A. Lei, What is the Rate of the Csp(2)-Csp(2) Reductive Elimination Step? Revealing an Unusually Fast Ni-Catalyzed Negishi-Type Oxidative Coupling Reaction, J. Am. Chem. Soc. 2009, 131, 9892.

(8) J. Liu, H. Wang, H. Zhang, X. Wu, H. Zhang, Y. Deng, Z. Yang, A. Lei, Identification of a Highly Efficient Alkylated Pincer Thioimido-Palladium(II) Complex as the Active Catalyst in Negishi Coupling, Chem. Eur. J. 2009, 15, 4437.

(9) J. Liu, Y. Deng, H. Wang, H. Zhang, G. Yu, B. Wu, H. Zhang, Q. Li, T. Marder, Z. Yang, A. Lei, Effective Pd-nanoparticle (PdNP)-catalyzed Negishi coupling involving alkylzinc reagents at room temperature, Org. Lett. 2008, 10, 2661.

(10) M. Chen, Y. Weng, M. Guo, H. Zhang, A. Lei, Nickel-catalyzed reductive cyclization of unactivated 1,6-enynes in the presence of organozinc reagents, Angew. Chem. Int. Ed. 2008, 47, 2279.

Review & Book

(1) H. Zhang, C. Liu, A. Lei, CHAPTER 9 C­–H Bond Formation by C­–H Carboxylation or Carbonylation, Science of Synthesis Reference Library: Catalytic Transformations via C-H Activation (C-C, C-N, C-O, C-Hal and C-B Bond Formation), 2013, invited.

(2) A. Lei, H. Zhang, CHAPTER 9 Transition Metal-Catalysed Direct Arylation of Unactivated Arenes with Aryl Halides, C­–H and C­–X Bond Functionalization: Transition Metal Mediation, 2013, 310-327.

(3) C. Liu, H. Zhang, W. Shi, A. Lei, Bond Formations between Two Nucleophiles: Transition Metal Catalyzed Oxidative Cross-Coupling Reactions, Chem. Rev. 2011, 111, 1780.

(4) Q. Liu, H. Zhang, A. Lei, Oxidative Carbonylation Reactions: Organometallic Compounds (R–M) or Hydrocarbons (R–H) as Nucleophiles Angew. Chem. Int. Ed. 2011, 50, 10788.



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